AU2002342694B2 - Ophthalmic depot formulations for periocular or subconjunctival administration - Google Patents

Ophthalmic depot formulations for periocular or subconjunctival administration Download PDF

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Publication number
AU2002342694B2
AU2002342694B2 AU2002342694A AU2002342694A AU2002342694B2 AU 2002342694 B2 AU2002342694 B2 AU 2002342694B2 AU 2002342694 A AU2002342694 A AU 2002342694A AU 2002342694 A AU2002342694 A AU 2002342694A AU 2002342694 B2 AU2002342694 B2 AU 2002342694B2
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AU
Australia
Prior art keywords
active agent
formulation according
microparticles
polymer
time
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002342694A
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English (en)
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AU2002342694A1 (en
Inventor
Markus Ahlheim
Michael Ausborn
David Bodmer
Christian Schoch
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Novartis AG
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Novartis AG
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Publication of AU2002342694A1 publication Critical patent/AU2002342694A1/en
Application granted granted Critical
Publication of AU2002342694B2 publication Critical patent/AU2002342694B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2002342694A 2001-09-14 2002-09-13 Ophthalmic depot formulations for periocular or subconjunctival administration Ceased AU2002342694B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0122318.9 2001-09-14
GBGB0122318.9A GB0122318D0 (en) 2001-09-14 2001-09-14 Organic compounds
PCT/EP2002/010314 WO2003024420A1 (en) 2001-09-14 2002-09-13 Ophthalmic depot formulations for periocular or subconjunctival administration

Publications (2)

Publication Number Publication Date
AU2002342694A1 AU2002342694A1 (en) 2003-06-05
AU2002342694B2 true AU2002342694B2 (en) 2006-08-24

Family

ID=9922147

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002342694A Ceased AU2002342694B2 (en) 2001-09-14 2002-09-13 Ophthalmic depot formulations for periocular or subconjunctival administration

Country Status (24)

Country Link
US (4) US20040234611A1 (enExample)
EP (1) EP1429725B1 (enExample)
JP (3) JP2005504797A (enExample)
KR (1) KR20040030869A (enExample)
CN (2) CN102008428A (enExample)
AT (1) ATE389385T1 (enExample)
AU (1) AU2002342694B2 (enExample)
BR (1) BR0212475A (enExample)
CA (1) CA2455680C (enExample)
CO (1) CO5560548A2 (enExample)
DE (1) DE60225701T2 (enExample)
EC (1) ECSP044967A (enExample)
ES (1) ES2302849T3 (enExample)
GB (1) GB0122318D0 (enExample)
HU (1) HU229453B1 (enExample)
IL (2) IL160027A0 (enExample)
MX (1) MXPA04002421A (enExample)
NO (1) NO333825B1 (enExample)
NZ (1) NZ531481A (enExample)
PL (1) PL203949B1 (enExample)
PT (1) PT1429725E (enExample)
RU (1) RU2316315C2 (enExample)
WO (1) WO2003024420A1 (enExample)
ZA (1) ZA200400524B (enExample)

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HU229453B1 (en) 2013-12-30
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BR0212475A (pt) 2004-08-24
JP2011026338A (ja) 2011-02-10
KR20040030869A (ko) 2004-04-09
PT1429725E (pt) 2008-06-18
NZ531481A (en) 2005-12-23
NO333825B1 (no) 2013-09-23
HK1066733A1 (en) 2005-04-01
US20120269894A1 (en) 2012-10-25
JP2005504797A (ja) 2005-02-17
HUP0401568A2 (hu) 2004-11-29
NO20040917L (no) 2004-03-02
CN102008428A (zh) 2011-04-13
GB0122318D0 (en) 2001-11-07
ATE389385T1 (de) 2008-04-15
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RU2316315C2 (ru) 2008-02-10
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US20080305172A1 (en) 2008-12-11
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