AU2008247488B2 - Amino acid lipids and uses thereof - Google Patents
Amino acid lipids and uses thereof Download PDFInfo
- Publication number
- AU2008247488B2 AU2008247488B2 AU2008247488A AU2008247488A AU2008247488B2 AU 2008247488 B2 AU2008247488 B2 AU 2008247488B2 AU 2008247488 A AU2008247488 A AU 2008247488A AU 2008247488 A AU2008247488 A AU 2008247488A AU 2008247488 B2 AU2008247488 B2 AU 2008247488B2
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- Australia
- Prior art keywords
- compound
- amino acid
- pct
- salt
- mmol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- -1 Amino acid lipids Chemical class 0.000 title abstract description 225
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- 239000013543 active substance Substances 0.000 claims description 61
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- 125000003342 alkenyl group Chemical group 0.000 claims description 47
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- 125000002091 cationic group Chemical group 0.000 claims description 41
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C12N2320/00—Applications; Uses
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