AU2010220058B2 - Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome - Google Patents
Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome Download PDFInfo
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- AU2010220058B2 AU2010220058B2 AU2010220058A AU2010220058A AU2010220058B2 AU 2010220058 B2 AU2010220058 B2 AU 2010220058B2 AU 2010220058 A AU2010220058 A AU 2010220058A AU 2010220058 A AU2010220058 A AU 2010220058A AU 2010220058 B2 AU2010220058 B2 AU 2010220058B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Zoology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN224/CHE/2009 | 2009-02-02 | ||
| IN224CH2009 | 2009-02-02 | ||
| PCT/IN2010/000053 WO2010100653A2 (en) | 2009-02-02 | 2010-02-01 | Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2010220058A1 AU2010220058A1 (en) | 2011-07-21 |
| AU2010220058B2 true AU2010220058B2 (en) | 2016-02-18 |
Family
ID=42710066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2010220058A Active AU2010220058B2 (en) | 2009-02-02 | 2010-02-01 | Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US9241964B2 (https=) |
| EP (1) | EP2391374B1 (https=) |
| JP (1) | JP2012516842A (https=) |
| KR (1) | KR101682489B1 (https=) |
| CN (1) | CN102292093B (https=) |
| AU (1) | AU2010220058B2 (https=) |
| CA (1) | CA2751227C (https=) |
| WO (1) | WO2010100653A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| ME01898B (me) | 2008-08-12 | 2014-12-20 | Zinfandel Pharmaceuticals Inc | Metoda za identifikaciju faktora rizika od alchajmerove bolesti |
| JP2011079752A (ja) * | 2009-10-05 | 2011-04-21 | Kracie Home Products Ltd | 膵リパーゼ阻害剤並びにそれを含有する飲食品組成物及び医薬品組成物 |
| PH12013500451A1 (en) * | 2010-09-11 | 2013-05-20 | Laila Nutraceuticals | Sphaeranthus indicus derived ingredients and their compositions for enhancing physical performance and energy levels |
| JP5976271B2 (ja) * | 2010-12-24 | 2016-08-23 | クラシエホームプロダクツ株式会社 | リパーゼ阻害剤並びにそれを含有する化粧料、飲食品組成物及び医薬品組成物 |
| AU2012205798B2 (en) | 2011-01-10 | 2016-02-25 | Takeda Pharmaceutical Company Limited | Methods and drug products for treating Alzheimer's disease |
| KR101508294B1 (ko) * | 2012-07-05 | 2015-04-07 | 동국대학교 산학협력단 | 망고스틴 추출물 또는 감마, 알파 망고스틴을 유효성분으로 포함하는 c형 간염의 예방 또는 치료용 조성물 |
| JP2014034562A (ja) * | 2012-08-10 | 2014-02-24 | Lotte Kenko Sangyo:Kk | アディポネクチン産生促進剤 |
| WO2014064609A2 (en) * | 2012-10-23 | 2014-05-01 | Piramal Enterprises Limited | HERBAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF TNF-α MEDIATED DISEASES |
| US20140377386A1 (en) * | 2013-06-19 | 2014-12-25 | Access Business Group International Llc | Plant-based inhibitors of ketohexokinase for the support of weight management |
| JP6511604B2 (ja) * | 2013-07-10 | 2019-05-15 | 和久 前田 | メタボリックシンドローム治療剤の製造方法 |
| CN106361784B (zh) * | 2015-07-24 | 2020-08-14 | 山酮新药开发股份有限公司 | 山竹果果壳萃取物用于治疗皮肤疾病的用途 |
| TWI565472B (zh) * | 2016-02-02 | 2017-01-11 | 基業生物科技股份有限公司 | 山竹組合物及其製備增進阿茲海默症患者學習能力與記憶的藥物及保健食品之用途 |
| BR112018073483B1 (pt) * | 2016-05-21 | 2022-08-23 | Laila Impex | Suplementos e composições dietéticas para a melhoria do desempenho físico e dos níveis de energia |
| CN111773208A (zh) * | 2019-09-20 | 2020-10-16 | 厦门医学院 | 藤黄属果实萃取物γ-倒捻子素在制备降血糖及降血压的药物组合物中的应用 |
| CN111758967B (zh) * | 2020-07-15 | 2022-10-11 | 张兆熙 | 一种大鲵胶原蛋白肽组合物及其应用 |
| CN118873430B (zh) * | 2024-08-16 | 2025-04-04 | 诺德溯源(广州)生物科技有限公司 | 一种敏感肌适用的植物a醇祛皱紧致组合物及其应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1284134A2 (en) * | 2000-05-26 | 2003-02-19 | Shiseido Company Limited | External skin preparations for suppressing sebum secretion |
| WO2007036900A2 (en) * | 2005-09-30 | 2007-04-05 | Piramal Life Sciences Limited | Herbal composition for inflammatory disorders |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3647054B2 (ja) * | 1993-11-12 | 2005-05-11 | 御木本製薬株式会社 | 抗酸化剤 |
| JPH09110688A (ja) * | 1995-10-13 | 1997-04-28 | Meiji Milk Prod Co Ltd | 抗菌剤 |
