ATE261721T1 - System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung - Google Patents
System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendungInfo
- Publication number
- ATE261721T1 ATE261721T1 AT97927181T AT97927181T ATE261721T1 AT E261721 T1 ATE261721 T1 AT E261721T1 AT 97927181 T AT97927181 T AT 97927181T AT 97927181 T AT97927181 T AT 97927181T AT E261721 T1 ATE261721 T1 AT E261721T1
- Authority
- AT
- Austria
- Prior art keywords
- drug
- nanoparticles
- specific target
- mammalian body
- stabilizers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
- A61K51/1244—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
- A61K51/1251—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1997/003099 WO1998056361A1 (en) | 1997-06-13 | 1997-06-13 | Drug targeting system, method of its preparation and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE261721T1 true ATE261721T1 (de) | 2004-04-15 |
Family
ID=8166655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97927181T ATE261721T1 (de) | 1997-06-13 | 1997-06-13 | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
Country Status (9)
Country | Link |
---|---|
US (1) | US7025991B2 (de) |
EP (1) | EP0986373B1 (de) |
JP (1) | JP3778575B2 (de) |
AT (1) | ATE261721T1 (de) |
AU (1) | AU3176097A (de) |
CA (1) | CA2295177C (de) |
DE (1) | DE69728179T2 (de) |
ES (1) | ES2218685T3 (de) |
WO (1) | WO1998056361A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69728179T2 (de) | 1997-06-13 | 2004-11-25 | Nanodel Technologies Gmbh | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
US7651875B2 (en) * | 1998-06-08 | 2010-01-26 | Borealis Technical Limited | Catalysts |
EP1100475A1 (de) * | 1999-06-02 | 2001-05-23 | Medinova Medical Consulting Gmbh | Verwendung von arzneistoffbeladenen nanopartikel zur behandlung von krebs |
AU5218500A (en) * | 1999-06-22 | 2001-01-09 | Aventis Research & Technologies Gmbh & Co. Kg | Stable, radioactively marked nanoparticles, method for the production and utilization thereof |
WO2001091808A2 (en) * | 2000-06-01 | 2001-12-06 | The Board Of Regents For Oklahoma State University | Bioconjugates of nanoparticles as radiopharmaceuticals |
DE10121982B4 (de) * | 2001-05-05 | 2008-01-24 | Lts Lohmann Therapie-Systeme Ag | Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung |
US20050191359A1 (en) * | 2001-09-28 | 2005-09-01 | Solubest Ltd. | Water soluble nanoparticles and method for their production |
US7763663B2 (en) * | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
US7381426B2 (en) * | 2002-01-24 | 2008-06-03 | Southwest Research Institute | Targeted delivery of bioactive factors to the systemic skeleton |
EP1495121A2 (de) * | 2002-04-18 | 2005-01-12 | Lynkeus Biotech GmbH | Mitteln und verfahren zur spezifischen hemmung von genen in zellen und gewebe vom zns und/oder dem auge |
US7148342B2 (en) | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
DK1526840T3 (da) * | 2002-07-29 | 2008-11-03 | Nanodel Technologies Gmbh | Nanopartikler til DNA administration til et målorgan |
US7618948B2 (en) | 2002-11-26 | 2009-11-17 | Medtronic, Inc. | Devices, systems and methods for improving and/or cognitive function through brain delivery of siRNA |
US20050053668A1 (en) * | 2003-08-21 | 2005-03-10 | Southwest Research Institute | Skeletally targeted nanoparticles |
WO2005077337A2 (en) * | 2004-02-05 | 2005-08-25 | Baxter International Inc. | Dispersions prepared by use of self-stabilizing agents |
ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
WO2006029845A2 (en) * | 2004-09-14 | 2006-03-23 | Nanodel Technologies Gmbh | Delivery vehicle containing nanoparticles |
EP1661559A1 (de) * | 2004-11-25 | 2006-05-31 | NanoDel Technologies GmbH | Verabreichungssystem hergestellt durch ein Miniemulsionsverfahren |
WO2006056362A2 (en) * | 2004-11-25 | 2006-06-01 | Nanodel Technologies Gmbh | Delivery vehicle manufactured by the miniemulsion method |
US20090280064A1 (en) * | 2005-06-24 | 2009-11-12 | Rao Papineni | Transdermal delivery of optical, spect, multimodal, drug or biological cargo laden nanoparticle(s) in small animals or humans |
US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
US20090304599A1 (en) * | 2005-12-20 | 2009-12-10 | Fujifilm Corporation | Protein Nanoparticles and the Use of the Same |
EP1815851A1 (de) * | 2006-02-03 | 2007-08-08 | NanoDel Technologies GmbH | Nanopartikel zur Arzneistoffverabreichung |
DE102006013531A1 (de) | 2006-03-24 | 2007-09-27 | Lts Lohmann Therapie-Systeme Ag | Polylactid-Nanopartikel |
