CA2878344A1 - Complexes of cytomegalovirus proteins - Google Patents
Complexes of cytomegalovirus proteins Download PDFInfo
- Publication number
- CA2878344A1 CA2878344A1 CA2878344A CA2878344A CA2878344A1 CA 2878344 A1 CA2878344 A1 CA 2878344A1 CA 2878344 A CA2878344 A CA 2878344A CA 2878344 A CA2878344 A CA 2878344A CA 2878344 A1 CA2878344 A1 CA 2878344A1
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- Prior art keywords
- hcmv
- seq
- membrane protein
- complex
- protein complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16151—Methods of production or purification of viral material
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261668975P | 2012-07-06 | 2012-07-06 | |
| US61/668,975 | 2012-07-06 | ||
| US201361770257P | 2013-02-27 | 2013-02-27 | |
| US61/770,257 | 2013-02-27 | ||
| PCT/EP2013/063750 WO2014005959A1 (en) | 2012-07-06 | 2013-06-29 | Complexes of cytomegalovirus proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2878344A1 true CA2878344A1 (en) | 2014-01-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2878344A Abandoned CA2878344A1 (en) | 2012-07-06 | 2013-06-29 | Complexes of cytomegalovirus proteins |
Country Status (17)
Families Citing this family (33)
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| GB2513768B (en) | 2012-07-06 | 2015-04-15 | Novartis Ag | Complexes of cytomegalovirus proteins and nucleic acids encoding such proteins |
| CN104838000B (zh) | 2012-07-27 | 2022-12-20 | 希望之城 | 一种递送ul128复合体和预防cmv感染的mva疫苗 |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| ES2868427T3 (es) * | 2013-12-03 | 2021-10-21 | Hookipa Biotech Ag | Vacunas contra el CMV |
| AU2015251221A1 (en) * | 2014-04-23 | 2016-10-27 | CARIPLO, Fondazione | Human cytomegalovirus vaccine compositions and method of producing the same |
| WO2015165480A1 (en) * | 2014-04-30 | 2015-11-05 | Institute For Research In Biomedicine | Human cytomegalovirus vaccine compositions and method of producing the same |
| PE20170301A1 (es) * | 2014-05-08 | 2017-03-30 | Pfizer | Medios y metodos para el tratamiento cmv |
| EP3015475A1 (en) | 2014-10-31 | 2016-05-04 | Novartis AG | Mammalian cells expressing cytomegalovirus antigens |
| EP3048114A1 (en) * | 2015-01-22 | 2016-07-27 | Novartis AG | Cytomegalovirus antigens and uses thereof |
| EP3047856A1 (en) * | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv antigens and uses thereof |
| EP3347045A4 (en) | 2015-09-10 | 2019-08-28 | City of Hope | MVA-GH / GL-PC VACCINATED ANTIBODIES FOR NEUTRALIZING THE INFECTIOSITY OF HUMAN CYTOMEGALOVIRUS AND METHOD THEREFOR |
| JP6921833B2 (ja) * | 2015-10-22 | 2021-08-18 | モデルナティーエックス， インコーポレイテッド | ヒトサイトメガロウイルスワクチン |
| CN113181106A (zh) | 2016-01-11 | 2021-07-30 | 沃达瑞公司 | 微针组合物及其使用方法 |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EP3528821A4 (en) | 2016-10-21 | 2020-07-01 | ModernaTX, Inc. | HUMAN CYTOMEGALOVIRUS VACCINE |
| JP2020515522A (ja) * | 2017-01-27 | 2020-05-28 | ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | 免疫応答を誘導するヘルペスウイルスエンベロープタンパク質の組み合わせのワクチン組成物 |
| WO2018187325A1 (en) | 2017-04-04 | 2018-10-11 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| US20230248820A1 (en) | 2017-04-19 | 2023-08-10 | Glaxosmithkline Biologicals, S.A. | Modified cytomegalovirus proteins and stabilized complexes |
| EP3658581A1 (en) * | 2017-07-24 | 2020-06-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies and peptides to treat hcmv related diseases |
| IL272281B2 (en) | 2017-07-28 | 2023-04-01 | Janssen Vaccines Prevention B V | Methods and preparations for heterologous reprna vaccines |
