AU2008284116B2 - Use of interleukin-22 in the treatment of fatty liver disease - Google Patents

Use of interleukin-22 in the treatment of fatty liver disease Download PDF

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Publication number
AU2008284116B2
AU2008284116B2 AU2008284116A AU2008284116A AU2008284116B2 AU 2008284116 B2 AU2008284116 B2 AU 2008284116B2 AU 2008284116 A AU2008284116 A AU 2008284116A AU 2008284116 A AU2008284116 A AU 2008284116A AU 2008284116 B2 AU2008284116 B2 AU 2008284116B2
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fatty liver
cells
liver
liver disease
treatment
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AU2008284116A1 (en
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Yu Liang Huang
Zhi Hua Huang
Qi Sun
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Evive Biotechnology Shanghai Ltd
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Evive Biotechnology Shanghai Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008284116A 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease Active AU2008284116B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNCN200710044592.7 2007-08-06
CN2007100445927A CN101361968B (zh) 2007-08-06 2007-08-06 白介素-22在治疗脂肪肝中的应用
PCT/US2008/071859 WO2009020844A1 (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Publications (2)

Publication Number Publication Date
AU2008284116A1 AU2008284116A1 (en) 2009-02-12
AU2008284116B2 true AU2008284116B2 (en) 2014-01-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008284116A Active AU2008284116B2 (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Country Status (7)

Country Link
US (3) US20110262385A1 (enExample)
EP (1) EP2185202B1 (enExample)
JP (1) JP5546453B2 (enExample)
CN (1) CN101361968B (enExample)
AU (1) AU2008284116B2 (enExample)
CA (1) CA2695734C (enExample)
WO (1) WO2009020844A1 (enExample)

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CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
EP2616045B1 (en) 2010-09-15 2017-10-25 Randall J. Mrsny Systems and methods of delivery of bioactive agents using bacterial toxin-derived transport sequences
US11246915B2 (en) 2010-09-15 2022-02-15 Applied Molecular Transport Inc. Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
WO2013013613A1 (zh) 2011-07-25 2013-01-31 健能隆医药技术（上海）有限公司 G-csf二聚体在制备治疗神经退行性疾病药物中的应用
CN103182072B (zh) 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
RS57393B1 (sr) 2013-03-15 2018-09-28 Hoffmann La Roche Il-22 polipeptiidi i il-22 fuzioni proteini i metode za njihovu upotrebu
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
SI3139965T1 (sl) 2014-05-07 2022-01-31 Applied Molecular Transport Inc. Fuzijske molekule, izpeljane iz toksina cholix, za peroralno dostavljanje biološko aktivnega tovora
EP3149049B1 (en) * 2014-05-27 2022-10-26 The University Of Queensland Il-22 for use in treating metabolic disorders
WO2016144862A1 (en) 2015-03-09 2016-09-15 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
WO2017181143A1 (en) 2016-04-15 2017-10-19 Generon (Shanghai) Corporation, Ltd. Use of il-22 in treating necrotizing enterocolitis
CN110996951A (zh) 2017-04-03 2020-04-10 科赫罗斯生物科学股份有限公司 治疗进行性核上性麻痹的PPARγ激动剂
IL282986B2 (en) 2018-11-07 2024-01-01 Applied Molecular Transport Inc Colics-derivative carriers for oral administration of heterologous cargo
PL3650037T3 (pl) 2018-11-07 2022-06-06 Applied Molecular Transport Inc. Konstrukty dostarczające do transcytozy i powiązane z nimi sposoby
CA3150859A1 (en) 2019-08-16 2021-02-25 Applied Molecular Transport Inc. Compositions, formulations, and interleukin production and purification
JPWO2022050230A1 (enExample) * 2020-09-03 2022-03-10

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Also Published As

Publication number Publication date
CA2695734A1 (en) 2009-02-12
CN101361968B (zh) 2011-08-03
CN101361968A (zh) 2009-02-11
JP5546453B2 (ja) 2014-07-09
US10786551B2 (en) 2020-09-29
US20180028614A1 (en) 2018-02-01
US20140377222A1 (en) 2014-12-25
US20110262385A1 (en) 2011-10-27
JP2010535786A (ja) 2010-11-25
EP2185202A4 (en) 2013-11-06
EP2185202A1 (en) 2010-05-19
EP2185202B1 (en) 2015-05-06
CA2695734C (en) 2017-02-14
WO2009020844A1 (en) 2009-02-12
AU2008284116A1 (en) 2009-02-12

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