AU2013286093B2 - Complexes of cytomegalovirus proteins - Google Patents
Complexes of cytomegalovirus proteins Download PDFInfo
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- AU2013286093B2 AU2013286093B2 AU2013286093A AU2013286093A AU2013286093B2 AU 2013286093 B2 AU2013286093 B2 AU 2013286093B2 AU 2013286093 A AU2013286093 A AU 2013286093A AU 2013286093 A AU2013286093 A AU 2013286093A AU 2013286093 B2 AU2013286093 B2 AU 2013286093B2
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- 108700010903 cytomegalovirus proteins Proteins 0.000 title claims 2
- 241000701024 Human betaherpesvirus 5 Species 0.000 claims abstract description 296
- 238000000034 method Methods 0.000 claims abstract description 89
- 239000000203 mixture Substances 0.000 claims abstract description 86
- 230000008569 process Effects 0.000 claims abstract description 53
- 102000003886 Glycoproteins Human genes 0.000 claims abstract description 40
- 108090000288 Glycoproteins Proteins 0.000 claims abstract description 40
- 230000002163 immunogen Effects 0.000 claims abstract description 29
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- 108020004707 nucleic acids Proteins 0.000 claims description 105
- 150000007523 nucleic acids Chemical class 0.000 claims description 105
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- 208000015181 infectious disease Diseases 0.000 claims description 13
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| CN104838000B (zh) | 2012-07-27 | 2022-12-20 | 希望之城 | 一种递送ul128复合体和预防cmv感染的mva疫苗 |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| ES2868427T3 (es) * | 2013-12-03 | 2021-10-21 | Hookipa Biotech Ag | Vacunas contra el CMV |
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| PE20170301A1 (es) * | 2014-05-08 | 2017-03-30 | Pfizer | Medios y metodos para el tratamiento cmv |
| EP3015475A1 (en) | 2014-10-31 | 2016-05-04 | Novartis AG | Mammalian cells expressing cytomegalovirus antigens |
| EP3048114A1 (en) * | 2015-01-22 | 2016-07-27 | Novartis AG | Cytomegalovirus antigens and uses thereof |
| EP3047856A1 (en) * | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv antigens and uses thereof |
| EP3347045A4 (en) | 2015-09-10 | 2019-08-28 | City of Hope | MVA-GH / GL-PC VACCINATED ANTIBODIES FOR NEUTRALIZING THE INFECTIOSITY OF HUMAN CYTOMEGALOVIRUS AND METHOD THEREFOR |
| JP6921833B2 (ja) * | 2015-10-22 | 2021-08-18 | モデルナティーエックス， インコーポレイテッド | ヒトサイトメガロウイルスワクチン |
| CN113181106A (zh) | 2016-01-11 | 2021-07-30 | 沃达瑞公司 | 微针组合物及其使用方法 |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EP3528821A4 (en) | 2016-10-21 | 2020-07-01 | ModernaTX, Inc. | HUMAN CYTOMEGALOVIRUS VACCINE |
| JP2020515522A (ja) * | 2017-01-27 | 2020-05-28 | ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | 免疫応答を誘導するヘルペスウイルスエンベロープタンパク質の組み合わせのワクチン組成物 |
| WO2018187325A1 (en) | 2017-04-04 | 2018-10-11 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| US20230248820A1 (en) | 2017-04-19 | 2023-08-10 | Glaxosmithkline Biologicals, S.A. | Modified cytomegalovirus proteins and stabilized complexes |
| EP3658581A1 (en) * | 2017-07-24 | 2020-06-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies and peptides to treat hcmv related diseases |
| IL272281B2 (en) | 2017-07-28 | 2023-04-01 | Janssen Vaccines Prevention B V | Methods and preparations for heterologous reprna vaccines |
| AU2018331874B2 (en) | 2017-09-13 | 2022-06-02 | Sanofi Pasteur | Human cytomegalovirus immunogenic composition |
| EP3758747A1 (en) * | 2018-02-28 | 2021-01-06 | University of Washington | Self-asssembling nanostructure vaccines |
| IL278418B2 (en) | 2018-05-04 | 2024-01-01 | Spybiotech Ltd | Vaccine composition |
| JP7584405B2 (ja) * | 2018-10-17 | 2024-11-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変されたサイトメガロウイルスタンパク質及び安定化された複合体 |
| AU2019397719B2 (en) | 2018-12-10 | 2023-11-09 | Km Biologics Co., Ltd. | Vaccine for preventing or treating congenital infection with cytomegalovirus |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EP4004018A1 (en) | 2019-07-24 | 2022-06-01 | GlaxoSmithKline Biologicals SA | Modified human cytomegalovirus proteins |
| KR102837045B1 (ko) * | 2020-06-09 | 2025-07-23 | 케이엠 바이올로직스 가부시키가이샤 | 사이토메갈로바이러스의 gB와 펜타머의 융합 단백질 및 당해 융합 단백질을 포함하는 백신 |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| AU2021367917A1 (en) | 2020-10-28 | 2023-06-22 | Sanofi Pasteur | Liposomes containing tlr4 agonist, preparation and uses thereof |
| PE20240083A1 (es) * | 2021-02-24 | 2024-01-16 | Pfizer | Nuevas regiones modulables farmacologicamente en el polipeptido de la glicoproteina b del citomegalovirus humano y metodos de uso de las mismas |
| US20250101067A1 (en) | 2022-01-28 | 2025-03-27 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
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