CN107921048A - 自分泌运动因子抑制剂及其用途 - Google Patents
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Abstract
Description
化合物 | IC50(μM) |
化合物A | A |
化合物B | A |
化合物C | A |
化合物D | A |
化合物E | A |
化合物F | A |
化合物G | A |
化合物H | A |
化合物I | A |
Claims (53)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202211516732.7A CN116059203A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
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US201562167216P | 2015-05-27 | 2015-05-27 | |
US62/167,216 | 2015-05-27 | ||
PCT/US2016/033933 WO2016191427A1 (en) | 2015-05-27 | 2016-05-24 | Autotaxin inhibitors and uses thereof |
Related Child Applications (1)
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CN202211516732.7A Division CN116059203A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
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CN107921048A true CN107921048A (zh) | 2018-04-17 |
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CN202211516732.7A Pending CN116059203A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
CN201680044106.9A Pending CN107921048A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
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CN202211516732.7A Pending CN116059203A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
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US (2) | US10632104B2 (zh) |
EP (2) | EP4026549A1 (zh) |
JP (2) | JP6873919B2 (zh) |
KR (2) | KR20240060887A (zh) |
CN (2) | CN116059203A (zh) |
AU (3) | AU2016268250B2 (zh) |
BR (1) | BR122023011445B1 (zh) |
CA (1) | CA2986759A1 (zh) |
EA (2) | EA039684B1 (zh) |
ES (1) | ES2915267T3 (zh) |
HK (1) | HK1253587A1 (zh) |
IL (2) | IL280863B2 (zh) |
MX (2) | MX2017015225A (zh) |
SG (1) | SG10201911204WA (zh) |
WO (1) | WO2016191427A1 (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112190708A (zh) * | 2019-07-08 | 2021-01-08 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
CN113056266A (zh) * | 2018-09-18 | 2021-06-29 | 梅塔科林公司 | 用于治疗疾病的法尼醇x受体激动剂 |
CN114767863A (zh) * | 2022-04-29 | 2022-07-22 | 西北工业大学 | 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用 |
CN116239577A (zh) * | 2023-03-27 | 2023-06-09 | 沈阳药科大学 | 一种制备Cudetaxestat的方法 |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2930737C (en) | 2013-11-22 | 2023-02-21 | Pharmakea, Inc. | Autotaxin inhibitor compounds |
KR20240060887A (ko) | 2015-05-27 | 2024-05-08 | 사브레 테라퓨틱스 엘엘씨 | 오토탁신 억제제 및 이의 용도 |
CN107021915A (zh) * | 2017-04-27 | 2017-08-08 | 李亚庆 | 一种治疗妇科炎症的化合物及制备方法和应用 |
CA3072346A1 (en) * | 2017-08-14 | 2019-02-21 | Camp4 Therapeutics Corporation | Methods of treating liver diseases |
WO2019172651A1 (ko) | 2018-03-06 | 2019-09-12 | 주식회사 엘지화학 | 편광판 및 이를 포함하는 화상 표시 장치 |
WO2023215196A1 (en) * | 2022-05-03 | 2023-11-09 | Sabre Therapeutics Llc | Polymorphic and salt forms of the autotaxin inhibitor cudetaxestat |
WO2023215684A1 (en) * | 2022-05-05 | 2023-11-09 | The Trustees Of Indiana University | Therapeutic strategies to manage facial contractures post injury |
GR1010570B (el) | 2022-12-22 | 2023-11-17 | Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., | 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης |
WO2024180520A1 (en) * | 2023-03-02 | 2024-09-06 | Zydus Lifesciences Limited | Novel atx inhibitors |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103201262A (zh) * | 2010-08-20 | 2013-07-10 | 艾米拉医药股份有限公司 | 自分泌运动因子抑制剂及其用途 |
WO2015048301A1 (en) * | 2013-09-26 | 2015-04-02 | Pharmakea, Inc. | Autotaxin inhibitor compounds |
CN105793253A (zh) * | 2013-11-22 | 2016-07-20 | 法玛克亚公司 | 自分泌运动因子抑制剂化合物 |
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