AU2003242233A1 - Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation - Google Patents

Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation

Info

Publication number
AU2003242233A1
AU2003242233A1 AU2003242233A AU2003242233A AU2003242233A1 AU 2003242233 A1 AU2003242233 A1 AU 2003242233A1 AU 2003242233 A AU2003242233 A AU 2003242233A AU 2003242233 A AU2003242233 A AU 2003242233A AU 2003242233 A1 AU2003242233 A1 AU 2003242233A1
Authority
AU
Australia
Prior art keywords
disease
age spots
compound
amyloid accumulation
remedy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003242233A
Other languages
English (en)
Inventor
Yukitsuka Kudo
Nobuyuki Okamura
Hiroshi Shimazu
Tsuyoshi Shiomitsu
Takahiro Suemoto
Masako Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BF Research Institute Inc
Original Assignee
BF Research Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BF Research Institute Inc filed Critical BF Research Institute Inc
Publication of AU2003242233A1 publication Critical patent/AU2003242233A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
AU2003242233A 2002-06-12 2003-06-06 Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation Abandoned AU2003242233A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2002171424 2002-06-12
JP2002171808 2002-06-12
JP2002-171808 2002-06-12
JP2002-171424 2002-06-12
JP2002-378812 2002-12-27
JP2002-378848 2002-12-27
JP2002378812 2002-12-27
JP2002378848 2002-12-27
PCT/JP2003/007183 WO2003106439A1 (ja) 2002-06-12 2003-06-06 アミロイド蓄積性疾患の画像診断プローブ化合物、老人斑／びまん性老人斑染色用化合物、ならびにアミロイド蓄積性疾患の治療薬

Publications (1)

Publication Number Publication Date
AU2003242233A1 true AU2003242233A1 (en) 2003-12-31

Family

ID=29740946

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003242233A Abandoned AU2003242233A1 (en) 2002-06-12 2003-06-06 Probe compound for image diagnosis of disease with amyloid accumulation, compound for staining age spots/diffuse age spots, and remedy for disease with amyloid accumulation

Country Status (2)

Country Link
AU (1) AU2003242233A1 (ja)
WO (1) WO2003106439A1 (ja)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050260126A1 (en) * 2002-08-30 2005-11-24 Yukitsuka Kudo Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein
WO2005016888A1 (ja) * 2003-08-13 2005-02-24 Bf Research Institute, Inc. アミロイド蓄積性疾患のプローブ、アミロイド染色剤、アミロイド蓄積性疾患の治療および予防薬、ならびに神経原線維変化の診断プローブおよび染色剤
TW201018678A (en) 2006-01-27 2010-05-16 Astrazeneca Ab Novel heteroaryl substituted benzothiazoles
JP5182747B2 (ja) * 2006-03-28 2013-04-17 国立大学法人滋賀医科大学 神経難病の画像診断薬
TW200803903A (en) 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
US7700616B2 (en) * 2006-05-08 2010-04-20 Molecular Neuroimaging, Llc. Compounds and amyloid probes thereof for therapeutic and imaging uses
JP5238496B2 (ja) 2006-05-19 2013-07-17 日本メジフィジックス株式会社 新規アミロイド親和性化合物
TW200813035A (en) * 2006-06-19 2008-03-16 Astrazeneca Ab Novel heteroaryl substituted benzoxazoles
CN101501033B (zh) * 2006-06-21 2012-08-01 通用电气医疗有限公司 对淀粉状蛋白具有亲和性的化合物
PE20080888A1 (es) * 2006-10-18 2008-08-26 Novartis Ag COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE LA ACIL-TRANSFERASA DE ACIL-CoA-DIACIL-GLICEROL 1 (DGAT1)
JP5190893B2 (ja) * 2006-12-25 2013-04-24 国立大学法人東北大学 ベンゾキサゾール誘導体
WO2008078424A1 (ja) * 2006-12-25 2008-07-03 Tohoku University ベンゾキサゾール誘導体
TW200901998A (en) 2007-03-06 2009-01-16 Astrazeneca Ab Novel 2-heteroaryl substituted benzothiophenes and benzofuranes
CN101903381A (zh) 2007-10-24 2010-12-01 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物
EP2213671A4 (en) 2007-10-26 2012-02-22 Nihon Mediphysics Co Ltd NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
JPWO2009057578A1 (ja) 2007-10-30 2011-03-10 日本メジフィジックス株式会社 新規アミロイド親和性化合物の使用及び製造方法
JPWO2010087313A1 (ja) * 2009-01-29 2012-08-02 株式会社林原生物化学研究所 神経突起伸展促進剤
WO2010087315A1 (ja) * 2009-01-29 2010-08-05 株式会社林原生物化学研究所 抗アルツハイマー病剤
JP5591720B2 (ja) * 2009-01-29 2014-09-17 株式会社林原 抗神経変性疾患剤
JP2010189359A (ja) * 2009-02-20 2010-09-02 Kyoto Univ ベンゾチアゾール誘導体含有診断用組成物
JP5699286B2 (ja) 2009-02-27 2015-04-08 国立大学法人滋賀医科大学 神経難病の画像診断薬及び体外診断薬
FR2948685A1 (fr) * 2009-07-30 2011-02-04 Biomerieux Sa Nouveaux substrats
CA2818903C (en) 2010-12-14 2021-03-23 Electrophoretics Limited 5-(1,3-benzoxazol-2-yl)-4-(pyridin-4-yl)pyrimidin-2-amine and its use as a casein kinase 1delta inhibitor
JP6367120B2 (ja) 2013-01-09 2018-08-01 国立大学法人滋賀医科大学 神経難病のｍｒ画像診断薬
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬

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JPS5022051B1 (ja) * 1966-02-02 1975-07-28
JPS4946931B1 (ja) * 1970-09-24 1974-12-12
BE792386A (nl) * 1971-12-22 1973-06-07 Agfa Gevaert Nv Supergesensibiliseerde fotografische direct-positieve zilverzout-emulsies
NL174770C (nl) * 1978-09-04 1984-08-01 Hitachi Ltd Elektrofotografische plaat van het complexe type.
JPS5785058A (en) * 1980-11-18 1982-05-27 Hitachi Ltd Composite type electrophotographic plate
JPS58182640A (ja) * 1982-04-20 1983-10-25 Hitachi Ltd 複合型の電子写真用感光体
JPS61129650A (ja) * 1984-11-29 1986-06-17 Canon Inc 積層型電子写真感光体
JPS62161873A (ja) * 1985-07-29 1987-07-17 Sakura Color Prod Corp エチレンオキサイド滅菌標識用インキ組成物
JP3409224B2 (ja) * 1995-02-14 2003-05-26 コニカ株式会社 ハロゲン化銀乳剤
JPH08254786A (ja) * 1995-03-17 1996-10-01 Konica Corp ハロゲン化銀写真乳剤及びハロゲン化銀写真感光材料
WO1997026919A2 (en) * 1996-01-24 1997-07-31 Warner-Lambert Company Method of imaging amyloid deposits
JP2000108513A (ja) * 1998-10-05 2000-04-18 Mitsui Chemicals Inc 光記録媒体
JP4150489B2 (ja) * 2000-06-27 2008-09-17 花王株式会社 染毛剤組成物
PL215711B1 (pl) * 2000-08-24 2014-01-31 Univ Pittsburgh Nowe zwiazki pochodne tioflawiny, sposób syntezy zwiazków i ich zastosowanie, kompozycja farmaceutyczna zawierajaca zwiazki i zastosowanie kompozycji

Also Published As

Publication number Publication date
WO2003106439A1 (ja) 2003-12-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase