AU2004205684A1 - Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture - Google Patents

Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture Download PDF

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Publication number
AU2004205684A1
AU2004205684A1 AU2004205684A AU2004205684A AU2004205684A1 AU 2004205684 A1 AU2004205684 A1 AU 2004205684A1 AU 2004205684 A AU2004205684 A AU 2004205684A AU 2004205684 A AU2004205684 A AU 2004205684A AU 2004205684 A1 AU2004205684 A1 AU 2004205684A1
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Prior art keywords
amino acid
antibody
variable domain
sequence
antigen binding
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Abandoned
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AU2004205684A
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English (en)
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Laura Simmons
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Genentech Inc
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Genentech Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
AU2004205684A 2003-01-23 2004-01-23 Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture Abandoned AU2004205684A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44248403P 2003-01-23 2003-01-23
US60/442,484 2003-01-23
PCT/US2004/001844 WO2004065417A2 (en) 2003-01-23 2004-01-23 Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture

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AU2004205684A1 true AU2004205684A1 (en) 2004-08-05

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AU2004205684A Abandoned AU2004205684A1 (en) 2003-01-23 2004-01-23 Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture

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US (2) US7575893B2 (US07575893-20090818-C00006.png)
EP (1) EP1585768A2 (US07575893-20090818-C00006.png)
AU (1) AU2004205684A1 (US07575893-20090818-C00006.png)
CA (1) CA2513113A1 (US07575893-20090818-C00006.png)
WO (1) WO2004065417A2 (US07575893-20090818-C00006.png)

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