AU2003294635B8 - Liposomal glucocorticoids - Google Patents

Liposomal glucocorticoids Download PDF

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Publication number
AU2003294635B8
AU2003294635B8 AU2003294635A AU2003294635A AU2003294635B8 AU 2003294635 B8 AU2003294635 B8 AU 2003294635B8 AU 2003294635 A AU2003294635 A AU 2003294635A AU 2003294635 A AU2003294635 A AU 2003294635A AU 2003294635 B8 AU2003294635 B8 AU 2003294635B8
Authority
AU
Australia
Prior art keywords
formulation according
liposomal formulation
liposomes
mole
liposomal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003294635A
Other languages
English (en)
Other versions
AU2003294635A1 (en
AU2003294635A2 (en
AU2003294635B2 (en
Inventor
Rolf Braeuer
Raimund W. Kinne
Steffen Panzer
Una Rauchhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novosom AG
Original Assignee
Novosom AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novosom AG filed Critical Novosom AG
Publication of AU2003294635A1 publication Critical patent/AU2003294635A1/en
Publication of AU2003294635A2 publication Critical patent/AU2003294635A2/en
Application granted granted Critical
Publication of AU2003294635B2 publication Critical patent/AU2003294635B2/en
Publication of AU2003294635B8 publication Critical patent/AU2003294635B8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2003294635A 2002-11-24 2003-11-24 Liposomal glucocorticoids Ceased AU2003294635B8 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10255106.5 2002-11-24
DE10255106A DE10255106A1 (de) 2002-11-24 2002-11-24 Liposomale Glucocorticoide
PCT/DE2003/003893 WO2004047792A2 (de) 2002-11-24 2003-11-24 Liposomale glucocorticoide

Publications (4)

Publication Number Publication Date
AU2003294635A1 AU2003294635A1 (en) 2004-06-18
AU2003294635A2 AU2003294635A2 (en) 2004-06-18
AU2003294635B2 AU2003294635B2 (en) 2009-05-28
AU2003294635B8 true AU2003294635B8 (en) 2009-09-17

Family

ID=32308712

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003294635A Ceased AU2003294635B8 (en) 2002-11-24 2003-11-24 Liposomal glucocorticoids

Country Status (9)

Country Link
US (1) US20060147511A1 (enExample)
EP (1) EP1581185B1 (enExample)
JP (1) JP2006509750A (enExample)
CN (1) CN1731981B (enExample)
AT (1) ATE445389T1 (enExample)
AU (1) AU2003294635B8 (enExample)
CA (1) CA2507316A1 (enExample)
DE (2) DE10255106A1 (enExample)
WO (1) WO2004047792A2 (enExample)

Families Citing this family (28)

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WO2005007169A2 (en) * 2003-07-21 2005-01-27 Vasogen Ireland Limited Liposomes containing phosphate glycerol groups for treating acute inflammatory condition
AU2005281352B2 (en) * 2004-09-09 2011-01-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Liposomal compositions of glucocorticoid and glucocorticoid derivatives
US20080063702A1 (en) * 2004-09-09 2008-03-13 Yechezkel Barenholz Liposomal Formulations Comprising an Amphipathic Weak Base Like Tempamine for Treatment of Neurodegenerative Conditions
KR101254938B1 (ko) 2005-06-10 2013-04-16 포라가세이고오교오가부시끼가이샤 신규 트리테르펜산 유도체 및 이를 포함하는 피부 외용제
JP4980634B2 (ja) * 2006-03-17 2012-07-18 ポーラ化成工業株式会社 肌荒れの予防、改善に好適な皮膚外用剤
WO2008013913A2 (en) * 2006-07-26 2008-01-31 Aciont, Inc. Method and device for minimally invasive site specific ocular drug delivery
CA2664944C (en) * 2006-09-28 2016-06-14 Hadasit Medical Research Services & Development Limited Use of glycerophospholipids for joint lubrication
AU2007306556B2 (en) * 2006-10-13 2014-04-10 Marina Biotech, Inc. Improvements in or relating to amphoteric liposomes
CA2702103A1 (en) * 2007-10-12 2009-04-16 Novosom Ag Improvements in or relating to amphotaric liposomes comprising neutral lipids
EP2127639A1 (en) * 2008-05-26 2009-12-02 Universiteit Utrecht Holding B.V. Corticosteroid containing liposomes for treatment of cardiovascular diseases
PE20120923A1 (es) 2009-03-30 2012-08-27 Eisai Randd Man Co Ltd Composiciones farmaceuticas comprendiendo liposomas que contiene eribulina o una sal del mismo
WO2010113983A1 (ja) * 2009-03-30 2010-10-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 リポソーム組成物の製造方法
CN102366411B (zh) * 2011-09-14 2012-12-19 海南灵康制药有限公司 一种地塞米松棕榈酸酯脂质体注射液
PL2773325T3 (pl) 2011-11-04 2019-03-29 Enceladus Pharmaceuticals B.V. Liposomalne kortykosteroidy w leczeniu chorób zapalnych u istot ludzkich
EP3095440B1 (en) 2015-05-19 2020-01-15 PLS-Design GmbH Antigen-specific immunotherapy using tolerizing liposomes
CN106177959A (zh) * 2016-04-01 2016-12-07 北京大学 抗癌组合物及其制剂和应用
WO2017188350A1 (ja) 2016-04-28 2017-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍の成長を抑制する方法
SG11201809490YA (en) * 2016-04-29 2018-11-29 Enceladus Pharmaceuticals B V Liposomal corticosteroids for topical injection in inflamed lesions or areas
BR112020003767B1 (pt) * 2017-08-22 2023-10-10 Moebius Medical Ltd Composição farmacêutica que compreende lipossomas e uso da dita composição para tratar dor ou irritação em uma articulação
EP3723863A1 (en) 2017-10-18 2020-10-21 Luxembourg Institute of Health (LIH) Hydrogel-embedded oligodeoxynucleotides as tolerogenic adjuvant for subcutaneous immunotherapy
EP3787670A1 (en) 2017-10-18 2021-03-10 Luxembourg Institute of Health (LIH) Induction of allergen-specific tregs prior to oral or sublingual immunotherapy of food allergy
EP3820479B1 (en) 2018-07-09 2026-03-11 Taiwan Liposome Co., Ltd. Methods to reduce complications of intra-articular steroid
ES3075649T3 (en) 2019-07-26 2026-08-06 Eisai R&D Man Co Ltd Pharmaceutical composition for treating tumor
US11083705B2 (en) 2019-07-26 2021-08-10 Eisai R&D Management Co., Ltd. Pharmaceutical composition for treating tumor
CN110974954B (zh) * 2019-12-24 2021-03-16 珠海丽凡达生物技术有限公司 一种用于增强核酸疫苗免疫效果的脂质纳米颗粒及其制备方法
CN111494320A (zh) * 2020-04-24 2020-08-07 上海交通大学医学院附属仁济医院 一种载糖皮质激素的纳米载体及其制备和应用
CA3266614A1 (en) 2023-01-19 2024-07-25 Moebius Medical Ltd. LONG-ACTING LIPOSOMAL COMPOSITION FOR THE TREATMENT OF PAIN IN JOINT DISORDERS
CN117357480B (zh) * 2023-12-08 2024-03-29 北京中科利华医药研究院有限公司 无针经皮注射用组合物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0622072A2 (en) * 1993-04-02 1994-11-02 Wakamoto Pharmaceutical Co., Ltd. Stable aqueous dispersions containing liposomes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
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GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
JPS59222410A (ja) * 1983-06-01 1984-12-14 Terumo Corp 薬物保持リポソ−ム製剤
JPS61197513A (ja) * 1985-02-25 1986-09-01 Ichimaru Fuarukosu Kk 主薬物を内包した安定なリポソ−ムの製剤化法
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US6391336B1 (en) * 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
US6120800A (en) * 1997-09-25 2000-09-19 Nexstar Pharmaceuticals, Inc. Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties
CA2327469A1 (en) * 1998-04-30 1999-11-04 University Of Cincinnati Fibrinogen coated droplets of liquid hydrophobic phases
EP1046394A3 (en) * 1999-04-19 2001-10-10 ImaRx Pharmaceutical Corp. Novel compositions useful for delivering compounds into a cell
WO2001000174A1 (fr) * 1999-06-25 2001-01-04 Terumo Kabushiki Kaisha Liposomes
DE10109897A1 (de) * 2001-02-21 2002-11-07 Novosom Ag Fakultativ kationische Liposomen und Verwendung dieser
KR20040047747A (ko) * 2001-03-13 2004-06-05 펜웨스트 파머슈티칼즈 컴파니 변시치료 제형
EP1371362A1 (en) * 2002-06-12 2003-12-17 Universiteit Utrecht Holding B.V. Composition for treatment of inflammatory disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0622072A2 (en) * 1993-04-02 1994-11-02 Wakamoto Pharmaceutical Co., Ltd. Stable aqueous dispersions containing liposomes

Also Published As

Publication number Publication date
WO2004047792A3 (de) 2004-08-12
US20060147511A1 (en) 2006-07-06
DE50312034D1 (de) 2009-11-26
JP2006509750A (ja) 2006-03-23
EP1581185B1 (de) 2009-10-14
AU2003294635A1 (en) 2004-06-18
EP1581185A2 (de) 2005-10-05
AU2003294635A2 (en) 2004-06-18
DE10255106A1 (de) 2004-06-09
AU2003294635B2 (en) 2009-05-28
CN1731981B (zh) 2010-06-16
WO2004047792A2 (de) 2004-06-10
CN1731981A (zh) 2006-02-08
ATE445389T1 (de) 2009-10-15
CA2507316A1 (en) 2004-06-10

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20 JUN 2005.

TH Corrigenda

Free format text: IN VOL 23, NO 20, PAGE(S) 8339 UNDER THE HEADING APPLICATIONS ACCEPTED - NAME INDEX UNDER THE NAME NOVOSOM AG, APPLICATION NO. 2003294635, UNDER INID (72) CORRECT THE CO-INVENTOR TO BRAEUER, ROLF

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired