CN116059203A - 自分泌运动因子抑制剂及其用途 - Google Patents
自分泌运动因子抑制剂及其用途 Download PDFInfo
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- CN116059203A CN116059203A CN202211516732.7A CN202211516732A CN116059203A CN 116059203 A CN116059203 A CN 116059203A CN 202211516732 A CN202211516732 A CN 202211516732A CN 116059203 A CN116059203 A CN 116059203A
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- cancer
- disease
- autotaxin inhibitor
- compound
- autotaxin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
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- Psychiatry (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562167216P | 2015-05-27 | 2015-05-27 | |
| US62/167,216 | 2015-05-27 | ||
| CN201680044106.9A CN107921048A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
| PCT/US2016/033933 WO2016191427A1 (en) | 2015-05-27 | 2016-05-24 | Autotaxin inhibitors and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680044106.9A Division CN107921048A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116059203A true CN116059203A (zh) | 2023-05-05 |
Family
ID=57393709
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211516732.7A Pending CN116059203A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
| CN201680044106.9A Pending CN107921048A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680044106.9A Pending CN107921048A (zh) | 2015-05-27 | 2016-05-24 | 自分泌运动因子抑制剂及其用途 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10632104B2 (enExample) |
| EP (2) | EP4026549A1 (enExample) |
| JP (2) | JP6873919B2 (enExample) |
| KR (2) | KR102663569B1 (enExample) |
| CN (2) | CN116059203A (enExample) |
| AU (4) | AU2016268250B2 (enExample) |
| BR (1) | BR122023011445B1 (enExample) |
| CA (1) | CA2986759C (enExample) |
| EA (2) | EA036337B1 (enExample) |
| ES (1) | ES2915267T3 (enExample) |
| IL (2) | IL280863B2 (enExample) |
| MX (2) | MX2017015225A (enExample) |
| SG (1) | SG10201911204WA (enExample) |
| WO (1) | WO2016191427A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20210957T1 (hr) | 2013-11-22 | 2021-09-17 | Sabre Therapeutics Llc | Spojevi inhibitori autotaksina |
| EP4026549A1 (en) | 2015-05-27 | 2022-07-13 | Sabre Therapeutics LLC | Autotaxin inhibitors and uses thereof |
| CN107021915A (zh) * | 2017-04-27 | 2017-08-08 | 李亚庆 | 一种治疗妇科炎症的化合物及制备方法和应用 |
| EP3668993A4 (en) * | 2017-08-14 | 2021-05-12 | Camp4 Therapeutics Corporation | HEPATIC DISEASE TREATMENT METHODS |
| WO2019172651A1 (ko) | 2018-03-06 | 2019-09-12 | 주식회사 엘지화학 | 편광판 및 이를 포함하는 화상 표시 장치 |
| CA3112414A1 (en) * | 2018-09-18 | 2020-03-26 | Metacrine, Inc. | Farnesoid x receptor agonists for the treatment of disease |
| CN112190708B (zh) * | 2019-07-08 | 2023-09-05 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
| AU2022421244A1 (en) | 2021-12-22 | 2024-07-11 | Camp4 Therapeutics Corporation | Modulation of gene transcription using antisense oligonucleotides targeting regulatory rnas |
| CN114767863B (zh) * | 2022-04-29 | 2024-01-30 | 西北工业大学 | 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用 |
| WO2023215196A1 (en) * | 2022-05-03 | 2023-11-09 | Sabre Therapeutics Llc | Polymorphic and salt forms of the autotaxin inhibitor cudetaxestat |
| US20250281486A1 (en) * | 2022-05-05 | 2025-09-11 | The Trustees Of Indiana University | Therapeutic strategies to manage facial contractures post injury |
| GR1010570B (el) | 2022-12-22 | 2023-11-17 | Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., | 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης |
| TW202502735A (zh) * | 2023-03-02 | 2025-01-16 | 印度商吉德斯生命科學有限公司 | 新穎atx抑制劑 |
| CN116239577A (zh) * | 2023-03-27 | 2023-06-09 | 沈阳药科大学 | 一种制备Cudetaxestat的方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103201262A (zh) * | 2010-08-20 | 2013-07-10 | 艾米拉医药股份有限公司 | 自分泌运动因子抑制剂及其用途 |
| WO2015048301A1 (en) * | 2013-09-26 | 2015-04-02 | Pharmakea, Inc. | Autotaxin inhibitor compounds |
| WO2015077503A1 (en) * | 2013-11-22 | 2015-05-28 | Pharmakea, Inc. | Autotaxin inhibitor compounds |
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| US5210574A (en) | 1991-03-08 | 1993-05-11 | Mita Industrial Co., Ltd. | Photosensitive drum body-mounting mechanism including a drive coupling member with a coupling protrusion adapted to bite into the inner surface of the mechanism's photosensitive drum |
| US5186522A (en) | 1991-09-24 | 1993-02-16 | Midland Brake, Inc. | Air dryer purge line |
| EP0630453B1 (en) | 1992-11-10 | 1998-01-28 | Fluid Power Industries, Incorporated | Solenoid valve assembly |
| US5407368A (en) | 1992-12-15 | 1995-04-18 | Minnesota Mining And Manufacturing Company | Electrode connector |
| US5761473A (en) | 1993-01-08 | 1998-06-02 | International Business Machines Corporation | Method and system for increased instruction synchronization efficiency in a superscalar processsor system utilizing partial data dependency interlocking |
| US5564949A (en) | 1995-01-05 | 1996-10-15 | Thomas & Betts Corporation | Shielded compact data connector |
| JP2664048B2 (ja) | 1995-03-27 | 1997-10-15 | 科学技術庁金属材料技術研究所長 | 六フッ化二ケイ素の合成法 |
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