AU2001287291B2 - Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma - Google Patents

Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma Download PDF

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Publication number
AU2001287291B2
AU2001287291B2 AU2001287291A AU2001287291A AU2001287291B2 AU 2001287291 B2 AU2001287291 B2 AU 2001287291B2 AU 2001287291 A AU2001287291 A AU 2001287291A AU 2001287291 A AU2001287291 A AU 2001287291A AU 2001287291 B2 AU2001287291 B2 AU 2001287291B2
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Australia
Prior art keywords
antibody
cytokine
cell
patient
antagonist
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Ceased
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AU2001287291A
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AU2001287291A1 (en
Inventor
Nabil Hanna
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Biogen Inc
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Biogen Idec Inc
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Assigned to BIOGEN IDEC INC. reassignment BIOGEN IDEC INC. Request for Assignment Assignors: IDEC PHARMACEUTICALS CORPORATION
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001287291A 2000-03-31 2001-04-02 Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma Ceased AU2001287291B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19346700P 2000-03-31 2000-03-31
US60/193,467 2000-03-31
PCT/US2001/010382 WO2001074388A1 (en) 2000-03-31 2001-04-02 Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma

Publications (2)

Publication Number Publication Date
AU2001287291A1 AU2001287291A1 (en) 2002-01-03
AU2001287291B2 true AU2001287291B2 (en) 2006-08-10

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001287291A Ceased AU2001287291B2 (en) 2000-03-31 2001-04-02 Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma
AU8729101A Pending AU8729101A (en) 2000-03-31 2001-04-02 Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU8729101A Pending AU8729101A (en) 2000-03-31 2001-04-02 Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma

Country Status (12)

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US (2) US6896885B2 (enExample)
EP (1) EP1283722A1 (enExample)
JP (1) JP2004500412A (enExample)
KR (1) KR20020091170A (enExample)
CN (2) CN1441677A (enExample)
AU (2) AU2001287291B2 (enExample)
BR (1) BR0109705A (enExample)
CA (1) CA2404365A1 (enExample)
MX (1) MXPA02009626A (enExample)
NO (1) NO20024682L (enExample)
WO (1) WO2001074388A1 (enExample)
ZA (1) ZA200207847B (enExample)

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US20050180975A1 (en) 2005-08-18
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