AU2014364589B2 - Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof - Google Patents

Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof Download PDF

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Publication number
AU2014364589B2
AU2014364589B2 AU2014364589A AU2014364589A AU2014364589B2 AU 2014364589 B2 AU2014364589 B2 AU 2014364589B2 AU 2014364589 A AU2014364589 A AU 2014364589A AU 2014364589 A AU2014364589 A AU 2014364589A AU 2014364589 B2 AU2014364589 B2 AU 2014364589B2
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Australia
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peptide
residues
amino acid
staple
lipids
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AU2014364589A
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AU2014364589A1 (en
Inventor
Peter G. Schultz
Weijun Shen
Pengyu YANG
Huafei ZOU
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Scripps Research Institute
California Institute for Biomedical Research
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Scripps Research Institute
California Institute for Biomedical Research
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
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  • Animal Behavior & Ethology (AREA)
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  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
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  • Obesity (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
AU2014364589A 2013-12-18 2014-12-17 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof Active AU2014364589B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361917816P 2013-12-18 2013-12-18
US61/917,816 2013-12-18
PCT/US2014/070977 WO2015095406A1 (en) 2013-12-18 2014-12-17 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof

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Publication Number Publication Date
AU2014364589A1 AU2014364589A1 (en) 2016-07-07
AU2014364589B2 true AU2014364589B2 (en) 2020-02-27

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US (5) US10039809B2 (enExample)
EP (2) EP4212180A1 (enExample)
JP (1) JP6572497B2 (enExample)
KR (1) KR102455171B1 (enExample)
CN (1) CN106456589B (enExample)
AU (1) AU2014364589B2 (enExample)
CA (1) CA2933701C (enExample)
WO (1) WO2015095406A1 (enExample)

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JP7208020B2 (ja) 2016-06-29 2023-01-18 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン誘導体、その結合体、及びそれを含む組成物、並びにその治療的用途
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CN113024635B (zh) * 2019-12-25 2023-12-19 中国医学科学院药物研究所 一类订书肽化合物及其药物组合物的用途
MX2023006189A (es) * 2020-11-27 2023-07-04 D&D Pharmatech Inc Formulacion oral de conjugado de material biologicamente activo que tiene acoplada un resto de biotina, un resto de acido graso o una combinacion de estos.
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