AU2012268078B2 - Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived Factor-1 - Google Patents
Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived Factor-1 Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
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| WO2011106234A1 (en) | 2010-02-25 | 2011-09-01 | Provasculon, Inc. | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| JP6145089B2 (ja) | 2011-06-07 | 2017-06-07 | メソブラスト インターナショナル エスエイアールエル | ストロマ細胞由来因子−１のプロテアーゼ耐性変異体を用いた、組織損傷を修復するための方法 |
| KR20160096640A (ko) * | 2013-12-13 | 2016-08-16 | 메조블라스트 인터내셔널 에스에이알엘 | 기질 세포 유래 인자-1의 프로테아제-내성 돌연변이를 사용한 조직 손상의 복구 방법 |
| JP6532141B2 (ja) * | 2014-09-26 | 2019-06-19 | ヘリックスミス カンパニー リミテッド | 肝細胞増殖因子及びストローマ細胞由来因子１αを用いた末梢動脈疾患の予防または治療用組成物 |
| CN114366806A (zh) * | 2021-12-16 | 2022-04-19 | 天津市泌尿外科研究所 | 一种纳米黑磷负载sdf-1的纳米药物复合体及其制备方法和应用 |
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| US20070172811A1 (en) * | 2006-01-20 | 2007-07-26 | Board Of Regents, The University Of Texas System | Preserving hypoxic tissue |
| US20080095758A1 (en) * | 2006-10-23 | 2008-04-24 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| US20080253996A1 (en) * | 2005-10-31 | 2008-10-16 | Laboratories Serono Sa | Use of Sdf-1 for the Treatment and/or Prevention of Neurological Diseases |
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| JPWO2010024300A1 (ja) | 2008-08-26 | 2012-01-26 | 国立大学法人北海道大学 | 骨充填型軟骨組織再生誘導剤 |
| AU2010249482A1 (en) | 2009-05-20 | 2012-01-12 | Board Of Regents, The University Of Texas System | Identification of micro-RNAs involved in post-myocardial infarction remodeling and heart failure |
| WO2010138180A2 (en) * | 2009-05-26 | 2010-12-02 | The University Of Vermont And State Agriculture College | Compositions and methods for cardiac tissue repair |
| WO2011106234A1 (en) * | 2010-02-25 | 2011-09-01 | Provasculon, Inc. | Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| WO2012027170A1 (en) * | 2010-08-23 | 2012-03-01 | Provasculon, Inc. | Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1 |
| WO2012026041A1 (ja) * | 2010-08-27 | 2012-03-01 | 富士通株式会社 | 並列計算機、並列計算機のジョブ情報取得プログラム、並列計算機のジョブ情報取得方法、計算装置及び計算管理装置 |
| JP6145089B2 (ja) | 2011-06-07 | 2017-06-07 | メソブラスト インターナショナル エスエイアールエル | ストロマ細胞由来因子−１のプロテアーゼ耐性変異体を用いた、組織損傷を修復するための方法 |
| KR20160096640A (ko) | 2013-12-13 | 2016-08-16 | 메조블라스트 인터내셔널 에스에이알엘 | 기질 세포 유래 인자-1의 프로테아제-내성 돌연변이를 사용한 조직 손상의 복구 방법 |
-
2012
- 2012-06-06 JP JP2014514581A patent/JP6145089B2/ja not_active Expired - Fee Related
- 2012-06-06 CN CN201280037907.4A patent/CN103747795A/zh active Pending
- 2012-06-06 CA CA2838155A patent/CA2838155C/en active Active
- 2012-06-06 EP EP12796309.8A patent/EP2717894B1/en not_active Not-in-force
- 2012-06-06 US US14/124,187 patent/US10662234B2/en not_active Expired - Fee Related
- 2012-06-06 WO PCT/US2012/041054 patent/WO2012170495A1/en not_active Ceased
- 2012-06-06 AU AU2012268078A patent/AU2012268078B2/en not_active Ceased
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2013
- 2013-11-28 IL IL229697A patent/IL229697A0/en unknown
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2017
- 2017-01-27 JP JP2017013060A patent/JP2017114867A/ja active Pending
- 2017-08-08 AU AU2017213440A patent/AU2017213440A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080253996A1 (en) * | 2005-10-31 | 2008-10-16 | Laboratories Serono Sa | Use of Sdf-1 for the Treatment and/or Prevention of Neurological Diseases |
| US20070172811A1 (en) * | 2006-01-20 | 2007-07-26 | Board Of Regents, The University Of Texas System | Preserving hypoxic tissue |
| US20080095758A1 (en) * | 2006-10-23 | 2008-04-24 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
| US7696309B2 (en) * | 2006-10-23 | 2010-04-13 | The Brigham And Women's Hospital, Inc. | Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage |
Also Published As
| Publication number | Publication date |
|---|---|
| IL229697A0 (en) | 2014-01-30 |
| EP2717894B1 (en) | 2018-01-24 |
| US20140199304A1 (en) | 2014-07-17 |
| AU2017213440A1 (en) | 2017-08-24 |
| JP2017114867A (ja) | 2017-06-29 |
| JP6145089B2 (ja) | 2017-06-07 |
| EP2717894A4 (en) | 2015-02-25 |
| CA2838155A1 (en) | 2012-12-13 |
| CN103747795A (zh) | 2014-04-23 |
| US10662234B2 (en) | 2020-05-26 |
| AU2012268078A1 (en) | 2013-12-19 |
| CA2838155C (en) | 2021-10-19 |
| EP2717894A1 (en) | 2014-04-16 |
| JP2014519514A (ja) | 2014-08-14 |
| WO2012170495A1 (en) | 2012-12-13 |
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