AU2008284116B2 - Use of interleukin-22 in the treatment of fatty liver disease - Google Patents

Use of interleukin-22 in the treatment of fatty liver disease Download PDF

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Publication number
AU2008284116B2
AU2008284116B2 AU2008284116A AU2008284116A AU2008284116B2 AU 2008284116 B2 AU2008284116 B2 AU 2008284116B2 AU 2008284116 A AU2008284116 A AU 2008284116A AU 2008284116 A AU2008284116 A AU 2008284116A AU 2008284116 B2 AU2008284116 B2 AU 2008284116B2
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fatty liver
cells
liver
liver disease
treatment
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AU2008284116A1 (en
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Yu Liang Huang
Zhi Hua Huang
Qi Sun
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Evive Biotechnology Shanghai Ltd
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Evive Biotechnology Shanghai Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008284116A 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease Active AU2008284116B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNCN200710044592.7 2007-08-06
CN2007100445927A CN101361968B (zh) 2007-08-06 2007-08-06 白介素-22在治疗脂肪肝中的应用
PCT/US2008/071859 WO2009020844A1 (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Publications (2)

Publication Number Publication Date
AU2008284116A1 AU2008284116A1 (en) 2009-02-12
AU2008284116B2 true AU2008284116B2 (en) 2014-01-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008284116A Active AU2008284116B2 (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Country Status (7)

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US (3) US20110262385A1 (enExample)
EP (1) EP2185202B1 (enExample)
JP (1) JP5546453B2 (enExample)
CN (1) CN101361968B (enExample)
AU (1) AU2008284116B2 (enExample)
CA (1) CA2695734C (enExample)
WO (1) WO2009020844A1 (enExample)

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CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
US11246915B2 (en) 2010-09-15 2022-02-15 Applied Molecular Transport Inc. Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
RU2593715C2 (ru) 2010-09-15 2016-08-10 Рэндэлл Дж. МРСНИ Системы и способы доставки биоактивных средств с применением транспортных последовательностей, происходящих от бактериального токсина
CA2842969C (en) 2011-07-25 2018-03-27 Generon (Shanghai) Corporation Ltd. Use of g-csf dimer in preparation of medicament for treatment of neurodegenerative diseases
CN103182072B (zh) 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
RS57393B1 (sr) 2013-03-15 2018-09-28 Hoffmann La Roche Il-22 polipeptiidi i il-22 fuzioni proteini i metode za njihovu upotrebu
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
CN117298254A (zh) 2014-05-07 2023-12-29 应用分子转运公司 用于口服递送生物活性货物的cholix毒素衍生的融合分子
EP3149049B1 (en) * 2014-05-27 2022-10-26 The University Of Queensland Il-22 for use in treating metabolic disorders
WO2016144862A1 (en) 2015-03-09 2016-09-15 Intekrin Therapeutics, Inc. Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
CN109328069B (zh) 2016-04-15 2023-09-01 亿一生物医药开发(上海)有限公司 Il-22在治疗坏死性小肠结肠炎中的用途
KR20200036808A (ko) 2017-04-03 2020-04-07 코히러스 바이오사이언시스, 인크. 진행성 핵상 마비 치료를 위한 PPARγ 작용제
ES2911075T3 (es) 2018-11-07 2022-05-17 Applied Molecular Transport Inc Constructos de administración para transcitosis y métodos relacionados
MX2021005382A (es) 2018-11-07 2021-11-12 Applied Molecular Transport Inc Vehiculos derivados de cholix para suministro oral de carga util heterologa.
KR20220066056A (ko) 2019-08-16 2022-05-23 어플라이드 몰레큘라 트랜스포트 인크. 조성물, 제형, 및 인터루킨 제조 및 정제
US12527875B2 (en) 2020-02-19 2026-01-20 Evive Biotechnology (Shanghai) Ltd Methods for treating graft versus host disease
JPWO2022050230A1 (enExample) * 2020-09-03 2022-03-10

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Also Published As

Publication number Publication date
US20180028614A1 (en) 2018-02-01
EP2185202B1 (en) 2015-05-06
WO2009020844A1 (en) 2009-02-12
AU2008284116A1 (en) 2009-02-12
JP2010535786A (ja) 2010-11-25
US20140377222A1 (en) 2014-12-25
JP5546453B2 (ja) 2014-07-09
CN101361968A (zh) 2009-02-11
CA2695734C (en) 2017-02-14
EP2185202A1 (en) 2010-05-19
CA2695734A1 (en) 2009-02-12
CN101361968B (zh) 2011-08-03
US10786551B2 (en) 2020-09-29
EP2185202A4 (en) 2013-11-06
US20110262385A1 (en) 2011-10-27

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