US20070231360A1 (en) * | 2006-03-28 | 2007-10-04 | Minu, L.L.C. | Neural conduit agent dissemination |
ATE510538T1 (de) | 2006-08-11 | 2011-06-15 | Univ Johns Hopkins | Zusammensetzungen und verfahren für nervenschutz |
US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
JP5201763B2 (ja) * | 2007-02-28 | 2013-06-05 | 昇一 城武 | 異なる平均粒径サイズの粒子からなる混合微粒子カプセルの製造方法 |
US20090061009A1 (en) * | 2007-08-29 | 2009-03-05 | Joseph Schwarz | Composition and Method of Treatment of Bacterial Infections |
EA201001568A1 (ru) * | 2008-05-06 | 2011-10-31 | Глаксо Груп Лимитед | Инкапсуляция биологически активных агентов |
US8470792B2 (en) | 2008-12-04 | 2013-06-25 | Opko Pharmaceuticals, Llc. | Compositions and methods for selective inhibition of VEGF |
US10105317B2 (en) * | 2009-07-07 | 2018-10-23 | Anpac Bio-Medical Science Co., Ltd. | Method of drug delivery |
US8828246B2 (en) * | 2010-02-18 | 2014-09-09 | Anpac Bio-Medical Science Co., Ltd. | Method of fabricating micro-devices |
PL2560624T3 (pl) * | 2010-04-23 | 2019-01-31 | Kempharm, Inc. | Formulacja terapeutyczna do zmniejszania skutków ubocznych leku |
US10555911B2 (en) | 2012-05-04 | 2020-02-11 | Yale University | Highly penetrative nanocarriers for treatment of CNS disease |
US10967039B2 (en) | 2013-05-28 | 2021-04-06 | Sintef Tto As | Process for preparing stealth nanoparticles |
CN117731591A (zh) | 2016-11-21 | 2024-03-22 | 艾里奥治疗公司 | 大试剂的透皮递送 |
KR20190097729A (ko) * | 2018-02-13 | 2019-08-21 | 서강대학교산학협력단 | 안질환 치료용 약물 전달 임플란트 및 이의 제조방법 |
BR112021003121A2 (pt) | 2018-08-23 | 2021-05-11 | Sintef Tto As | nanopartículas |
EP3952836A1 (de) | 2019-04-10 | 2022-02-16 | Sintef Tto As | Nanopartikel mit copolymeren oder homopolymeren verbindungen, die cyanoacrylatuntereinheiten enthalten |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2634397B2 (fr) | 1986-12-31 | 1991-04-19 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une proteine sous forme de nanoparticules |
FR2612400A1 (fr) | 1987-03-16 | 1988-09-23 | Centre Nat Rech Scient | Microcapsules contenant un marqueur radioactif et/ou paramagnetique sous forme de chelate, et leur utilisation dans le domaine de l'imagerie medicale |
JP2670680B2 (ja) * | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
IT1243390B (it) * | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
WO1994015590A1 (en) * | 1993-01-11 | 1994-07-21 | Abacol Limited | Small diameter nanocapsules, process for their preparation and applications thereof |
TW355683B (en) * | 1994-02-17 | 1999-04-11 | Janssen Pharmaceutica Nv | Composition containing micronized nebivolol |
ES2188652T3 (es) | 1994-02-28 | 2003-07-01 | Nanopharm Ag | Sistema de direccionado de farmacos, metodos de fabricacion y uso del mismo. |
US5837221A (en) * | 1996-07-29 | 1998-11-17 | Acusphere, Inc. | Polymer-lipid microencapsulated gases for use as imaging agents |
DE69728179T2 (de) | 1997-06-13 | 2004-11-25 | Nanodel Technologies Gmbh | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
DE19745950A1 (de) | 1997-10-17 | 1999-04-22 | Dds Drug Delivery Service Ges | Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation |
EP1100475A1 (de) | 1999-06-02 | 2001-05-23 | Medinova Medical Consulting Gmbh | Verwendung von arzneistoffbeladenen nanopartikel zur behandlung von krebs |
-
1997
- 1997-06-13 DE DE69728179T patent/DE69728179T2/de not_active Expired - Fee Related
- 1997-06-13 AT AT97927181T patent/ATE261721T1/de not_active IP Right Cessation
- 1997-06-13 WO PCT/EP1997/003099 patent/WO1998056361A1/en active IP Right Grant
- 1997-06-13 JP JP50135999A patent/JP3778575B2/ja not_active Expired - Fee Related
- 1997-06-13 CA CA002295177A patent/CA2295177C/en not_active Expired - Fee Related
- 1997-06-13 EP EP97927181A patent/EP0986373B1/de not_active Expired - Lifetime
- 1997-06-13 ES ES97927181T patent/ES2218685T3/es not_active Expired - Lifetime
- 1997-06-13 AU AU31760/97A patent/AU3176097A/en not_active Abandoned
- 1997-06-13 US US09/445,439 patent/US7025991B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP3778575B2 (ja) | 2006-05-24 |
JP2001502721A (ja) | 2001-02-27 |
EP0986373B1 (de) | 2004-03-17 |
US7025991B2 (en) | 2006-04-11 |
EP0986373A1 (de) | 2000-03-22 |
DE69728179D1 (de) | 2004-04-22 |
AU3176097A (en) | 1998-12-30 |
DE69728179T2 (de) | 2004-11-25 |
CA2295177C (en) | 2007-01-09 |
US20020034474A1 (en) | 2002-03-21 |
ES2218685T3 (es) | 2004-11-16 |
CA2295177A1 (en) | 1998-12-17 |
WO1998056361A1 (en) | 1998-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |