AU2003222820A1 - Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification - Google Patents

Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification Download PDF

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Publication number
AU2003222820A1
AU2003222820A1 AU2003222820A AU2003222820A AU2003222820A1 AU 2003222820 A1 AU2003222820 A1 AU 2003222820A1 AU 2003222820 A AU2003222820 A AU 2003222820A AU 2003222820 A AU2003222820 A AU 2003222820A AU 2003222820 A1 AU2003222820 A1 AU 2003222820A1
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Prior art keywords
cell
nucleic acid
disorder
acid molecule
gene
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Abandoned
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AU2003222820A
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Inventor
Karina Drumm
Frank Gohring
Stefan Hubert Schlor
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Acuity Pharmaceuticals Inc
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Acuity Pharmaceuticals Inc
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Publication of AU2003222820A1 publication Critical patent/AU2003222820A1/en
Assigned to ACUITY PHARMACEUTICALS, INC. reassignment ACUITY PHARMACEUTICALS, INC. Request for Assignment Assignors: LYNKEUS BIO TECH GMBH
Priority to AU2009200699A priority Critical patent/AU2009200699A1/en
Abandoned legal-status Critical Current

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2217/00—Genetically modified animals
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    • A01K2217/00—Genetically modified animals
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AU2003222820A 2002-04-18 2003-04-16 Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification Abandoned AU2003222820A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2009200699A AU2009200699A1 (en) 2002-04-18 2009-02-23 Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02008761 2002-04-18
EP02008761.5 2002-04-18
US43117302P 2002-12-05 2002-12-05
US60/431,173 2002-12-05
PCT/EP2003/004003 WO2003087368A2 (en) 2002-04-18 2003-04-16 Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification

Related Child Applications (1)

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AU2009200699A Division AU2009200699A1 (en) 2002-04-18 2009-02-23 Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification

Publications (1)

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AU2003222820A1 true AU2003222820A1 (en) 2003-10-27

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AU2003222820A Abandoned AU2003222820A1 (en) 2002-04-18 2003-04-16 Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification
AU2003224087A Ceased AU2003224087B2 (en) 2002-04-18 2003-04-16 Means and methods for the specific inhibition of genes in cells and tissue of the CNS and/or eye
AU2009200699A Abandoned AU2009200699A1 (en) 2002-04-18 2009-02-23 Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification

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AU2003224087A Ceased AU2003224087B2 (en) 2002-04-18 2003-04-16 Means and methods for the specific inhibition of genes in cells and tissue of the CNS and/or eye
AU2009200699A Abandoned AU2009200699A1 (en) 2002-04-18 2009-02-23 Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification

Country Status (8)

Country Link
US (5) US20050222061A1 (cg-RX-API-DMAC10.html)
EP (2) EP1495120B1 (cg-RX-API-DMAC10.html)
JP (2) JP2006500910A (cg-RX-API-DMAC10.html)
AU (3) AU2003222820A1 (cg-RX-API-DMAC10.html)
CA (2) CA2482903A1 (cg-RX-API-DMAC10.html)
ES (1) ES2397060T3 (cg-RX-API-DMAC10.html)
MX (2) MXPA04010282A (cg-RX-API-DMAC10.html)
WO (2) WO2003087367A2 (cg-RX-API-DMAC10.html)

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