AU2007215334B2 - Polynucleotides and polypeptide sequences involved in the process of bone remodeling - Google Patents

Polynucleotides and polypeptide sequences involved in the process of bone remodeling Download PDF

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Publication number
AU2007215334B2
AU2007215334B2 AU2007215334A AU2007215334A AU2007215334B2 AU 2007215334 B2 AU2007215334 B2 AU 2007215334B2 AU 2007215334 A AU2007215334 A AU 2007215334A AU 2007215334 A AU2007215334 A AU 2007215334A AU 2007215334 B2 AU2007215334 B2 AU 2007215334B2
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Prior art keywords
seq
polynucleotide
polypeptide
sequence
bone
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AU2007215334A1 (en
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Mario Filion
Roy Rabindranauth Sooknanan
Gilles Bernard Tremblay
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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Priority to AU2014200123A priority Critical patent/AU2014200123B2/en
Assigned to DAIICHI SANKYO COMPANY, LIMITED reassignment DAIICHI SANKYO COMPANY, LIMITED Request for Assignment Assignors: ALETHIA BIOTHERAPEUTICS INC.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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    • C07K2317/00—Immunoglobulins specific features
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12Q2600/00—Oligonucleotides characterized by their use
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  • Proteomics, Peptides & Aminoacids (AREA)
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AU2007215334A 2006-02-13 2007-02-13 Polynucleotides and polypeptide sequences involved in the process of bone remodeling Ceased AU2007215334B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014200123A AU2014200123B2 (en) 2006-02-13 2014-01-09 Polynucleotides and polypeptide sequences involved in the process of bone remodeling

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77258506P 2006-02-13 2006-02-13
US60/772,585 2006-02-13
US81685806P 2006-06-28 2006-06-28
US60/816,858 2006-06-28
PCT/CA2007/000210 WO2007093042A1 (en) 2006-02-13 2007-02-13 Polynucleotides and polypeptide sequences involved in the process of bone remodeling

Related Child Applications (1)

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AU2014200123A Division AU2014200123B2 (en) 2006-02-13 2014-01-09 Polynucleotides and polypeptide sequences involved in the process of bone remodeling

Publications (2)

Publication Number Publication Date
AU2007215334A1 AU2007215334A1 (en) 2007-08-23
AU2007215334B2 true AU2007215334B2 (en) 2013-11-21

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AU2007215334A Ceased AU2007215334B2 (en) 2006-02-13 2007-02-13 Polynucleotides and polypeptide sequences involved in the process of bone remodeling

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US (7) US7989160B2 (enExample)
EP (2) EP1994155B2 (enExample)
JP (5) JP5173838B2 (enExample)
AU (1) AU2007215334B2 (enExample)
CA (2) CA2638823A1 (enExample)
DK (1) DK1994155T4 (enExample)
ES (1) ES2397441T5 (enExample)
WO (1) WO2007093042A1 (enExample)

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DK1994155T4 (da) 2006-02-13 2022-07-25 Daiichi Sankyo Co Ltd Polynukleotid- og polypeptidsekvenser involveret i fremgangsmåden med knogleremodellering
US8168181B2 (en) * 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
SG10201605897RA (en) * 2007-10-11 2016-09-29 Daiichi Sankyo Co Ltd ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN Siglec-15
KR20100099260A (ko) * 2007-12-12 2010-09-10 디에스엠 아이피 어셋츠 비.브이. 염증성 장애의 치료, 병용-치료 또는 예방을 위한 하이드록시티로솔 및 콘드로이틴을 포함하는 조성물
JP5574600B2 (ja) * 2007-12-17 2014-08-20 日本製薬工業株式会社 吸収性骨疾患の予防・治療剤
JP2012509888A (ja) * 2008-11-21 2012-04-26 ザ ジェイ． デヴィッド グラッドストーン インスティテューツ ＡｐｏＥ関連障害の治療におけるＡｐｏＥ切断活性の阻害
MX2011007342A (es) * 2009-04-09 2011-07-21 Daiichi Sankyo Co Ltd Anticuerpo anti-lectina similar a inmunoglobulina de union a acido sialico-15.
BR112013008255A2 (pt) 2010-10-05 2018-09-25 Daiichi Sankyo Co Ltd anticorpo isolado ou um fragmento funcional do mesmo, uso de um anticorpo isolado ou de um fragmento funcional do mesmo, composição farmacêutica, polinucleotídeo, vetor, célula transformada, e, método para produzir anticorpo
KR20140138215A (ko) 2012-03-30 2014-12-03 다이이찌 산쿄 가부시키가이샤 신규 항 Ｓｉｇｌｅｃ-15 항체
NZ631509A (en) 2012-03-30 2016-09-30 Daiichi Sankyo Co Ltd Cdr-modified anti-siglec-15 antibody
US9493562B2 (en) 2012-07-19 2016-11-15 Alethia Biotherapeutics Inc. Anti-Siglec-15 antibodies
JP2014230493A (ja) * 2013-05-28 2014-12-11 三菱レイヨン株式会社 間葉系幹細胞からの分化状態を識別する遺伝子群及び分化状態の評価方法
EP3515478B1 (en) 2016-09-21 2024-02-28 Nextcure, Inc. Antibodies for siglec-15 and methods of use thereof
CN110913905A (zh) 2017-06-30 2020-03-24 国立大学法人北海道大学 不产生生长障碍的小儿骨质疏松症治疗药
KR102840561B1 (ko) * 2021-06-03 2025-08-01 주식회사 메드팩토 Tm4sf19 억제제 및 이의 용도
CN114560924B (zh) * 2022-02-21 2023-06-20 华南理工大学 一种促进成骨细胞分化的含硒特立帕肽和融合多肽及其应用

Citations (2)

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