| AU2018331874B2 (en) | 2017-09-13 | 2022-06-02 | Sanofi Pasteur | Human cytomegalovirus immunogenic composition |
| EP3758747A1 (en) * | 2018-02-28 | 2021-01-06 | University of Washington | Self-asssembling nanostructure vaccines |
| IL278418B2 (en) | 2018-05-04 | 2024-01-01 | Spybiotech Ltd | Vaccine composition |
| JP7584405B2 (ja) * | 2018-10-17 | 2024-11-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変されたサイトメガロウイルスタンパク質及び安定化された複合体 |
| AU2019397719B2 (en) | 2018-12-10 | 2023-11-09 | Km Biologics Co., Ltd. | Vaccine for preventing or treating congenital infection with cytomegalovirus |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EP4004018A1 (en) | 2019-07-24 | 2022-06-01 | GlaxoSmithKline Biologicals SA | Modified human cytomegalovirus proteins |
| KR102837045B1 (ko) * | 2020-06-09 | 2025-07-23 | 케이엠 바이올로직스 가부시키가이샤 | 사이토메갈로바이러스의 gB와 펜타머의 융합 단백질 및 당해 융합 단백질을 포함하는 백신 |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| AU2021367917A1 (en) | 2020-10-28 | 2023-06-22 | Sanofi Pasteur | Liposomes containing tlr4 agonist, preparation and uses thereof |
| PE20240083A1 (es) * | 2021-02-24 | 2024-01-16 | Pfizer | Nuevas regiones modulables farmacologicamente en el polipeptido de la glicoproteina b del citomegalovirus humano y metodos de uso de las mismas |
| US20250101067A1 (en) | 2022-01-28 | 2025-03-27 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
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|---|---|---|---|---|
| EP1201757A3 (en) | 1988-12-22 | 2002-09-11 | Genentech, Inc. | Method for preparing water soluble polypeptides |
| US5364780A (en) | 1989-03-17 | 1994-11-15 | E. I. Du Pont De Nemours And Company | External regulation of gene expression by inducible promoters |
| WO1992002628A1 (en) | 1990-08-02 | 1992-02-20 | Chiron Corporation | Expression of human cmv glycoprotein-h using the baculovirus-insect cell expression system |
| US5474914A (en) * | 1992-07-29 | 1995-12-12 | Chiron Corporation | Method of producing secreted CMV glycoprotein H |
| US5362865A (en) | 1993-09-02 | 1994-11-08 | Monsanto Company | Enhanced expression in plants using non-translated leader sequences |
| US5693506A (en) | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US5815900A (en) | 1995-03-06 | 1998-10-06 | Matsushita Electric Industrial Co., Ltd. | Method of manufacturing a surface acoustic wave module |
| WO2004076645A2 (en) * | 2003-02-27 | 2004-09-10 | University Of Massachusetts | Compositions and methods for cytomegalovirus treatment |
| JP5822433B2 (ja) | 2006-06-07 | 2015-11-24 | ザ・トラスティーズ・オブ・プリンストン・ユニバーシティＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｐｒｉｎｃｅｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ | ワクチン中に薬剤標的として用いるサイトメガロウイルス表面タンパク質複合体 |
| US7947274B2 (en) * | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
| US9439960B2 (en) | 2007-10-10 | 2016-09-13 | The Trustees Of Princeton University | Cytomegalovirus vaccines and methods of production |
| EA026401B1 (ru) | 2009-09-02 | 2017-04-28 | Новартис Аг | Иммуногенные композиции, содержащие модуляторы активности tlr |
| US9089537B2 (en) * | 2010-02-26 | 2015-07-28 | The Trustees Of The University Of Pennslyvania | Subunit vaccines for herpes viruses and methods of use |
| CA2804591C (en) | 2010-07-06 | 2019-01-22 | Novartis Ag | Cationic oil-in-water emulsions |
| PL2590626T3 (pl) | 2010-07-06 | 2016-04-29 | Glaxosmithkline Biologicals Sa | Liposomy z lipidami o korzystnej wartości pka do dostarczania rna |
| WO2012015211A2 (ko) | 2010-07-30 | 2012-02-02 | 주식회사종근당 | 사이클로스포린 에이 함유 점안제 조성물 |
| EP2614072A4 (en) * | 2010-09-09 | 2014-03-19 | Univ Virginia Commonwealth | VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS |
| BR112013008700B8 (pt) | 2010-10-11 | 2022-10-04 | Novartis Ag | Molécula de rna auto-replicante, partícula de replicon de alfavírus, composição, molécula de dna recombinante, uso da molécula de rna auto-replicante |
| MX352974B (es) * | 2011-01-31 | 2017-12-15 | Univ Pennsylvania | Moleculas de acido nucleico que codifican novedosos antigenos de herpes, vacunas que las comprenden y metodos para su uso. |
| US11058762B2 (en) | 2011-07-06 | 2021-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic compositions and uses thereof |
| MX350258B (es) * | 2011-07-06 | 2017-08-31 | Novartis Ag | Emulsiones cationicas de aceite en agua. |
| PT2750707T (pt) * | 2011-08-31 | 2019-01-23 | Glaxosmithkline Biologicals Sa | Lipossomas peguilados para distribuição de arn que codifica imunogénio |
| GB2513768B (en) | 2012-07-06 | 2015-04-15 | Novartis Ag | Complexes of cytomegalovirus proteins and nucleic acids encoding such proteins |
| EP3015475A1 (en) | 2014-10-31 | 2016-05-04 | Novartis AG | Mammalian cells expressing cytomegalovirus antigens |
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2013
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- 2013-06-29 JP JP2015519155A patent/JP2015522581A/ja active Pending
- 2013-06-29 KR KR1020157002267A patent/KR20150031322A/ko not_active Withdrawn
- 2013-06-29 AU AU2013286093A patent/AU2013286093B2/en not_active Ceased
- 2013-06-29 MX MX2014015496A patent/MX355469B/es active IP Right Grant
- 2013-06-29 SG SG11201408328VA patent/SG11201408328VA/en unknown
- 2013-06-29 CN CN201380036145.0A patent/CN104853771A/zh active Pending
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- 2013-06-29 HK HK15110880.5A patent/HK1210037A1/xx unknown
- 2013-06-29 WO PCT/EP2013/063750 patent/WO2014005959A1/en not_active Ceased
- 2013-06-29 CA CA2878344A patent/CA2878344A1/en not_active Abandoned
- 2013-06-29 IN IN2929KON2014 patent/IN2014KN02929A/en unknown
- 2013-06-29 US US14/410,461 patent/US9683022B2/en active Active
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- 2013-06-29 MX MX2018000675A patent/MX378747B/es unknown
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2014
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2019
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2021
- 2021-12-15 US US17/551,867 patent/US20220106364A1/en not_active Abandoned
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| MX2014015496A (es) | 2015-03-06 |
| JP2017192400A (ja) | 2017-10-26 |
| WO2014005959A1 (en) | 2014-01-09 |
| ZA201409364B (en) | 2017-08-30 |
| GB201413863D0 (en) | 2014-09-17 |
| RU2015103891A (ru) | 2016-08-27 |
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| JP2017192399A (ja) | 2017-10-26 |
| SG11201408328VA (en) | 2015-02-27 |
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| US20170320916A1 (en) | 2017-11-09 |
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| US20190211064A1 (en) | 2019-07-11 |
| EP2869843A1 (en) | 2015-05-13 |
| HK1210037A1 (en) | 2016-04-15 |
| ES2753138T3 (es) | 2020-04-07 |
| CN104853771A (zh) | 2015-08-19 |
| EP2869843B1 (en) | 2019-08-07 |
| AU2013286093B2 (en) | 2018-01-04 |
| US20160159864A1 (en) | 2016-06-09 |
| IL236261A0 (en) | 2015-02-26 |
| US10287322B2 (en) | 2019-05-14 |
| JP2015522581A (ja) | 2015-08-06 |
| AU2013286093A1 (en) | 2015-02-12 |
| MX355469B (es) | 2018-04-19 |
| US20220106364A1 (en) | 2022-04-07 |
| GB2513768B (en) | 2015-04-15 |
| KR20150031322A (ko) | 2015-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190702 |