AU2012282402B2 - Antibodies to phosphorylated tau aggregates - Google Patents
Antibodies to phosphorylated tau aggregates Download PDFInfo
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- AU2012282402B2 AU2012282402B2 AU2012282402A AU2012282402A AU2012282402B2 AU 2012282402 B2 AU2012282402 B2 AU 2012282402B2 AU 2012282402 A AU2012282402 A AU 2012282402A AU 2012282402 A AU2012282402 A AU 2012282402A AU 2012282402 B2 AU2012282402 B2 AU 2012282402B2
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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Landscapes
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| NZ703423A (en) | 2012-07-03 | 2018-02-23 | Univ Washington | Antibodies to tau |
| SG10201701181XA (en) * | 2012-08-16 | 2017-04-27 | Ipierian Inc | Methods of treating a tauopathy |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| CU24446B1 (es) | 2013-03-13 | 2019-10-04 | Prothena Biosciences Ltd | Un anticuerpo monoclonal humanizado que se une a tau |
| EA039554B1 (ru) * | 2013-06-10 | 2022-02-09 | АйПИЕРИАН, ИНК. | Способ снижения уровней a40 и/или a42 в нервной клетке и/или во внеклеточной жидкости |
| JP6629201B2 (ja) * | 2013-11-27 | 2020-01-15 | アイピエリアン，インコーポレイティド | タウオパチーの処置方法 |
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| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン，インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| AR100978A1 (es) | 2014-06-26 | 2016-11-16 | Hoffmann La Roche | LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS |
| TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商Ｃ２Ｎ醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| MX371295B (es) | 2014-10-08 | 2020-01-24 | Texas Childrens Hospital | Formación de imágenes por irm de placas amiloides usando liposomas. |
| WO2016055941A1 (en) * | 2014-10-10 | 2016-04-14 | National Research Council Of Canada | Anti-tau antibody and uses thereof |
| AR103713A1 (es) | 2015-02-26 | 2017-05-31 | Lilly Co Eli | Anticuerpos contra tau y sus usos |
| NZ737796A (en) * | 2015-06-05 | 2025-02-28 | Genentech Inc | Anti-tau antibodies and methods of use |
| JP6619460B2 (ja) | 2015-06-24 | 2019-12-11 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ヒト化抗タウ（ｐＳ４２２）抗体及び使用法 |
| MX2017015908A (es) | 2015-07-06 | 2018-03-15 | Ucb Biopharma Sprl | Anticuerpos de union a tau. |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| US10752679B2 (en) | 2016-05-02 | 2020-08-25 | Prothena Biosciences Limited | Tau immunotherapy |
| EA201892417A1 (ru) | 2016-05-02 | 2019-05-31 | Протена Биосайенсис Лимитед | Антитела, распознающие тау |
| AU2017259039B2 (en) | 2016-05-02 | 2024-05-09 | Prothena Biosciences Limited | Antibodies recognizing tau |
| CA3030754C (en) * | 2016-07-20 | 2022-04-26 | Anahit Ghochikyan | Humanized anti-tau antibodies and compositions for and methods of making and using in treatment, diagnosis and monitoring of tauopathies |
| US10988529B2 (en) | 2016-08-09 | 2021-04-27 | Eli Lilly And Company | Combination therapy |
| KR101876423B1 (ko) | 2016-10-10 | 2018-07-09 | 한국과학기술연구원 | 치매 모델 형질전환 마우스 및 이를 이용한 스크리닝 방법 |
| FR3058143B1 (fr) * | 2016-10-27 | 2021-03-12 | Univ Grenoble Alpes | Nanocorps anti-tau |
| EP3551220B1 (en) | 2016-12-07 | 2025-01-29 | Genentech, Inc. | Anti-tau antibodies and methods of use |
| JP2020511937A (ja) | 2016-12-07 | 2020-04-23 | ジェネンテック， インコーポレイテッド | 抗ｔａｕ抗体及び使用方法 |
| US10364286B2 (en) * | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| MX2019009817A (es) | 2017-02-17 | 2019-11-21 | Denali Therapeutics Inc | Anticuerpos anti-tau y metodos de uso de los mismos. |
| CN110881274B (zh) | 2017-05-02 | 2024-11-15 | 普罗塞纳生物科学有限公司 | 识别tau的抗体 |
| PE20210115A1 (es) | 2017-10-16 | 2021-01-19 | Eisai Randd Man Co Ltd | Anticuerpos anti-tau y uso de los mismos |
| IL302108A (en) * | 2017-10-25 | 2023-06-01 | Ac Immune Sa | Preparations of phosphorylated tau peptides and uses thereof |
| AU2019232631A1 (en) | 2018-03-05 | 2020-09-24 | Janssen Pharmaceutica Nv | Anti-PHF-tau antibodies and uses thereof |
| US10591492B2 (en) * | 2018-03-05 | 2020-03-17 | Janssen Pharmaceutica Nv | Assays to detect neurodegeneration |
| JP2021530552A (ja) | 2018-07-31 | 2021-11-11 | イーライ リリー アンド カンパニー | 併用療法 |
| JP7594913B2 (ja) * | 2018-11-22 | 2024-12-05 | 富士レビオ株式会社 | 抗体コンジュゲート |
| WO2020120644A1 (en) * | 2018-12-13 | 2020-06-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New anti tau svqivykpv epitope single domain antibody |
| JP7630834B2 (ja) | 2019-03-03 | 2025-02-18 | プロセナ バイオサイエンシーズ リミテッド | タウ認識抗体 |
| JP2024534348A (ja) | 2021-09-09 | 2024-09-20 | アルツパス， インコーポレイテッド | ホスホ－タウ抗体および使用の方法 |
| CN119661705B (zh) * | 2024-11-22 | 2025-06-24 | 上海伯杰医疗科技股份有限公司 | 一种抗p-Tau217蛋白单克隆抗体及其制备方法和应用 |
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Also Published As
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|---|---|
| US20140161875A1 (en) | 2014-06-12 |
| AU2012282402A1 (en) | 2014-01-30 |
| US9447179B2 (en) | 2016-09-20 |
| GB201112056D0 (en) | 2011-08-31 |
| WO2013007839A1 (en) | 2013-01-17 |
| JP2014523742A (ja) | 2014-09-18 |
| JP6168364B2 (ja) | 2017-07-26 |
| EP2731969A1 (en) | 2014-05-21 |
| AU2012282402A2 (en) | 2014-05-08 |
| EP2731969B1 (en) | 2018-10-17 |
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