AU2006298767B2 - Interleukin-1 conjugates and uses thereof - Google Patents
Interleukin-1 conjugates and uses thereof Download PDFInfo
- Publication number
- AU2006298767B2 AU2006298767B2 AU2006298767A AU2006298767A AU2006298767B2 AU 2006298767 B2 AU2006298767 B2 AU 2006298767B2 AU 2006298767 A AU2006298767 A AU 2006298767A AU 2006298767 A AU2006298767 A AU 2006298767A AU 2006298767 B2 AU2006298767 B2 AU 2006298767B2
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- AU
- Australia
- Prior art keywords
- seq
- composition
- protein
- vlp
- molecule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P17/04—Antipruritics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
- A—HUMAN NECESSITIES
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
- C12N2795/18111—Leviviridae
- C12N2795/18123—Virus like particles [VLP]
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013202547A AU2013202547A1 (en) | 2005-09-28 | 2013-04-04 | Interleukin-1 conjugates and uses thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72110605P | 2005-09-28 | 2005-09-28 | |
| US60/721,106 | 2005-09-28 | ||
| PCT/EP2006/066866 WO2007039552A1 (en) | 2005-09-28 | 2006-09-28 | Interleukin-1 conjugates and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013202547A Division AU2013202547A1 (en) | 2005-09-28 | 2013-04-04 | Interleukin-1 conjugates and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2006298767A1 AU2006298767A1 (en) | 2007-04-12 |
| AU2006298767B2 true AU2006298767B2 (en) | 2013-01-10 |
Family
ID=37497973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006298767A Ceased AU2006298767B2 (en) | 2005-09-28 | 2006-09-28 | Interleukin-1 conjugates and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20110027220A1 (enExample) |
| EP (2) | EP2431468A1 (enExample) |
| JP (1) | JP5312028B2 (enExample) |
| KR (1) | KR20080047564A (enExample) |
| CN (2) | CN101267834B (enExample) |
| AU (1) | AU2006298767B2 (enExample) |
| BR (1) | BRPI0616446A2 (enExample) |
| CA (1) | CA2623287A1 (enExample) |
| IL (1) | IL189245A0 (enExample) |
| NZ (1) | NZ566971A (enExample) |
| RU (1) | RU2441067C2 (enExample) |
| WO (1) | WO2007039552A1 (enExample) |
| ZA (1) | ZA200802225B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1450856B1 (en) | 2001-09-14 | 2009-11-11 | Cytos Biotechnology AG | Packaging of immunostimulatory cpg into virus-like particles: method of preparation and use |
| DK1915620T3 (da) | 2005-08-02 | 2010-10-04 | Xbiotech Inc | Diagnose, behandling og prævention af vaskulære sygdomme ved hjælp af IL-1alpha-autoantistoffer |
| EP2021033B1 (en) | 2006-05-15 | 2012-03-28 | XBiotech, Inc | Il-1-alpha for use in a method of treatment of atherosclerotic plaques. |
| US20110008282A1 (en) * | 2006-05-15 | 2011-01-13 | Xbiotech, Inc. | IL-1alpha immunization induces autoantibodies protective against atherosclerosis |
| SI2032592T1 (sl) | 2006-06-12 | 2013-10-30 | Cytos Biotechnology Ag | Postopki za pakiranje oligonukleotidov v virusu-podobne delce RNA bakteriofagov |
| WO2008071774A1 (en) * | 2006-12-14 | 2008-06-19 | Cytos Biotechnology Ag | Purification process for coat protein of rna bacteriophages |
| KR20100084623A (ko) * | 2007-09-25 | 2010-07-27 | 인터벳 인터내셔널 비.브이. | 골관절염 치료용 백신 |
| NZ587670A (en) * | 2008-03-05 | 2012-11-30 | Cytos Biotechnology Ag | Use of interleukin-1 conjugates in the treatment of diabetes |
| HUE029003T2 (en) | 2008-05-30 | 2017-01-30 | Xbiotech Inc | IL-1 alpha antibodies |
| JP5976319B2 (ja) | 2008-09-12 | 2016-08-23 | エックスバイオテク, インコーポレイテッドXbiotech, Inc. | 病原性単球の標的化 |
| PL222496B1 (pl) * | 2009-04-10 | 2016-08-31 | Inst Biochemii I Biofizyki Pan | Wektorowa cząsteczka wirusopodobna, sposób jej wytwarzania oraz kompozycja farmaceutyczna zawierająca wektorową cząsteczkę wirusopodobną |
| US8993715B2 (en) * | 2009-07-06 | 2015-03-31 | Canon Kabushiki Kaisha | Labeled protein and method for obtaining the same |
| CN102497885A (zh) * | 2009-09-10 | 2012-06-13 | 赛托斯生物技术公司 | 白介素-1β突变蛋白偶联物在糖尿病治疗中的用途 |
| CN102946904A (zh) | 2010-06-18 | 2013-02-27 | 埃克斯生物科技公司 | 关节炎治疗 |
| PH12013500316A1 (en) | 2010-08-23 | 2016-09-02 | Janssen Biotech Inc | Treatment for neoplastic diseases |
| US9724409B2 (en) | 2011-04-01 | 2017-08-08 | Xbiotech, Inc. | Treatment of inflammatory skin disease |
| PT2750709T (pt) | 2011-09-23 | 2018-11-22 | Xbiotech Inc | Tratamento da caquexia |
| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| US9545441B2 (en) | 2012-09-18 | 2017-01-17 | Xbiotech, Inc. | Treatment of diabetes |
| GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
| US11168306B2 (en) | 2014-02-25 | 2021-11-09 | The Regents Of The University Of California | Phage wrapping |
| AU2016207099C1 (en) * | 2015-01-15 | 2021-02-04 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| RU2761555C2 (ru) * | 2015-10-22 | 2021-12-09 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
| KR102908806B1 (ko) | 2015-10-22 | 2026-01-07 | 주노 테라퓨틱스 게엠베하 | 세포의 배양 방법 및 이를 위한 키트와 장치 |
| WO2017071713A1 (en) | 2015-10-30 | 2017-05-04 | University Of Copenhagen | Virus like particle with efficient epitope display |
| JP7145162B2 (ja) | 2017-02-16 | 2022-09-30 | ヤンセン バイオテク,インコーポレイテッド | 化膿性汗腺炎の処置 |
| AU2018260380B2 (en) | 2017-04-27 | 2025-02-13 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| WO2019160866A2 (en) | 2018-02-13 | 2019-08-22 | Checkmate Pharmaceuticals, Inc. | Compositions and methods for tumor immunotherapy |
| BR112020020479A2 (pt) | 2018-04-09 | 2021-01-12 | Checkmate Pharmaceuticals | Empacotamento de oligonucleotídeos em partículas similares a vírus |
| BR112021002390A2 (pt) | 2018-08-09 | 2021-05-11 | Juno Therapeutics Inc | processos para gerar células modificadas e suas composições |
| WO2020089343A1 (en) | 2018-10-31 | 2020-05-07 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
| EP3845556A1 (fr) * | 2019-12-31 | 2021-07-07 | Peptinov SAS | Conjugue immunogene destine a induire une reponse immunitaire dirigee contre l interleukine-6 |
| BR112022022089A2 (pt) * | 2020-05-22 | 2022-12-13 | R Pharm Overseas Inc | Composição de proteína heterodimérica, composição terapêutica que compreende a mesma e uso da dita composição para tratar uma doença associada à modulação de il-1ss |
| CA3095740A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin alpha (il-1a) |
| CA3095679A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleuken 1 alpha (il-1a) |
| CA3095676A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| CA3095675A1 (en) | 2020-10-07 | 2022-04-07 | Xbiotech Inc. | True human antibody specific for interleukin 1 alpha (il-1a) |
| JP2024527571A (ja) * | 2021-07-08 | 2024-07-25 | オリオンズ バイオサイエンス インコーポレイテッド | インターロイキン-1アルファキメラタンパク質 |
| WO2025186318A2 (en) | 2024-03-06 | 2025-09-12 | Elanco Us Inc. | Veterinary compositions of modified virus-like particles of cmv and feline il-1beta mutein antigens |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004007538A2 (en) * | 2002-07-17 | 2004-01-22 | Cytos Biotechnology Ag | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
