CA2751227C - Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome - Google Patents

Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome Download PDF

Info

Publication number
CA2751227C
CA2751227C CA2751227A CA2751227A CA2751227C CA 2751227 C CA2751227 C CA 2751227C CA 2751227 A CA2751227 A CA 2751227A CA 2751227 A CA2751227 A CA 2751227A CA 2751227 C CA2751227 C CA 2751227C
Authority
CA
Canada
Prior art keywords
composition
control
metabolic syndrome
garcinia mangostana
sphaeranthus indicus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2751227A
Other languages
English (en)
French (fr)
Other versions
CA2751227A1 (en
Inventor
Ganga Raju Gokaraju
Rama Raju Gokaraju
Venkata Kanaka Ranga Raju Gokaraju
Trimurtulu Golakoti
Kiran Bhupathiraju
Krishanu Sengupta
Venkata Krishna Raju Alluri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laila Nutraceuticals
Original Assignee
Laila Nutraceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laila Nutraceuticals filed Critical Laila Nutraceuticals
Publication of CA2751227A1 publication Critical patent/CA2751227A1/en
Application granted granted Critical
Publication of CA2751227C publication Critical patent/CA2751227C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
CA2751227A 2009-02-02 2010-02-01 Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome Active CA2751227C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN224/CHE/2009 2009-02-02
IN224CH2009 2009-02-02
PCT/IN2010/000053 WO2010100653A2 (en) 2009-02-02 2010-02-01 Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome

Publications (2)

Publication Number Publication Date
CA2751227A1 CA2751227A1 (en) 2010-09-10
CA2751227C true CA2751227C (en) 2021-10-26

Family

ID=42710066

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2751227A Active CA2751227C (en) 2009-02-02 2010-02-01 Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome

Country Status (8)

Country Link
US (3) US9241964B2 (https=)
EP (1) EP2391374B1 (https=)
JP (1) JP2012516842A (https=)
KR (1) KR101682489B1 (https=)
CN (1) CN102292093B (https=)
AU (1) AU2010220058B2 (https=)
CA (1) CA2751227C (https=)
WO (1) WO2010100653A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8846315B2 (en) 2008-08-12 2014-09-30 Zinfandel Pharmaceuticals, Inc. Disease risk factors and methods of use
ME01898B (me) 2008-08-12 2014-12-20 Zinfandel Pharmaceuticals Inc Metoda za identifikaciju faktora rizika od alchajmerove bolesti
JP2011079752A (ja) * 2009-10-05 2011-04-21 Kracie Home Products Ltd 膵リパーゼ阻害剤並びにそれを含有する飲食品組成物及び医薬品組成物
PH12013500451A1 (en) * 2010-09-11 2013-05-20 Laila Nutraceuticals Sphaeranthus indicus derived ingredients and their compositions for enhancing physical performance and energy levels
JP5976271B2 (ja) * 2010-12-24 2016-08-23 クラシエホームプロダクツ株式会社 リパーゼ阻害剤並びにそれを含有する化粧料、飲食品組成物及び医薬品組成物
AU2012205798B2 (en) 2011-01-10 2016-02-25 Takeda Pharmaceutical Company Limited Methods and drug products for treating Alzheimer's disease
KR101508294B1 (ko) * 2012-07-05 2015-04-07 동국대학교 산학협력단 망고스틴 추출물 또는 감마, 알파 망고스틴을 유효성분으로 포함하는 ｃ형 간염의 예방 또는 치료용 조성물
JP2014034562A (ja) * 2012-08-10 2014-02-24 Lotte Kenko Sangyo:Kk アディポネクチン産生促進剤
WO2014064609A2 (en) * 2012-10-23 2014-05-01 Piramal Enterprises Limited HERBAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF TNF-α MEDIATED DISEASES
US20140377386A1 (en) * 2013-06-19 2014-12-25 Access Business Group International Llc Plant-based inhibitors of ketohexokinase for the support of weight management
JP6511604B2 (ja) * 2013-07-10 2019-05-15 和久 前田 メタボリックシンドローム治療剤の製造方法
CN106361784B (zh) * 2015-07-24 2020-08-14 山酮新药开发股份有限公司 山竹果果壳萃取物用于治疗皮肤疾病的用途
TWI565472B (zh) * 2016-02-02 2017-01-11 基業生物科技股份有限公司 山竹組合物及其製備增進阿茲海默症患者學習能力與記憶的藥物及保健食品之用途
BR112018073483B1 (pt) * 2016-05-21 2022-08-23 Laila Impex Suplementos e composições dietéticas para a melhoria do desempenho físico e dos níveis de energia
CN111773208A (zh) * 2019-09-20 2020-10-16 厦门医学院 藤黄属果实萃取物γ-倒捻子素在制备降血糖及降血压的药物组合物中的应用
CN111758967B (zh) * 2020-07-15 2022-10-11 张兆熙 一种大鲵胶原蛋白肽组合物及其应用
CN118873430B (zh) * 2024-08-16 2025-04-04 诺德溯源(广州)生物科技有限公司 一种敏感肌适用的植物a醇祛皱紧致组合物及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3647054B2 (ja) * 1993-11-12 2005-05-11 御木本製薬株式会社 抗酸化剤
JPH09110688A (ja) * 1995-10-13 1997-04-28 Meiji Milk Prod Co Ltd 抗菌剤
FR2774905B1 (fr) * 1998-02-17 2000-06-09 Codif International Sa Utilisation d'une composition cosmetique comportant au moins une substance qui comprend un groupement pyrone
GB9921229D0 (en) * 1999-09-08 1999-11-10 Med Eq As Compositions
JP2002047125A (ja) * 2000-05-26 2002-02-12 Shiseido Co Ltd 皮脂分泌抑制用皮膚外用剤
DE60309075D1 (de) * 2003-03-31 2006-11-23 Council Scient Ind Res Verfahren zur herstellung hypoglykämischer lebensmittel und formulierungen daraus
ES2559777T3 (es) * 2004-03-17 2016-02-15 Nestec S.A. Composiciones y métodos para reducir o prevenir la obesidad
JP4247154B2 (ja) * 2004-03-18 2009-04-02 有限会社 坂本薬草園 ＰＰＡＲγ活性化剤
JP5140231B2 (ja) * 2004-04-08 2013-02-06 株式会社ロッテ ＩκＢキナーゼ阻害剤
WO2006134609A2 (en) * 2005-06-16 2006-12-21 Mmi Corporation Novel anticancer agent, methods for obtaining the same and pharmaceutical compositions thereof
SI1931366T1 (sl) * 2005-09-30 2013-10-30 Piramal Enterprises Limited Zeliščni sestavek proti vnetnim motnjam
EA014070B1 (ru) * 2005-09-30 2010-08-30 Пирамал Лайф Сайнсиз Лимитед Применение растительной композиции для лечения воспалительных нарушений
FR2908310B1 (fr) 2006-11-14 2009-07-10 Phytodia Produits agonistes de tgr5 et leurs applications
WO2008093848A1 (ja) 2007-02-02 2008-08-07 Sunstar Inc. ホスファチジルコリンを含有する炎症マーカー低減組成物

Also Published As

Publication number Publication date
US10471114B2 (en) 2019-11-12
CA2751227A1 (en) 2010-09-10
EP2391374A4 (en) 2014-01-08
EP2391374A2 (en) 2011-12-07
JP2012516842A (ja) 2012-07-26
WO2010100653A8 (en) 2011-08-04
KR20110122158A (ko) 2011-11-09
US9241964B2 (en) 2016-01-26
EP2391374B1 (en) 2018-11-14
US20130136809A1 (en) 2013-05-30
CN102292093B (zh) 2015-01-28
AU2010220058B2 (en) 2016-02-18
CN102292093A (zh) 2011-12-21
AU2010220058A1 (en) 2011-07-21
KR101682489B1 (ko) 2016-12-05
WO2010100653A3 (en) 2010-11-04
US20160074457A1 (en) 2016-03-17
WO2010100653A2 (en) 2010-09-10
US20110280951A1 (en) 2011-11-17

Similar Documents

Publication Publication Date Title
CA2751227C (en) Composition from sphaeranthus indicus and garcinia mangostana for the control of metabolic syndrome
WO2010146568A3 (en) Bifidobacteria for treating diabetes and related conditions
JP2007535575A (ja) 生物活性化合物およびその使用方法
PH12013500808A1 (en) Pharmaceutical combinations for the treatment of metabolic disorders
WO2008143182A1 (ja) 甘草ポリフェノールを含有する組成物
MX2010001560A (es) Composicion farmaceutica que comprende un inhibidor de sglt2 en combinacion con un inhibidor de dpp-iv.
WO2010030054A3 (en) Uses of sesquiterpene derivatives
WO2011018501A3 (en) Composition including an unsaponifiable fraction
BR112012005768A2 (pt) agente antiobesidade, bebida ou alimento antiobesidade, agente de melhoramento de tolerância à glicose, e alimento ou bebida para o melhoramento de tolerância à glicose
WO2011163319A3 (en) Activation of amp-protein activated kinase by oxaloacetate compounds
WO2012119078A3 (en) COMPOSITIONS AND METHODS COMPRISING C16:1n7-PALMITOLEATE
WO2011106423A3 (en) Acai and iridoid based formulations
WO2010136900A3 (en) Methods of using krill oil to treat risk factors for metabolic disorders and obesity
WO2011106448A3 (en) Iridoid based formulations
WO2011106417A3 (en) Garcinia mangostana l. and iridoid based formulations
WO2018108931A3 (en) Nutritional compositions containing butyrate and/or lactoferrin and uses thereof
WO2011043631A3 (ko) 호장근 추출물, 이의 분획물 또는 스틸벤계 화합물을 포함하는 감기의 예방 및 치료용 약학 조성물
WO2008123128A1 (ja) アディポネクチン産生促進剤
AbuKhader Thymoquinone: a promising antidiabetic agent
Van Der Spuy et al. Is the use of resveratrol in the treatment and prevention of obesity premature?
JP2011504921A5 (https=)
El-Shinnawi et al. Actions of adjunctive nutritional antioxidants in periodontitis and prevalent systemic inflammatory diseases
WO2011141113A3 (de) Kombination aus vitamin k und nikotinamid
WO2011126342A3 (ko) 대잎둥굴레 또는 층층갈고리둥굴레 추출물의 신규한 용도
Nadeem et al. Lagenaria siceraria fruit extract ameliorate fat amassment and serum TNF–in high–fat diet–induced obese rats

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150107

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - SMALL

Year of fee payment: 15

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250108

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20250108

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250108

R11 Change to the name of applicant or owner or transfer of ownership requested

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R11-R103 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CHANGE OF NAME REQUEST RECEIVED

Effective date: 20250516

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-4-4-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250516

R13 Change to the name of applicant or owner recorded

Free format text: ST27 STATUS EVENT CODE: A-4-4-R10-R13-R104 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CHANGE OF NAME REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20250708

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 16TH ANNIV.) - SMALL

Year of fee payment: 16

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20251231

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20251231