AU2006300207C1 - Agent for applying to mucosa and method for production thereof - Google Patents

Agent for applying to mucosa and method for production thereof Download PDF

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Publication number
AU2006300207C1
AU2006300207C1 AU2006300207A AU2006300207A AU2006300207C1 AU 2006300207 C1 AU2006300207 C1 AU 2006300207C1 AU 2006300207 A AU2006300207 A AU 2006300207A AU 2006300207 A AU2006300207 A AU 2006300207A AU 2006300207 C1 AU2006300207 C1 AU 2006300207C1
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AU
Australia
Prior art keywords
mucosa
group
administration
agent
gag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006300207A
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English (en)
Other versions
AU2006300207A1 (en
AU2006300207B2 (en
Inventor
Kenji Miyamoto
Yuuji Shimojima
Katsuya Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Publication of AU2006300207A1 publication Critical patent/AU2006300207A1/en
Publication of AU2006300207B2 publication Critical patent/AU2006300207B2/en
Priority to AU2012201314A priority Critical patent/AU2012201314B2/en
Application granted granted Critical
Publication of AU2006300207C1 publication Critical patent/AU2006300207C1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043Fluorescein, used in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/005Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AU2006300207A 2005-10-12 2006-10-12 Agent for applying to mucosa and method for production thereof Ceased AU2006300207C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012201314A AU2012201314B2 (en) 2005-10-12 2012-02-29 Agent for applying to mucosa and method for production thereof

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005-297170 2005-10-12
JP2005297170 2005-10-12
JP2006-160478 2006-06-09
JP2006160478 2006-06-09
PCT/JP2006/320801 WO2007043702A1 (en) 2005-10-12 2006-10-12 Agent for applying to mucosa and method for production thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012201314A Division AU2012201314B2 (en) 2005-10-12 2012-02-29 Agent for applying to mucosa and method for production thereof

Publications (3)

Publication Number Publication Date
AU2006300207A1 AU2006300207A1 (en) 2007-04-19
AU2006300207B2 AU2006300207B2 (en) 2011-12-01
AU2006300207C1 true AU2006300207C1 (en) 2012-05-24

Family

ID=37942916

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006300207A Ceased AU2006300207C1 (en) 2005-10-12 2006-10-12 Agent for applying to mucosa and method for production thereof

Country Status (9)

Country Link
US (4) US20080306022A1 (https=)
EP (1) EP1942912B1 (https=)
JP (3) JP4387445B2 (https=)
KR (4) KR101554834B1 (https=)
CN (3) CN103120701B (https=)
AU (1) AU2006300207C1 (https=)
CA (1) CA2625532C (https=)
ES (1) ES2616295T3 (https=)
WO (1) WO2007043702A1 (https=)

Families Citing this family (22)

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GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CA2625532C (en) * 2005-10-12 2013-10-01 Seikagaku Corporation Agent for applying to mucosa containing a hydrophobic group binding type glycosaminoglycan
AU2007328871B2 (en) 2006-12-06 2013-11-21 Seikagaku Corporation Pharmaceutical agent having long-lasting effect of treating arthritic disorders
JP2009046454A (ja) * 2007-08-22 2009-03-05 Shiseido Co Ltd 口腔内用組成物
ITMI20072237A1 (it) * 2007-11-27 2009-05-28 Sigea Srl Esteri misti butirrico-formico di polisaccaridi acidi, loro preparazione ed uso come dermocosmetici
CA2719666C (en) 2008-04-04 2016-08-16 Glenn Prestwich Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
WO2010053140A1 (ja) * 2008-11-05 2010-05-14 国立大学法人 東京医科歯科大学 ヒアルロン酸誘導体、およびその医薬組成物
FR2958646B1 (fr) 2010-04-07 2012-05-18 Adocia Polysaccharides comportant des groupes fonctionnels carboxyles substitues par un derive d'acide hydrophobe.
CA2703532C (en) * 2010-05-10 2018-05-01 Eva Turley Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications
WO2012129461A1 (en) 2011-03-23 2012-09-27 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
US9067299B2 (en) 2012-04-25 2015-06-30 Applied Materials, Inc. Printed chemical mechanical polishing pad
CA2972212C (en) * 2014-12-26 2024-10-29 Seikagaku Corporation AGENT AND IMPROVEMENT OF SUBJECTIVE OCULAR SYMPTOMS AND ASSOCIATED METHOD
CN104940221A (zh) * 2015-05-13 2015-09-30 北京大清生物技术有限公司 一种用于膀胱和尿道上皮损伤修复的组合物
EP3305304A4 (en) * 2015-05-29 2019-01-23 Seikagaku Corporation COMPOSITION WITH GLUCOSAMINATE SCANDERIVATE AND CHEMOKIN RECEPTOR ACTIVITY CONTROLLER
JP6757731B2 (ja) * 2015-08-20 2020-09-23 生化学工業株式会社 眼用デバイス適用剤
US10525159B2 (en) 2016-05-26 2020-01-07 Ophtecs Corporation Liquid preparation for contact lenses comprising hydrolyzed hyaluronic acid derivative and cationic bactericide
US11337994B2 (en) 2016-09-15 2022-05-24 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
US20190240251A1 (en) * 2016-10-14 2019-08-08 i.com medical GmbH Method for establishing, restoring, and preserving homeostasis of the ocular surface
SG10202107829YA (en) 2017-03-22 2021-08-30 Genentech Inc Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
RU2652581C1 (ru) * 2017-07-03 2018-04-26 федеральное государственное бюджетное образовательное учреждение высшего образования "Приволжский исследовательский медицинский университет" Министерства здравоохранения Российской Федерации Способ лечения роговично-конъюнктивального ксероза
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
EP4039279A4 (en) 2019-10-03 2023-11-01 Seikagaku Corporation TRANSMUCOSAL MEDICINAL ACTIVE DELIVERY SYSTEM FOR THE BLADDER SUBMUCOSA

Citations (9)

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JPH01238530A (ja) * 1988-03-17 1989-09-22 Seikagaku Kogyo Co Ltd 角膜上皮層障害症治療剤
JPH0673102A (ja) * 1992-02-05 1994-03-15 Seikagaku Kogyo Co Ltd 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
JPH08143604A (ja) * 1994-11-17 1996-06-04 Seikagaku Kogyo Co Ltd 光架橋性ヒアルロン酸誘導体とその架橋体およびそれらの製造方法
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
WO1998029125A1 (fr) * 1996-12-27 1998-07-09 Seikagaku Corporation Remedes contre des troubles de la vessie
WO2000001733A1 (en) * 1998-07-06 2000-01-13 Fidia Advanced Biopolymers S.R.L. Amides of hyaluronic acid and the derivatives thereof and a process for their preparation
WO2000056344A1 (fr) * 1999-03-24 2000-09-28 Seikagaku Corporation Salive artificielle
JP2002356447A (ja) * 2001-03-30 2002-12-13 Chisso Corp 婦人科疾患治療剤
US6602859B2 (en) * 2000-12-19 2003-08-05 Seikagaku Corporation Photocurable hyaluronic acid derivative and process for producing the same, and photocured crosslinked-hyaluronic acid derivative and medical material using the same

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DE4203529A1 (de) * 1992-02-07 1993-08-12 Wolff Walsrode Ag Wasserloesliche sulfoalkylhydroxyalkylderivate der cellulose und deren verwendung in gips- und zementhaltigen massen
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JP4006039B2 (ja) * 1995-09-13 2007-11-14 生化学工業株式会社 光架橋ヒアルロン酸コンタクトレンズ
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JP3439481B2 (ja) * 1995-11-15 2003-08-25 生化学工業株式会社 光架橋ヒアルロン酸ゲルおよびその製造法
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JPH1171282A (ja) 1997-09-01 1999-03-16 Senju Pharmaceut Co Ltd 点眼用水性製剤
JP3014357B2 (ja) 1998-01-26 2000-02-28 生化学工業株式会社 角膜上皮層伸展促進剤
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JP2002037746A (ja) 2000-07-24 2002-02-06 Fuji Yakuhin:Kk キノロンカルボン酸系抗菌剤を含有する液剤
JP4172176B2 (ja) 2000-12-19 2008-10-29 生化学工業株式会社 光反応性ヒアルロン酸およびその製造方法ならびに光架橋ヒアルロン酸および医用材料
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WO2006030965A1 (en) * 2004-09-15 2006-03-23 Seikagaku Corporation Photoreactive polysaccharide, photocrosslinked polysaccharide products, the method of making them and medical materials therefrom
CA2625532C (en) * 2005-10-12 2013-10-01 Seikagaku Corporation Agent for applying to mucosa containing a hydrophobic group binding type glycosaminoglycan
JP7023317B2 (ja) * 2020-05-12 2022-02-21 沖電気工業株式会社 光波長フィルタ及び波長分離光回路

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01238530A (ja) * 1988-03-17 1989-09-22 Seikagaku Kogyo Co Ltd 角膜上皮層障害症治療剤
US5733892A (en) * 1990-07-24 1998-03-31 Seikagaku Corporation Metastasis inhibitor composition comprising a phospholipid-linked glycosaminoglycan and method for inhibiting metastasis employing the same
JPH0673102A (ja) * 1992-02-05 1994-03-15 Seikagaku Kogyo Co Ltd 光反応性グリコサミノグリカン、架橋グリコサミノグリカン及びそれらの製造方法
JPH08143604A (ja) * 1994-11-17 1996-06-04 Seikagaku Kogyo Co Ltd 光架橋性ヒアルロン酸誘導体とその架橋体およびそれらの製造方法
WO1998029125A1 (fr) * 1996-12-27 1998-07-09 Seikagaku Corporation Remedes contre des troubles de la vessie
WO2000001733A1 (en) * 1998-07-06 2000-01-13 Fidia Advanced Biopolymers S.R.L. Amides of hyaluronic acid and the derivatives thereof and a process for their preparation
WO2000056344A1 (fr) * 1999-03-24 2000-09-28 Seikagaku Corporation Salive artificielle
US6602859B2 (en) * 2000-12-19 2003-08-05 Seikagaku Corporation Photocurable hyaluronic acid derivative and process for producing the same, and photocured crosslinked-hyaluronic acid derivative and medical material using the same
JP2002356447A (ja) * 2001-03-30 2002-12-13 Chisso Corp 婦人科疾患治療剤

Also Published As

Publication number Publication date
KR20140054368A (ko) 2014-05-08
EP1942912A1 (en) 2008-07-16
HK1184700A1 (en) 2014-01-30
JP2012211171A (ja) 2012-11-01
WO2007043702A9 (en) 2007-06-07
KR20080056012A (ko) 2008-06-19
KR101411067B1 (ko) 2014-06-27
JP2009298798A (ja) 2009-12-24
HK1184701A1 (en) 2014-01-30
ES2616295T3 (es) 2017-06-12
KR101554834B1 (ko) 2015-09-21
US20150196574A1 (en) 2015-07-16
JP4387445B2 (ja) 2009-12-16
EP1942912B1 (en) 2016-12-14
CN103120701B (zh) 2014-11-05
US8969319B2 (en) 2015-03-03
KR101428153B1 (ko) 2014-08-07
AU2006300207A1 (en) 2007-04-19
JP5094799B2 (ja) 2012-12-12
EP1942912A4 (en) 2010-10-06
JP2009511423A (ja) 2009-03-19
CA2625532A1 (en) 2007-04-19
CN101287473B (zh) 2013-01-02
US20110207695A1 (en) 2011-08-25
CN103120702B (zh) 2014-11-05
WO2007043702A1 (en) 2007-04-19
CA2625532C (en) 2013-10-01
CN101287473A (zh) 2008-10-15
AU2006300207B2 (en) 2011-12-01
CN103120701A (zh) 2013-05-29
US20080306022A1 (en) 2008-12-11
KR20130109259A (ko) 2013-10-07
US20180289730A1 (en) 2018-10-11
KR20110120983A (ko) 2011-11-04
CN103120702A (zh) 2013-05-29

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