| ATE165114T1 (de) | 1989-02-27 | 1998-05-15 | New England Medical Center Inc | Il-1, dessen biologische aktivität inhibiert ist |
| EP0563091A1 (en) | 1990-12-20 | 1993-10-06 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccines based on hepatitis b surface antigen |
| GB9101550D0 (en) | 1991-01-24 | 1991-03-06 | Mastico Robert A | Antigen-presenting chimaeric protein |
| FR2677654B1 (fr) | 1991-06-17 | 1995-11-17 | Pasteur Merieux Serums Vacc | Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv. |
| GB9114003D0 (en) | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
| AU700819B2 (en) * | 1994-10-07 | 1999-01-14 | Chugai Seiyaku Kabushiki Kaisha | Rheumatoid arthritis remedy containing IL-6 antagonist as effective component |
| CN1185811A (zh) | 1995-03-31 | 1998-06-24 | H·沃尔夫 | 依赖于逆转录病毒样颗粒的抗原呈递系统 |
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2006
- 2006-09-28 BR BRPI0616446-3A patent/BRPI0616446A2/pt not_active IP Right Cessation
- 2006-09-28 NZ NZ566971A patent/NZ566971A/en not_active IP Right Cessation
- 2006-09-28 US US11/992,731 patent/US20110027220A1/en not_active Abandoned
- 2006-09-28 EP EP11175319A patent/EP2431468A1/en not_active Withdrawn
- 2006-09-28 JP JP2008532788A patent/JP5312028B2/ja not_active Expired - Fee Related
- 2006-09-28 AU AU2006298767A patent/AU2006298767B2/en not_active Ceased
- 2006-09-28 RU RU2008116323/10A patent/RU2441067C2/ru not_active IP Right Cessation
- 2006-09-28 CN CN2006800343698A patent/CN101267834B/zh not_active Expired - Fee Related
- 2006-09-28 KR KR1020087006840A patent/KR20080047564A/ko not_active Withdrawn
- 2006-09-28 CA CA002623287A patent/CA2623287A1/en not_active Abandoned
- 2006-09-28 CN CN2013101441929A patent/CN103230590A/zh active Pending
- 2006-09-28 EP EP06793894A patent/EP1931383A1/en not_active Withdrawn
- 2006-09-28 ZA ZA200802225A patent/ZA200802225B/xx unknown
- 2006-09-28 WO PCT/EP2006/066866 patent/WO2007039552A1/en not_active Ceased
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2007
- 2007-03-29 US US12/443,344 patent/US8449874B2/en not_active Expired - Fee Related
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2008
- 2008-02-04 IL IL189245A patent/IL189245A0/en unknown
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- 2012-08-01 US US13/564,576 patent/US20130230484A1/en not_active Abandoned
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| WO2004007538A2 (en) * | 2002-07-17 | 2004-01-22 | Cytos Biotechnology Ag | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2007039552A1 (en) | 2007-04-12 |
| US20130230484A1 (en) | 2013-09-05 |
| AU2006298767A1 (en) | 2007-04-12 |
| CN101267834B (zh) | 2013-06-05 |
| IL189245A0 (en) | 2008-08-07 |
| CN101267834A (zh) | 2008-09-17 |
| EP1931383A1 (en) | 2008-06-18 |
| CA2623287A1 (en) | 2007-04-12 |
| RU2441067C2 (ru) | 2012-01-27 |
| US8449874B2 (en) | 2013-05-28 |
| JP5312028B2 (ja) | 2013-10-09 |
| KR20080047564A (ko) | 2008-05-29 |
| CN103230590A (zh) | 2013-08-07 |
| ZA200802225B (en) | 2009-10-28 |
| NZ566971A (en) | 2011-06-30 |
| RU2008116323A (ru) | 2009-11-10 |
| US20110091411A1 (en) | 2011-04-21 |
| US20110027220A1 (en) | 2011-02-03 |
| BRPI0616446A2 (pt) | 2011-06-21 |
| JP2009510025A (ja) | 2009-03-12 |
| EP2431468A1 (en) | 2012-03-21 |
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