| FR2774905B1 (fr) * | 1998-02-17 | 2000-06-09 | Codif International Sa | Utilisation d'une composition cosmetique comportant au moins une substance qui comprend un groupement pyrone |
| GB9921229D0 (en) * | 1999-09-08 | 1999-11-10 | Med Eq As | Compositions |
| DE60309075D1 (de) * | 2003-03-31 | 2006-11-23 | Council Scient Ind Res | Verfahren zur herstellung hypoglykämischer lebensmittel und formulierungen daraus |
| ES2559777T3 (es) * | 2004-03-17 | 2016-02-15 | Nestec S.A. | Composiciones y métodos para reducir o prevenir la obesidad |
| JP4247154B2 (ja) * | 2004-03-18 | 2009-04-02 | 有限会社 坂本薬草園 | PPARγ活性化剤 |
| JP5140231B2 (ja) * | 2004-04-08 | 2013-02-06 | 株式会社ロッテ | IκBキナーゼ阻害剤 |
| WO2006134609A2 (en) * | 2005-06-16 | 2006-12-21 | Mmi Corporation | Novel anticancer agent, methods for obtaining the same and pharmaceutical compositions thereof |
| SI1931366T1 (sl) * | 2005-09-30 | 2013-10-30 | Piramal Enterprises Limited | Zeliščni sestavek proti vnetnim motnjam |
| FR2908310B1 (fr) | 2006-11-14 | 2009-07-10 | Phytodia | Produits agonistes de tgr5 et leurs applications |
| WO2008093848A1 (ja) | 2007-02-02 | 2008-08-07 | Sunstar Inc. | ホスファチジルコリンを含有する炎症マーカー低減組成物 |
-
2010
- 2010-02-01 CA CA2751227A patent/CA2751227C/en active Active
- 2010-02-01 US US13/146,965 patent/US9241964B2/en active Active
- 2010-02-01 EP EP10748413.1A patent/EP2391374B1/en active Active
- 2010-02-01 WO PCT/IN2010/000053 patent/WO2010100653A2/en not_active Ceased
- 2010-02-01 KR KR1020117020360A patent/KR101682489B1/ko active Active
- 2010-02-01 CN CN201080004917.9A patent/CN102292093B/zh active Active
- 2010-02-01 AU AU2010220058A patent/AU2010220058B2/en active Active
- 2010-02-01 JP JP2011547063A patent/JP2012516842A/ja active Pending
-
2013
- 2013-01-28 US US13/752,181 patent/US20130136809A1/en not_active Abandoned
-
2015
- 2015-11-24 US US14/951,175 patent/US10471114B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1284134A2 (en) * | 2000-05-26 | 2003-02-19 | Shiseido Company Limited | External skin preparations for suppressing sebum secretion |
| US20060057229A1 (en) * | 2000-05-26 | 2006-03-16 | Shiseido Company, Ltd. | External skin preparations for suppressing sebum secretion |
| WO2007036900A2 (en) * | 2005-09-30 | 2007-04-05 | Piramal Life Sciences Limited | Herbal composition for inflammatory disorders |
| US20080254157A1 (en) * | 2005-09-30 | 2008-10-16 | Piramal Life Sciences Limited | Herbal composition for inflammatory disorders |
Non-Patent Citations (3)
| Title |
|---|
| BAFNA, A.R. et al: "Immunomodulatory Activity Of Methanol Extract Of Flower-Heads Of Sphaeranthus Indicus Linn", Ars Pharmaceutica, vol. 45, no. 3, January 2004, pages 281-291 * |
| PEDRAZA-CHAVERRI J. et al: "Medicinal properties of mangosteen (Garcinia mangostana)", Food And Chemical Toxicology, vol. 46, October 2008, pages 3227-3239 * |
| SHIRWAIKAR, A. et al., "In vitro antioxidant studies of Sphaeranthus indicus (Linn)", Indian Journal Of Experimental Biology, 1 December 2006, pages 993-996 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US10471114B2 (en) | 2019-11-12 |
| CA2751227A1 (en) | 2010-09-10 |
| EP2391374A4 (en) | 2014-01-08 |
| EP2391374A2 (en) | 2011-12-07 |
| JP2012516842A (ja) | 2012-07-26 |
| WO2010100653A8 (en) | 2011-08-04 |
| KR20110122158A (ko) | 2011-11-09 |
| US9241964B2 (en) | 2016-01-26 |
| EP2391374B1 (en) | 2018-11-14 |
| US20130136809A1 (en) | 2013-05-30 |
| CN102292093B (zh) | 2015-01-28 |
| CN102292093A (zh) | 2011-12-21 |
| AU2010220058A1 (en) | 2011-07-21 |
| KR101682489B1 (ko) | 2016-12-05 |
| WO2010100653A3 (en) | 2010-11-04 |
| US20160074457A1 (en) | 2016-03-17 |
| WO2010100653A2 (en) | 2010-09-10 |
| US20110280951A1 (en) | 2011-11-17 |
| CA2751227C (en) | 2021-10-26 |
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