CA2571817A1 - Method of detecting mutations in the gene encoding cytochrome p450-2c9 - Google Patents

Method of detecting mutations in the gene encoding cytochrome p450-2c9 Download PDF

Info

Publication number
CA2571817A1
CA2571817A1 CA002571817A CA2571817A CA2571817A1 CA 2571817 A1 CA2571817 A1 CA 2571817A1 CA 002571817 A CA002571817 A CA 002571817A CA 2571817 A CA2571817 A CA 2571817A CA 2571817 A1 CA2571817 A1 CA 2571817A1
Authority
CA
Canada
Prior art keywords
seq
cyp2c9
primers
nucleotide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002571817A
Other languages
English (en)
French (fr)
Inventor
Frank Merante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Molecular Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2571817A1 publication Critical patent/CA2571817A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002571817A 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome p450-2c9 Abandoned CA2571817A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58361904P 2004-06-30 2004-06-30
US60/583,619 2004-06-30
PCT/CA2005/000998 WO2006002525A1 (en) 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome p450-2c9

Publications (1)

Publication Number Publication Date
CA2571817A1 true CA2571817A1 (en) 2006-01-12

Family

ID=35782442

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002571817A Abandoned CA2571817A1 (en) 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome p450-2c9

Country Status (6)

Country Link
US (1) US20090099030A1 (enExample)
EP (1) EP1781812A4 (enExample)
JP (1) JP2008504825A (enExample)
AU (1) AU2005259786B2 (enExample)
CA (1) CA2571817A1 (enExample)
WO (1) WO2006002525A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781811B1 (en) * 2004-06-30 2010-06-23 Luminex Molecular Diagnostics, Inc. Method of detecting mutations in the gene encoding cytochrome p450-2d6
US20080248466A1 (en) * 2004-07-30 2008-10-09 Tm Bioscience Pgx Inc. Method Of Detecting Mutations In The Gene Encoding Cytochrome P450-2C19
GB0506866D0 (en) 2005-04-05 2005-05-11 Rolls Royce Plc A fuel cell arrangement
JPWO2008066163A1 (ja) * 2006-11-30 2010-03-11 アークレイ株式会社 Cyp2c9遺伝子増幅用プライマーセット、それを含むcyp2c9遺伝子増幅用試薬およびその用途
CA2704487A1 (en) * 2007-11-02 2009-06-18 Luminex Molecular Diagnostics, Inc. One-step target detection assay
WO2009128730A1 (en) * 2008-01-25 2009-10-22 Patrick Gladding Methods and compositions for the assessment of drug response
CN102686728B (zh) 2009-06-29 2018-09-18 卢米耐克斯公司 具有发夹构象的嵌合引物及其使用方法
TWI600766B (zh) 2012-08-09 2017-10-01 財團法人工業技術研究院 用於偵測一目標核苷酸序列中之一特定區域的一突變及/或多形性的套組

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
JP2002523111A (ja) * 1998-08-28 2002-07-30 サンテック モレキュラー ダイアグノスティックス エービー 特定医薬を代謝することに対する患者の能力を測定する方法
GB9902971D0 (en) * 1999-02-11 1999-03-31 Zeneca Ltd Assay
JP2001017185A (ja) * 1999-03-19 2001-01-23 Otsuka Pharmaceut Co Ltd 薬物代謝酵素遺伝子多型の簡易検出法
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags
EP2327794A3 (en) * 2001-01-25 2011-09-14 TM Bioscience Corporation Polynucleotides for use as tags and tag complements, manufacture and use thereof
JP4781628B2 (ja) * 2001-12-05 2011-09-28 センス プロテオミック リミテッド 対立遺伝子改変体のためのタンパク質アレイおよびその使用
DE10237691B4 (de) * 2002-08-15 2010-01-28 Biotez Berlin-Buch Gmbh Biochemisch-Technologisches Zentrum Verfahren zum Nachweis von Einzelnukleotid-Polymorphismen (SNP) in Genen des Arzneimittelmetabolismus und Testkit zur Durchführung des Verfahrens
WO2004025244A2 (en) * 2002-09-16 2004-03-25 Sense Proteomic Limited Protein arrays and uses thereof
US20080248466A1 (en) * 2004-07-30 2008-10-09 Tm Bioscience Pgx Inc. Method Of Detecting Mutations In The Gene Encoding Cytochrome P450-2C19

Also Published As

Publication number Publication date
AU2005259786B2 (en) 2011-03-10
EP1781812A1 (en) 2007-05-09
US20090099030A1 (en) 2009-04-16
AU2005259786A1 (en) 2006-01-12
WO2006002525A1 (en) 2006-01-12
EP1781812A4 (en) 2008-10-15
JP2008504825A (ja) 2008-02-21

Similar Documents

Publication Publication Date Title
US7879543B2 (en) Method of detecting mutations associated with thrombosis
JP2008200050A (ja) 核酸配列変異を検出するための方法とオリゴヌクレオチド
WO2008076856A2 (en) Reagents and methods for detecting cyp2d6 polymorphisms
Daca-Roszak et al. EurEAs_Gplex—a new SNaPshot assay for continental population discrimination and gender identification
CN101652478A (zh) 免疫相关基因的多态性的检测用探针及其用途
AU2005259786B2 (en) Method of detecting mutations in the gene encoding cytochrome P450-2C9
US20070087350A1 (en) Use of a mutation in the braf gene for the determination of the malignancy of melanoma cells
AU2005266805B2 (en) Method of detecting mutations in the gene encoding Cytochrome P450-2C19
AU2005259787B2 (en) Method of detecting mutations in the gene encoding cytochrome P450-2D6
KR101249635B1 (ko) 양극성 장애 진단용 egr2 유전자 snp, 그를 포함하는 마이크로어레이 및 키트
EP2471949A1 (en) Method for the identification by molecular techniques of genetic variants that encode no D antigen (D-) and altered C antigen (C+W)
US20040209254A1 (en) Diagnostic polymorphisms for the tgf-beta1 promoter
Shammas et al. ThalassoChip, an array mutation and single nucleotide polymorphism detection tool for the diagnosis of β-thalassaemia
CN118562930A (zh) 一种基于液态芯片的snp检测方法
JP2005245273A (ja) アルデヒド脱水素酵素遺伝子多型の簡易検出方法および検出用試薬
JP2001046085A (ja) 血色素症遺伝子を増幅して検出するためのオリゴヌクレオチド
JP2005027519A (ja) ヒトチトクロームp4502a6遺伝子多型の簡易検出方法および検出用試薬
JP2005198525A (ja) グルタチオンs−トランスフェラーゼ遺伝子多型の検出方法および検出用キット
JP2006254738A (ja) 糖尿病疾患感受性遺伝子、及び糖尿病罹患の難易を検出する方法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued