CN107921048A - 自分泌运动因子抑制剂及其用途 - Google Patents

自分泌运动因子抑制剂及其用途 Download PDF

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Publication number
CN107921048A
CN107921048A CN201680044106.9A CN201680044106A CN107921048A CN 107921048 A CN107921048 A CN 107921048A CN 201680044106 A CN201680044106 A CN 201680044106A CN 107921048 A CN107921048 A CN 107921048A
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China
Prior art keywords
compound
mammal
autotaxin
cancer
disease
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Pending
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CN201680044106.9A
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English (en)
Chinese (zh)
Inventor
格雷琴·贝恩
吉莉安·弗朗西斯·埃文斯
约翰·霍华德·哈钦森
戴维·罗纳根
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Cybertherapy Co ltd
Etkosco Corp
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Pharmakea Inc
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Application filed by Pharmakea Inc filed Critical Pharmakea Inc
Priority to CN202211516732.7A priority Critical patent/CN116059203A/zh
Publication of CN107921048A publication Critical patent/CN107921048A/zh
Pending legal-status Critical Current

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Neurosurgery (AREA)
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  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
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  • Vascular Medicine (AREA)
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CN201680044106.9A 2015-05-27 2016-05-24 自分泌运动因子抑制剂及其用途 Pending CN107921048A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202211516732.7A CN116059203A (zh) 2015-05-27 2016-05-24 自分泌运动因子抑制剂及其用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562167216P 2015-05-27 2015-05-27
US62/167,216 2015-05-27
PCT/US2016/033933 WO2016191427A1 (en) 2015-05-27 2016-05-24 Autotaxin inhibitors and uses thereof

Related Child Applications (1)

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CN202211516732.7A Division CN116059203A (zh) 2015-05-27 2016-05-24 自分泌运动因子抑制剂及其用途

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CN107921048A true CN107921048A (zh) 2018-04-17

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CN201680044106.9A Pending CN107921048A (zh) 2015-05-27 2016-05-24 自分泌运动因子抑制剂及其用途
CN202211516732.7A Pending CN116059203A (zh) 2015-05-27 2016-05-24 自分泌运动因子抑制剂及其用途

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US (2) US10632104B2 (enExample)
EP (2) EP3302490B1 (enExample)
JP (2) JP6873919B2 (enExample)
KR (2) KR20240060887A (enExample)
CN (2) CN107921048A (enExample)
AU (4) AU2016268250B2 (enExample)
BR (1) BR122023011445B1 (enExample)
CA (1) CA2986759C (enExample)
EA (2) EA039684B1 (enExample)
ES (1) ES2915267T3 (enExample)
IL (2) IL280863B2 (enExample)
MX (2) MX2017015225A (enExample)
SG (1) SG10201911204WA (enExample)
WO (1) WO2016191427A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190708A (zh) * 2019-07-08 2021-01-08 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
CN113056266A (zh) * 2018-09-18 2021-06-29 梅塔科林公司 用于治疗疾病的法尼醇x受体激动剂
CN114767863A (zh) * 2022-04-29 2022-07-22 西北工业大学 一种enpp2基因或蛋白在调控结直肠癌细胞中的应用
CN116239577A (zh) * 2023-03-27 2023-06-09 沈阳药科大学 一种制备Cudetaxestat的方法

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Publication number Priority date Publication date Assignee Title
WO2015077503A1 (en) 2013-11-22 2015-05-28 Pharmakea, Inc. Autotaxin inhibitor compounds
AU2016268250B2 (en) 2015-05-27 2020-08-27 Sabre Therapeutics Llc Autotaxin inhibitors and uses thereof
CN107021915A (zh) * 2017-04-27 2017-08-08 李亚庆 一种治疗妇科炎症的化合物及制备方法和应用
EP3668993A4 (en) * 2017-08-14 2021-05-12 Camp4 Therapeutics Corporation HEPATIC DISEASE TREATMENT METHODS
WO2019172651A1 (ko) 2018-03-06 2019-09-12 주식회사 엘지화학 편광판 및 이를 포함하는 화상 표시 장치
IL313660A (en) 2021-12-22 2024-08-01 Camp4 Therapeutics Corp Modulation of gene transcription using antisense oligonucleotides targeting regulatory RNAs
CA3251769A1 (en) * 2022-05-03 2023-11-09 Sabre Therapeutics Llc POLYMORPHIC AND SALINE FORMS OF THE AUTOTAXIN INHIBITOR CUDETAXESTAT
US20250281486A1 (en) * 2022-05-05 2025-09-11 The Trustees Of Indiana University Therapeutic strategies to manage facial contractures post injury
GR1010570B (el) 2022-12-22 2023-11-17 Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Α.Β.Ε.Ε., 4-(2-(4-((2,4-διοξοθειαζολιδιν-5-υλ)μεθυλ)φαινοξυ) παραγωγα με δραση αναστολης της αυτοταξινης
TW202502735A (zh) * 2023-03-02 2025-01-16 印度商吉德斯生命科學有限公司 新穎atx抑制劑

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103201262A (zh) * 2010-08-20 2013-07-10 艾米拉医药股份有限公司 自分泌运动因子抑制剂及其用途
WO2015048301A1 (en) * 2013-09-26 2015-04-02 Pharmakea, Inc. Autotaxin inhibitor compounds
CN105793253A (zh) * 2013-11-22 2016-07-20 法玛克亚公司 自分泌运动因子抑制剂化合物

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