AR075613A1 - Composicion y suministro de drogas de bifosfonato. metodo de tratamiento - Google Patents
Composicion y suministro de drogas de bifosfonato. metodo de tratamientoInfo
- Publication number
- AR075613A1 AR075613A1 ARP100100559A ARP100100559A AR075613A1 AR 075613 A1 AR075613 A1 AR 075613A1 AR P100100559 A ARP100100559 A AR P100100559A AR P100100559 A ARP100100559 A AR P100100559A AR 075613 A1 AR075613 A1 AR 075613A1
- Authority
- AR
- Argentina
- Prior art keywords
- cancer
- enhancer
- bisphosphonate
- pharmaceutical composition
- subject
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Reivindicacion 1: Un método para tratar o prevenir en un sujeto una afeccion médica que responde a un compuesto de bifosfonato, caracterizado porque comprende: administrarle al sujeto una composicion farmacéutica que comprende una cantidad terapéutica eficaz de bifosfonato con una frecuencia no menor a un régimen de dosificacion quincenal, en donde el compuesto de bifosfonato es ácido zoledronico. Reivindicacion 16: El método de acuerdo con cualquiera de las reivindicaciones 1 a 12, caracterizado porque la afeccion médica se selecciona del grupo que consiste en lupus eritematoso sistémico (SLE), cáncer, hipocalcemia inducida por tumor, metástasis osea y una combinacion de éstos. Reivindicacion 17: El método de acuerdo con la reivindicacion 16, caracterizado porque el cáncer se selecciona del grupo que consiste en cáncer de prostata, cáncer oseo metastásico, cáncer de pulmon, mieloma multiple, cáncer de mama y cualquier otro tumor solido que induce una enfermedad metastásica. Reivindicacion 21: El método de acuerdo con cualquiera de las reivindicaciones 1 a 20, caracterizado porque la composicion farmacéutica también comprende un mejorador, en donde dicho mejorador es una sal de ácido graso de cadena media, un éster, un éter o un derivado de un ácido graso de cadena media y tiene una longitud de cadena de carbono de alrededor de 4 a alrededor de 20 átomos de carbono.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15526909P | 2009-02-25 | 2009-02-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR075613A1 true AR075613A1 (es) | 2011-04-20 |
Family
ID=42631176
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100100559A AR075613A1 (es) | 2009-02-25 | 2010-02-25 | Composicion y suministro de drogas de bifosfonato. metodo de tratamiento |
Country Status (7)
Country | Link |
---|---|
US (1) | US20100215743A1 (es) |
EP (1) | EP2400851A4 (es) |
JP (2) | JP2012518686A (es) |
AR (1) | AR075613A1 (es) |
CA (1) | CA2751854A1 (es) |
TW (1) | TWI480286B (es) |
WO (1) | WO2010099255A1 (es) |
Families Citing this family (79)
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US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US7704977B2 (en) | 2006-04-07 | 2010-04-27 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
WO2009137078A1 (en) * | 2008-05-07 | 2009-11-12 | Merrion Research Iii Limited | Compositions of peptides and processes of preparation thereof |
JP5852569B2 (ja) | 2009-07-31 | 2016-02-03 | タール ファーマシューティカルズ,インコーポレイテッド | 結晶化方法および生物学的利用能 |
US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
FR2954320B1 (fr) * | 2009-12-17 | 2012-06-15 | Cll Pharma | Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels |
US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
US9089484B2 (en) | 2010-03-26 | 2015-07-28 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor Xa inhibitors for oral administration |
US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
KR20140026354A (ko) | 2011-01-07 | 2014-03-05 | 메리온 리서치 Ⅲ 리미티드 | 경구 투여용 철의 제약 조성물 |
EP2694681B1 (en) | 2011-04-04 | 2017-06-07 | The Trustees of Columbia University in the City of New York | Pharmacogenetic test for anti-resorptive therapy-associated osteonecrosis of the jaw |
JP6261512B2 (ja) * | 2011-11-16 | 2018-01-17 | デューク ユニバーシティ | 心機能障害を治療及び/又は低減するためのビスホスホネート組成物並びに方法 |
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-
2010
- 2010-02-25 US US12/712,527 patent/US20100215743A1/en not_active Abandoned
- 2010-02-25 WO PCT/US2010/025305 patent/WO2010099255A1/en active Application Filing
- 2010-02-25 CA CA2751854A patent/CA2751854A1/en not_active Abandoned
- 2010-02-25 EP EP10746804A patent/EP2400851A4/en not_active Withdrawn
- 2010-02-25 AR ARP100100559A patent/AR075613A1/es unknown
- 2010-02-25 JP JP2011552140A patent/JP2012518686A/ja active Pending
- 2010-02-25 TW TW099105490A patent/TWI480286B/zh not_active IP Right Cessation
-
2015
- 2015-12-14 JP JP2015243218A patent/JP2016104759A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP2400851A1 (en) | 2012-01-04 |
EP2400851A4 (en) | 2012-09-05 |
TWI480286B (zh) | 2015-04-11 |
TW201035109A (en) | 2010-10-01 |
CA2751854A1 (en) | 2010-09-02 |
WO2010099255A1 (en) | 2010-09-02 |
JP2012518686A (ja) | 2012-08-16 |
US20100215743A1 (en) | 2010-08-26 |
JP2016104759A (ja) | 2016-06-09 |
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