AU2003213684C1 - Methods of inducing terminal differentiation - Google Patents
Methods of inducing terminal differentiation Download PDFInfo
- Publication number
- AU2003213684C1 AU2003213684C1 AU2003213684A AU2003213684A AU2003213684C1 AU 2003213684 C1 AU2003213684 C1 AU 2003213684C1 AU 2003213684 A AU2003213684 A AU 2003213684A AU 2003213684 A AU2003213684 A AU 2003213684A AU 2003213684 C1 AU2003213684 C1 AU 2003213684C1
- Authority
- AU
- Australia
- Prior art keywords
- saha
- pharmaceutically acceptable
- hydrate
- acceptable salt
- hydroxamic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired, expires
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
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- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
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- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2007203525A AU2007203525C1 (en) | 2002-03-04 | 2007-07-26 | Methods of Inducing Terminal Differentiation |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36175902P | 2002-03-04 | 2002-03-04 | |
| US60/361,759 | 2002-03-04 | ||
| PCT/US2003/006451 WO2003075839A2 (en) | 2002-03-04 | 2003-03-04 | Methods of inducing terminal differentiation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007203525A Division AU2007203525C1 (en) | 2002-03-04 | 2007-07-26 | Methods of Inducing Terminal Differentiation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2003213684A1 AU2003213684A1 (en) | 2003-09-22 |
| AU2003213684B2 AU2003213684B2 (en) | 2007-04-26 |
| AU2003213684C1 true AU2003213684C1 (en) | 2008-10-23 |
Family
ID=27805074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003213684A Expired AU2003213684C1 (en) | 2002-03-04 | 2003-03-04 | Methods of inducing terminal differentiation |
Country Status (17)
| Country | Link |
|---|---|
| US (7) | US20040072735A1 (enExample) |
| EP (4) | EP1487426B1 (enExample) |
| JP (4) | JP4732693B2 (enExample) |
| KR (2) | KR100892016B1 (enExample) |
| CN (3) | CN103393630A (enExample) |
| AU (1) | AU2003213684C1 (enExample) |
| BR (1) | BR0308250A (enExample) |
| CA (3) | CA2671976C (enExample) |
| ES (1) | ES2532607T3 (enExample) |
| IL (3) | IL163909A0 (enExample) |
| MX (1) | MXPA04008577A (enExample) |
| NO (2) | NO329984B1 (enExample) |
| NZ (3) | NZ550185A (enExample) |
| PL (1) | PL372239A1 (enExample) |
| RU (3) | RU2394022C2 (enExample) |
| WO (1) | WO2003075839A2 (enExample) |
| ZA (2) | ZA200407942B (enExample) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6777217B1 (en) | 1996-03-26 | 2004-08-17 | President And Fellows Of Harvard College | Histone deacetylases, and uses related thereto |
| US20030129724A1 (en) * | 2000-03-03 | 2003-07-10 | Grozinger Christina M. | Class II human histone deacetylases, and uses related thereto |
| US7244853B2 (en) | 2001-05-09 | 2007-07-17 | President And Fellows Of Harvard College | Dioxanes and uses thereof |
| ATE517624T1 (de) * | 2001-10-16 | 2011-08-15 | Sloan Kettering Inst Cancer | Behandlung von neurodegenerativen erkrankungen und krebs im gehirn |
| EP1482962A4 (en) * | 2002-02-15 | 2009-12-23 | Sloan Kettering Inst Cancer | METHOD OF TREATING THIOREDOXIN-MEDIATED DISEASES (TRX) |
| US20070060614A1 (en) * | 2002-03-04 | 2007-03-15 | Bacopoulos Nicholas G | Methods of treating cancer with hdac inhibitors |
| US7456219B2 (en) * | 2002-03-04 | 2008-11-25 | Merck Hdac Research, Llc | Polymorphs of suberoylanilide hydroxamic acid |
| RU2394022C2 (ru) * | 2002-03-04 | 2010-07-10 | МЕРК ЭйчДиЭйСи Рисерч, ЛЛС | Способы индукции конечной дифференцировки |
| US7148257B2 (en) | 2002-03-04 | 2006-12-12 | Merck Hdac Research, Llc | Methods of treating mesothelioma with suberoylanilide hydroxamic acid |
| US20060276547A1 (en) * | 2002-03-04 | 2006-12-07 | Bacopoulos Nicholas G | Methods of treating cancer with HDAC inhibitors |
| US20040132825A1 (en) * | 2002-03-04 | 2004-07-08 | Bacopoulos Nicholas G. | Methods of treating cancer with HDAC inhibitors |
| TWI319387B (en) | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
| MXPA04010199A (es) * | 2002-04-15 | 2005-07-05 | Sloan Kettering Inst Cancer | Terapia en combinacion para el tratamiento de cancer. |
| TW559390U (en) * | 2002-08-27 | 2003-10-21 | Molex Inc | Electrical connector |
| US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| FR2847817B1 (fr) * | 2002-11-28 | 2006-11-10 | Centre Nat Rech Scient | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
| US7375228B2 (en) | 2003-03-17 | 2008-05-20 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| JP2006523693A (ja) * | 2003-04-01 | 2006-10-19 | メモリアル スローン−ケタリング キャンサー センター | ヒドロキサム酸化合物およびその使用方法 |
| NZ544756A (en) | 2003-07-22 | 2009-09-25 | Astex Therapeutics Ltd | 3,4-Disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinases (CDK) and glycogen synthase kinase-3 (GSK-3) modulators |
| KR20050022216A (ko) * | 2003-08-25 | 2005-03-07 | 윤덕구 | 동결건조 즉석소면 및 그 제조방법 |
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| US6451334B2 (en) * | 1997-05-30 | 2002-09-17 | Susan P. Perrine | Compositions and administration of compositions for the treatment of blood disorders |
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