FR2847817B1 - Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires - Google Patents
Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculairesInfo
- Publication number
- FR2847817B1 FR2847817B1 FR0214980A FR0214980A FR2847817B1 FR 2847817 B1 FR2847817 B1 FR 2847817B1 FR 0214980 A FR0214980 A FR 0214980A FR 0214980 A FR0214980 A FR 0214980A FR 2847817 B1 FR2847817 B1 FR 2847817B1
- Authority
- FR
- France
- Prior art keywords
- treatment
- histone deacetylase
- deacetylase inhibitor
- muscle dystrophies
- dystrophies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0214980A FR2847817B1 (fr) | 2002-11-28 | 2002-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
CA2507450A CA2507450C (fr) | 2002-11-28 | 2003-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
EP03789530A EP1565175A1 (fr) | 2002-11-28 | 2003-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
AU2003294110A AU2003294110A1 (en) | 2002-11-28 | 2003-11-28 | Use of a histone deacetylase inhibitor for treating muscular dystrophies |
PCT/FR2003/003530 WO2004050076A1 (fr) | 2002-11-28 | 2003-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
US10/536,417 US20060148684A1 (en) | 2002-11-28 | 2003-11-28 | Use of a histone deacetylase inhibitor for treating muscular dystrophies |
US12/006,497 US20080160108A1 (en) | 2002-11-28 | 2008-01-03 | Method of treating muscular dystrophies with an inhibitor of histone deacetylase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0214980A FR2847817B1 (fr) | 2002-11-28 | 2002-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2847817A1 FR2847817A1 (fr) | 2004-06-04 |
FR2847817B1 true FR2847817B1 (fr) | 2006-11-10 |
Family
ID=32309803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0214980A Expired - Fee Related FR2847817B1 (fr) | 2002-11-28 | 2002-11-28 | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires |
Country Status (6)
Country | Link |
---|---|
US (2) | US20060148684A1 (fr) |
EP (1) | EP1565175A1 (fr) |
AU (1) | AU2003294110A1 (fr) |
CA (1) | CA2507450C (fr) |
FR (1) | FR2847817B1 (fr) |
WO (1) | WO2004050076A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008029152A2 (fr) * | 2006-09-08 | 2008-03-13 | Summit Corporation Plc | Traitement de la dystrophie musculaire de duchenne |
US20120010176A1 (en) * | 2008-11-12 | 2012-01-12 | Khurana Tejvir S | Utrophin promoter activity upregulation for the treatment of muscular dystrophy |
WO2010086040A1 (fr) * | 2009-01-29 | 2010-08-05 | Biomarin Iga, Ltd. | Pyrazolo-pyrimidines pour traitement de la myopathie de duchenne |
US20140147434A1 (en) * | 2011-05-06 | 2014-05-29 | Ecole Polytechnique Federale De Lausanne (Epfl) | NCoR1 is a Physiological Modulator of Muscle Mass and Oxidative Function |
CN107007580A (zh) * | 2012-02-03 | 2017-08-04 | 意大发马克股份公司 | 用于治疗肌肉萎缩症的化合物 |
FR2993461B1 (fr) * | 2012-07-19 | 2014-08-08 | Genethon | Utilisation de composes modifiant l'epigenome pour le traitement des maladies genetiques musculaires liees a une anomalie de conformation proteique |
WO2023278684A1 (fr) * | 2021-06-30 | 2023-01-05 | Massachusetts Institute Of Technology | Compositions et méthodes de traitement de la dysferlinopathie |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5439939A (en) * | 1992-03-17 | 1995-08-08 | Children's Hospital Medical Center Of Northern California | Pharmaceutical compositions and methods using isobutyramide for treating betaglobin disorders |
CZ20011342A3 (cs) * | 1998-10-13 | 2001-09-12 | Fujisawa Pharmaceutical Co., Ltd. | Cyklické tetrapeptidy |
AU3757600A (en) * | 1999-03-19 | 2000-10-09 | Vertex Pharmaceuticals Incorporated | Oral low dose butyrate compositions |
FR2794647A1 (fr) * | 1999-06-11 | 2000-12-15 | Centre Nat Rech Scient | Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules |
US6376508B1 (en) * | 2000-12-13 | 2002-04-23 | Academia Sinica | Treatments for spinal muscular atrophy |
US6720445B2 (en) * | 2000-12-21 | 2004-04-13 | Beacon Laboratories, Inc. | Acetyloxymethyl esters and methods for using the same |
US6495719B2 (en) * | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
EP2082737B1 (fr) * | 2002-03-04 | 2014-12-31 | Merck HDAC Research, LLC | Procédés d'induction de différentiation de terminal |
-
2002
- 2002-11-28 FR FR0214980A patent/FR2847817B1/fr not_active Expired - Fee Related
-
2003
- 2003-11-28 US US10/536,417 patent/US20060148684A1/en not_active Abandoned
- 2003-11-28 CA CA2507450A patent/CA2507450C/fr not_active Expired - Fee Related
- 2003-11-28 EP EP03789530A patent/EP1565175A1/fr not_active Withdrawn
- 2003-11-28 WO PCT/FR2003/003530 patent/WO2004050076A1/fr not_active Application Discontinuation
- 2003-11-28 AU AU2003294110A patent/AU2003294110A1/en not_active Abandoned
-
2008
- 2008-01-03 US US12/006,497 patent/US20080160108A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2507450C (fr) | 2014-07-08 |
US20080160108A1 (en) | 2008-07-03 |
AU2003294110A1 (en) | 2004-06-23 |
CA2507450A1 (fr) | 2004-06-17 |
FR2847817A1 (fr) | 2004-06-04 |
US20060148684A1 (en) | 2006-07-06 |
WO2004050076A1 (fr) | 2004-06-17 |
EP1565175A1 (fr) | 2005-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL164007A0 (en) | New inhibitors of histone deacetylase | |
FR22C1033I1 (fr) | Utilisation de dihydroimidazolones pour le traitement des chiens | |
IL164659A0 (en) | Inhibitors of histone deacetylase | |
EE200200062A (et) | Monoaminoksüdaasi inhibiitorite kasutamine ravimite valmistamiseks rasvumuse raviks | |
CY2015053I2 (el) | Υδροξαμικα παραγωγα χρησιμα ως αναστολεις δεακετυλασης | |
IL164002A0 (en) | Sulfonyl-derivatives as novel inhibitors of histone deacetylase | |
HK1080465A1 (zh) | 作為組蛋白脫乙酰酶新穎抑制劑的磺酰基氨基衍生物 | |
EG25655A (en) | Benzamide derivatives useful as histone deacetylase inhibitors | |
PL349900A1 (en) | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors | |
NO20014047D0 (no) | Monoamin reopptaksinhibitorer for behandling av CNS forstyrrelser | |
PL374970A1 (en) | Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors | |
AU2003219595A8 (en) | Alpha,beta-unsaturated hydroxamic acid derivatives and their use as histone deacetylase inhibitors | |
HUP0402370A3 (en) | Pharmaceutical compositions containing cyclooxigenase-2 inhibitor and histone deacetylase inhibitor combination | |
GB0226855D0 (en) | Histone deacetylase inhibitors | |
AU2003255413A8 (en) | Use of lck inhibitor for treatment of immunologic diseases | |
EP1560583A4 (fr) | Inhibiteurs de l'histone desacetylase pour le traitement de maladies et de troubles oculaires, neovasculaires ou oedemateux | |
FR2847817B1 (fr) | Utilisation d'un inhibiteur d'histone deacetylase pour le traitement des dystrophies musculaires | |
FR2848844B1 (fr) | Utilisation d'un alkylether d'hydroxystilbene pour le traitement des peaux seches | |
NO20032183L (no) | Histon-deacetylase-inhibitor og anvendelse derav | |
SI1569634T1 (sl) | Uporaba PPAR-alfa agonista in metformina za zdravljenje obezitete | |
IL147363A0 (en) | Ppar delta inhibitor for the treatment of cardiovascular diseases | |
FR2834887B1 (fr) | Utilisation d'un extrait d'artemia pour le traitement des peaux agees | |
ID20794A (id) | Penggunaan inhibitor penukar natrium-hidrogen untuk pembuatan sediaan farmasi untuk pengobatan gangguan yang disebabkan oleh protozoa | |
GB0202187D0 (en) | "Inhibitors" | |
TWI346661B (en) | Inhibitors of histone deacetylase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 14 |
|
ST | Notification of lapse |
Effective date: 20170731 |