AU2006291165B2 - Compositions and methods for the diagnosis and therapy of BCL2-associated cancers - Google Patents

Compositions and methods for the diagnosis and therapy of BCL2-associated cancers Download PDF

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Publication number
AU2006291165B2
AU2006291165B2 AU2006291165A AU2006291165A AU2006291165B2 AU 2006291165 B2 AU2006291165 B2 AU 2006291165B2 AU 2006291165 A AU2006291165 A AU 2006291165A AU 2006291165 A AU2006291165 A AU 2006291165A AU 2006291165 B2 AU2006291165 B2 AU 2006291165B2
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mir
cancer
gene product
cell
bcl2
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AU2006291165A1 (en
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George A. Calin
Carlo M. Croce
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Ohio State University Research Foundation
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    • AHUMAN NECESSITIES
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    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
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    • A61P35/02Antineoplastic agents specific for leukemia
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • C12N2310/141MicroRNAs, miRNAs
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    • C12N2310/00Structure or type of the nucleic acid
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    • C12N2320/00Applications; Uses
    • C12N2320/30Special therapeutic applications
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  • Oncology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Dispersion Chemistry (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2006291165A 2005-09-12 2006-09-11 Compositions and methods for the diagnosis and therapy of BCL2-associated cancers Ceased AU2006291165B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71613405P 2005-09-12 2005-09-12
US60/716,134 2005-09-12
PCT/US2006/035100 WO2007033023A2 (en) 2005-09-12 2006-09-11 Compositions and methods for the diagnosis and therapy of bcl2-associated cancers

Publications (2)

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AU2006291165A1 AU2006291165A1 (en) 2007-03-22
AU2006291165B2 true AU2006291165B2 (en) 2013-03-14

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US (3) US8481505B2 (cg-RX-API-DMAC7.html)
EP (2) EP2796554A3 (cg-RX-API-DMAC7.html)
JP (2) JP2009507918A (cg-RX-API-DMAC7.html)
CN (2) CN103028120B (cg-RX-API-DMAC7.html)
AU (1) AU2006291165B2 (cg-RX-API-DMAC7.html)
CA (2) CA2845251A1 (cg-RX-API-DMAC7.html)
ES (1) ES2523989T3 (cg-RX-API-DMAC7.html)
WO (1) WO2007033023A2 (cg-RX-API-DMAC7.html)

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