AU2007269070B2 - Bicyclic heteroaryl inhibitors of PDE4 - Google Patents
Bicyclic heteroaryl inhibitors of PDE4 Download PDFInfo
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- AU2007269070B2 AU2007269070B2 AU2007269070A AU2007269070A AU2007269070B2 AU 2007269070 B2 AU2007269070 B2 AU 2007269070B2 AU 2007269070 A AU2007269070 A AU 2007269070A AU 2007269070 A AU2007269070 A AU 2007269070A AU 2007269070 B2 AU2007269070 B2 AU 2007269070B2
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/4704—2-Quinolinones, e.g. carbostyril
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US88682507P | 2007-01-26 | 2007-01-26 | |
| US60/886,825 | 2007-01-26 | ||
| PCT/US2007/072919 WO2008006050A2 (en) | 2006-07-07 | 2007-07-06 | Bicyclic heteroaryl inhibitors of pde4 |
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| AU2007269070A1 AU2007269070A1 (en) | 2008-01-10 |
| AU2007269070B2 true AU2007269070B2 (en) | 2013-03-21 |
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| JP (2) | JP5280357B2 (enExample) |
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| CN (1) | CN104606194A (enExample) |
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| CA (1) | CA2657093A1 (enExample) |
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| MX (1) | MX2009000148A (enExample) |
| WO (3) | WO2008006050A2 (enExample) |
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| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| WO2003078448A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
| DE602004023921D1 (de) | 2003-03-10 | 2009-12-17 | Nycomed Gmbh | Neues verfahren zur herstellung vonroflumilast |
| US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| US8221804B2 (en) * | 2005-02-03 | 2012-07-17 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
| US8663694B2 (en) * | 2005-03-16 | 2014-03-04 | Takeda Gmbh | Taste masked dosage form containing roflumilast |
| US8138205B2 (en) * | 2006-07-07 | 2012-03-20 | Kalypsys, Inc. | Heteroarylalkoxy-substituted quinolone inhibitors of PDE4 |
| CA2657093A1 (en) * | 2006-07-07 | 2008-01-10 | Steven P. Govek | Bicyclic heteroaryl inhibitors of pde4 |
| EP2282735B1 (en) | 2008-04-21 | 2019-01-16 | Signum Biosciences, Inc. | Pp2a modulators for treating alzheimer, parkinson, diabetes |
| CN101353338B (zh) * | 2008-07-10 | 2011-05-04 | 上海交通大学 | 糖胺改性的水溶性香豆素酮衍生物及其制备方法 |
| BR112012007091A2 (pt) * | 2009-10-01 | 2016-04-19 | Alcon Res Ltd | composições de olopatadina e seus usos |
| AR081377A1 (es) | 2010-05-10 | 2012-08-29 | Gilead Sciences Inc | Compuestos de pirazolopiridina bifuncionales |
| NZ603136A (en) | 2010-05-10 | 2014-11-28 | Gilead Sciences Inc | Bifunctional quinoline derivatives |
| US20130116279A1 (en) * | 2011-11-07 | 2013-05-09 | Kalypsys, Inc. | Bicyclic heteroaryl inhibitors of pde4 |
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- 2007-07-06 CN CN201410768897.2A patent/CN104606194A/zh active Pending
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Also Published As
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|---|---|
| KR20150004441A (ko) | 2015-01-12 |
| EP2037924A2 (en) | 2009-03-25 |
| JP2013177421A (ja) | 2013-09-09 |
| US8258154B2 (en) | 2012-09-04 |
| WO2008006052A3 (en) | 2008-11-20 |
| CO6190532A2 (es) | 2010-08-19 |
| WO2008006051A3 (en) | 2008-06-26 |
| JP5705269B2 (ja) | 2015-04-22 |
| US7745646B2 (en) | 2010-06-29 |
| MX2009000148A (es) | 2009-10-26 |
| BRPI0713253A2 (pt) | 2012-10-30 |
| AU2007269070A1 (en) | 2008-01-10 |
| WO2008006050A2 (en) | 2008-01-10 |
| JP5280357B2 (ja) | 2013-09-04 |
| CN104606194A (zh) | 2015-05-13 |
| WO2008006052A2 (en) | 2008-01-10 |
| US20100022586A1 (en) | 2010-01-28 |
| US20130178498A1 (en) | 2013-07-11 |
| CA2657093A1 (en) | 2008-01-10 |
| US20080027099A1 (en) | 2008-01-31 |
| JP2009542815A (ja) | 2009-12-03 |
| KR20090109527A (ko) | 2009-10-20 |
| US9078887B2 (en) | 2015-07-14 |
| US20090291950A1 (en) | 2009-11-26 |
| US8080563B2 (en) | 2011-12-20 |
| WO2008006050A3 (en) | 2008-06-26 |
| WO2008006051A2 (en) | 2008-01-10 |
| US20080027112A1 (en) | 2008-01-31 |
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