AU2001274109B2 - Method of administering bisphosphonates - Google Patents

Method of administering bisphosphonates Download PDF

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Publication number
AU2001274109B2
AU2001274109B2 AU2001274109A AU2001274109A AU2001274109B2 AU 2001274109 B2 AU2001274109 B2 AU 2001274109B2 AU 2001274109 A AU2001274109 A AU 2001274109A AU 2001274109 A AU2001274109 A AU 2001274109A AU 2001274109 B2 AU2001274109 B2 AU 2001274109B2
Authority
AU
Australia
Prior art keywords
diphosphonic acid
ethane
hydroxy
administrations
period
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2001274109A
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English (en)
Other versions
AU2001274109A1 (en
Inventor
Zebulun D. Horowitz
Peter C. Richardson
Ulrich Trechsel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26952565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001274109(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2001274109A1 publication Critical patent/AU2001274109A1/en
Application granted granted Critical
Publication of AU2001274109B2 publication Critical patent/AU2001274109B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001274109A 2000-06-20 2001-06-18 Method of administering bisphosphonates Expired AU2001274109B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US59713500A 2000-06-20 2000-06-20
US09/597,135 2000-06-20
US26768901P 2001-02-09 2001-02-09
US60/267,689 2001-02-09
PCT/EP2001/006850 WO2001097788A2 (en) 2000-06-20 2001-06-18 Method of administering bisphosphonates

Publications (2)

Publication Number Publication Date
AU2001274109A1 AU2001274109A1 (en) 2002-03-21
AU2001274109B2 true AU2001274109B2 (en) 2004-12-23

Family

ID=26952565

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001274109A Expired AU2001274109B2 (en) 2000-06-20 2001-06-18 Method of administering bisphosphonates
AU7410901A Pending AU7410901A (en) 2000-06-20 2001-06-18 Method of administering bisphosphonates

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU7410901A Pending AU7410901A (en) 2000-06-20 2001-06-18 Method of administering bisphosphonates

Country Status (24)

Country Link
US (1) US8052987B2 (enExample)
EP (1) EP1296689B3 (enExample)
JP (2) JP4722375B2 (enExample)
KR (1) KR100864743B1 (enExample)
CN (1) CN1272013C (enExample)
AT (1) ATE304856T1 (enExample)
AU (2) AU2001274109B2 (enExample)
BR (1) BR0111806A (enExample)
CA (1) CA2410201C (enExample)
CY (2) CY1113740T1 (enExample)
CZ (1) CZ301972B6 (enExample)
DE (1) DE60113537T3 (enExample)
DK (1) DK1296689T3 (enExample)
ES (2) ES2394211T3 (enExample)
HU (1) HU228400B1 (enExample)
IL (2) IL153229A0 (enExample)
MX (1) MXPA02012682A (enExample)
NO (1) NO330459B1 (enExample)
NZ (1) NZ523086A (enExample)
PL (1) PL203087B1 (enExample)
PT (1) PT1591122E (enExample)
SK (1) SK287278B6 (enExample)
TW (1) TWI289451B (enExample)
WO (1) WO2001097788A2 (enExample)

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TW200410701A (en) * 2002-10-15 2004-07-01 Novartis Ag Method of administering bisphosphonates
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US7473684B2 (en) * 2005-09-16 2009-01-06 Selamine Limited Bisphosphonate formulation
CA2648594C (en) * 2006-04-07 2012-10-16 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
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AR075613A1 (es) * 2009-02-25 2011-04-20 Merrion Res Iii Ltd Composicion y suministro de drogas de bifosfonato. metodo de tratamiento
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US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
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US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
US9089484B2 (en) * 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
WO2012071517A2 (en) 2010-11-24 2012-05-31 Thar Pharmaceuticals, Inc. Novel crystalline forms
JP2014501784A (ja) 2011-01-07 2014-01-23 メリオン・リサーチ・Iii・リミテッド 経口投与用の鉄の医薬組成物
CA2856030A1 (en) 2011-11-16 2013-05-23 Duke University Bisphosphonate compositions and methods for treating and/or reducing cardiac dysfunction
CN103623465B (zh) * 2013-11-21 2015-12-30 彭江 一种可局部调节成破骨活性的组织工程骨支架及制备方法
JP7211704B2 (ja) 2015-01-29 2023-01-24 ノヴォ ノルディスク アー/エス Glp-1アゴニスト及び腸溶コーティングを含む錠剤
US10195218B2 (en) 2016-05-31 2019-02-05 Grunenthal Gmbh Crystallization method and bioavailability
KR20180115979A (ko) * 2017-04-14 2018-10-24 연세대학교 산학협력단 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물
GB201716716D0 (en) 2017-10-12 2017-11-29 Univ Of Hertfordshire Higher Education Corporation Method for coating particles
CA3118311A1 (en) * 2018-11-02 2020-05-07 Ampersand Biopharmaceuticals, Inc. Management of risk of cation overload and electrolyte imbalance with topically applied buffers
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Also Published As

Publication number Publication date
EP1296689B3 (en) 2013-02-13
EP1296689A2 (en) 2003-04-02
KR20030015283A (ko) 2003-02-20
HK1072539A1 (en) 2005-09-02
NO330459B1 (no) 2011-04-18
CZ20024134A3 (cs) 2003-06-18
PL358224A1 (en) 2004-08-09
CA2410201C (en) 2010-10-26
PT1591122E (pt) 2012-12-12
WO2001097788A2 (en) 2001-12-27
AU7410901A (en) 2002-01-02
JP4722375B2 (ja) 2011-07-13
CY1113740T1 (el) 2015-08-05
ES2394211T3 (es) 2013-01-23
ES2247123T3 (es) 2006-03-01
MXPA02012682A (es) 2003-04-25
CZ301972B6 (cs) 2010-08-18
IL153229A0 (en) 2003-07-06
BR0111806A (pt) 2003-05-20
KR100864743B1 (ko) 2008-10-22
SK18082002A3 (sk) 2003-08-05
ES2247123T7 (es) 2013-03-01
SK287278B6 (sk) 2010-05-07
EP1296689B1 (en) 2005-09-21
DE60113537T2 (de) 2006-06-29
TWI289451B (en) 2007-11-11
IL153229A (en) 2007-07-24
PL203087B1 (pl) 2009-08-31
US8052987B2 (en) 2011-11-08
DE60113537D1 (de) 2006-02-02
JP2005247873A (ja) 2005-09-15
HUP0301164A3 (en) 2005-11-28
CN1620300A (zh) 2005-05-25
CY2013011I2 (el) 2015-08-05
JP2003535889A (ja) 2003-12-02
ATE304856T1 (de) 2005-10-15
DK1296689T3 (da) 2005-11-28
CN1272013C (zh) 2006-08-30
WO2001097788A3 (en) 2002-06-27
HU228400B1 (en) 2013-03-28
CA2410201A1 (en) 2001-12-27
NO20026117L (no) 2002-12-19
NZ523086A (en) 2007-07-27
DE60113537T3 (de) 2013-05-29
HUP0301164A2 (hu) 2003-08-28
JP5005188B2 (ja) 2012-08-22
CY2013011I1 (el) 2015-08-05
NO20026117D0 (no) 2002-12-19
US20030181421A1 (en) 2003-09-25

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DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 19 JUL 2012 .

DA6 Amendments section 104, application for amendment withdrawn
MK14 Patent ceased section 143(a) (annual fees not paid) or expired