AU2005259786B2 - Method of detecting mutations in the gene encoding cytochrome P450-2C9 - Google Patents

Method of detecting mutations in the gene encoding cytochrome P450-2C9 Download PDF

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Publication number
AU2005259786B2
AU2005259786B2 AU2005259786A AU2005259786A AU2005259786B2 AU 2005259786 B2 AU2005259786 B2 AU 2005259786B2 AU 2005259786 A AU2005259786 A AU 2005259786A AU 2005259786 A AU2005259786 A AU 2005259786A AU 2005259786 B2 AU2005259786 B2 AU 2005259786B2
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AU
Australia
Prior art keywords
seq
cyp2c9
primers
pcr
primer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005259786A
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English (en)
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AU2005259786A1 (en
Inventor
Frank Merante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Molecular Diagnostics Inc
Original Assignee
Luminex Molecular Diagnostics Inc
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Publication date
Application filed by Luminex Molecular Diagnostics Inc filed Critical Luminex Molecular Diagnostics Inc
Publication of AU2005259786A1 publication Critical patent/AU2005259786A1/en
Assigned to LUMINEX MOLECULAR DIAGNOSTICS, INC. reassignment LUMINEX MOLECULAR DIAGNOSTICS, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: TM BIOSCIENCE PGX, INC.
Application granted granted Critical
Publication of AU2005259786B2 publication Critical patent/AU2005259786B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2005259786A 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome P450-2C9 Ceased AU2005259786B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58361904P 2004-06-30 2004-06-30
US60/583,619 2004-06-30
PCT/CA2005/000998 WO2006002525A1 (en) 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome p450-2c9

Publications (2)

Publication Number Publication Date
AU2005259786A1 AU2005259786A1 (en) 2006-01-12
AU2005259786B2 true AU2005259786B2 (en) 2011-03-10

Family

ID=35782442

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005259786A Ceased AU2005259786B2 (en) 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome P450-2C9

Country Status (6)

Country Link
US (1) US20090099030A1 (enExample)
EP (1) EP1781812A4 (enExample)
JP (1) JP2008504825A (enExample)
AU (1) AU2005259786B2 (enExample)
CA (1) CA2571817A1 (enExample)
WO (1) WO2006002525A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008504826A (ja) * 2004-06-30 2008-02-21 ティーエム バイオサイエンス ピージーエクス インコーポレイティッド チトクロムｐ４５０−２ｄ６をコードする遺伝子における変異を検出する方法
WO2006010266A1 (en) * 2004-07-30 2006-02-02 Tm Bioscience Pgx, Inc. Et Al Method of detecting mutations in the gene encoding cytochrome p450-2c19
GB0506866D0 (en) 2005-04-05 2005-05-11 Rolls Royce Plc A fuel cell arrangement
CN101443448A (zh) * 2006-11-30 2009-05-27 爱科来株式会社 Cyp2c9基因扩增用引物对、含有其的cyp2c9基因扩增用试剂及其用途
EP2215245A2 (en) * 2007-11-02 2010-08-11 Luminex Molecular Diagnostics, Inc. One-step target detection assay
US20110045481A1 (en) * 2008-01-25 2011-02-24 Patrick Gladding Methods and compositions for the assessment of drug response
JP5785942B2 (ja) 2009-06-29 2015-09-30 ルミネックス コーポレーション ヘアピンコンフォメーションを有するキメラプライマーおよびその使用法
TWI600766B (zh) 2012-08-09 2017-10-01 財團法人工業技術研究院 用於偵測一目標核苷酸序列中之一特定區域的一突變及／或多形性的套組

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012757A1 (en) * 1998-08-28 2000-03-09 Sangtec Molecular Diagnostics Ab A method for measuring a patient's ability to metabolise certain drugs
WO2000047766A1 (en) * 1999-02-11 2000-08-17 Astrazeneca Ab Method for detecting variant nucleotides using arms multiplex amplification
WO2004018707A2 (de) * 2002-08-15 2004-03-04 Biotez Berlin-Buch Gmbh Verfahren zum nachweis von einzelnukleotid-polymorphismen (snp) in genen des arzneimittelmetabolismus und testkit zur durchführung des verfahrens

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
JP2001017185A (ja) * 1999-03-19 2001-01-23 Otsuka Pharmaceut Co Ltd 薬物代謝酵素遺伝子多型の簡易検出法
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags
BRPI0206746B8 (pt) * 2001-01-25 2021-07-27 Luminex Molecular Diagnostics Inc composição compreendendo conjuntos de moléculas para uso como rótulos ou complementos de rótulo, kit para classificação e identificação de polinucleotídeos, método de análise de uma amostra biológica e método para determinação da presença de um alvo
EP1456668B1 (en) * 2001-12-05 2007-05-02 Sense Proteomic Limited Protein arrays for allelic variants and uses thereof
JP2006517397A (ja) * 2002-09-16 2006-07-27 センス プロテオミック リミテッド タンパク質アレイ、及びその使用方法
WO2006010266A1 (en) * 2004-07-30 2006-02-02 Tm Bioscience Pgx, Inc. Et Al Method of detecting mutations in the gene encoding cytochrome p450-2c19

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012757A1 (en) * 1998-08-28 2000-03-09 Sangtec Molecular Diagnostics Ab A method for measuring a patient's ability to metabolise certain drugs
WO2000047766A1 (en) * 1999-02-11 2000-08-17 Astrazeneca Ab Method for detecting variant nucleotides using arms multiplex amplification
WO2004018707A2 (de) * 2002-08-15 2004-03-04 Biotez Berlin-Buch Gmbh Verfahren zum nachweis von einzelnukleotid-polymorphismen (snp) in genen des arzneimittelmetabolismus und testkit zur durchführung des verfahrens

Also Published As

Publication number Publication date
US20090099030A1 (en) 2009-04-16
JP2008504825A (ja) 2008-02-21
EP1781812A1 (en) 2007-05-09
AU2005259786A1 (en) 2006-01-12
CA2571817A1 (en) 2006-01-12
WO2006002525A1 (en) 2006-01-12
EP1781812A4 (en) 2008-10-15

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