AU2001240020B9 - High potency recombinant antibodies and method for producing them - Google Patents

High potency recombinant antibodies and method for producing them Download PDF

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Publication number
AU2001240020B9
AU2001240020B9 AU2001240020A AU2001240020A AU2001240020B9 AU 2001240020 B9 AU2001240020 B9 AU 2001240020B9 AU 2001240020 A AU2001240020 A AU 2001240020A AU 2001240020 A AU2001240020 A AU 2001240020A AU 2001240020 B9 AU2001240020 B9 AU 2001240020B9
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AU
Australia
Prior art keywords
antibody
cdr2
cdr3
cdrs
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001240020A
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English (en)
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AU2001240020B2 (en
AU2001240020A1 (en
Inventor
William D. Huse
Leslie S. Johnson
Scott Koenig
Jeffry D. Watkins
Herren Wu
James F. Young
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MedImmune LLC
Original Assignee
MedImmune LLC
Applied Molecular Evolution Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MedImmune LLC, Applied Molecular Evolution Inc filed Critical MedImmune LLC
Publication of AU2001240020A1 publication Critical patent/AU2001240020A1/en
Priority to AU2006203134A priority Critical patent/AU2006203134B2/en
Application granted granted Critical
Publication of AU2001240020B2 publication Critical patent/AU2001240020B2/en
Priority to AU2007202040A priority patent/AU2007202040B2/en
Assigned to MEDIMMUNE, LLC, APPLIED MOLECULAR EVOLUTION, INC. reassignment MEDIMMUNE, LLC Alteration of Name(s) in Register under S187 Assignors: APPLIED MOLECULAR EVOLUTION, INC., MEDIMMUNE, INC.
Publication of AU2001240020B9 publication Critical patent/AU2001240020B9/en
Priority to AU2010202006A priority patent/AU2010202006B2/en
Priority to AU2010219289A priority patent/AU2010219289B2/en
Assigned to MEDIMMUNE, LLC reassignment MEDIMMUNE, LLC Request for Assignment Assignors: APPLIED MOLECULAR EVOLUTION, INC., MEDIMMUNE, LLC
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001240020A 2000-01-27 2001-03-01 High potency recombinant antibodies and method for producing them Ceased AU2001240020B9 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2006203134A AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2007202040A AU2007202040B2 (en) 2000-03-01 2007-05-08 High potency recombinant antibodies and method for producing them
AU2010202006A AU2010202006B2 (en) 2000-01-27 2010-05-18 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2010219289A AU2010219289B2 (en) 2000-03-01 2010-09-03 High potency recombinant antibodies and method for producing them

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18625200P 2000-03-01 2000-03-01
US60/186,252 2000-03-01
PCT/US2001/006815 WO2001064751A2 (en) 2000-03-01 2001-03-01 High potency recombinant antibodies and method for producing them

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2006203134A Division AU2006203134B2 (en) 2000-01-27 2006-07-21 Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
AU2007202040A Division AU2007202040B2 (en) 2000-03-01 2007-05-08 High potency recombinant antibodies and method for producing them

Publications (3)

Publication Number Publication Date
AU2001240020A1 AU2001240020A1 (en) 2001-11-22
AU2001240020B2 AU2001240020B2 (en) 2007-02-08
AU2001240020B9 true AU2001240020B9 (en) 2008-12-04

Family

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Family Applications (4)

Application Number Title Priority Date Filing Date
AU2001240020A Ceased AU2001240020B9 (en) 2000-01-27 2001-03-01 High potency recombinant antibodies and method for producing them
AU4002001A Pending AU4002001A (en) 2000-03-01 2001-03-01 High potency recombinant antibodies and method for producing them
AU2007202040A Ceased AU2007202040B2 (en) 2000-03-01 2007-05-08 High potency recombinant antibodies and method for producing them
AU2010219289A Ceased AU2010219289B2 (en) 2000-03-01 2010-09-03 High potency recombinant antibodies and method for producing them

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU4002001A Pending AU4002001A (en) 2000-03-01 2001-03-01 High potency recombinant antibodies and method for producing them
AU2007202040A Ceased AU2007202040B2 (en) 2000-03-01 2007-05-08 High potency recombinant antibodies and method for producing them
AU2010219289A Ceased AU2010219289B2 (en) 2000-03-01 2010-09-03 High potency recombinant antibodies and method for producing them

Country Status (10)

Country Link
US (2) US7700735B2 (US07700735-20100420-C00007.png)
EP (3) EP2341075A1 (US07700735-20100420-C00007.png)
JP (2) JP2003525061A (US07700735-20100420-C00007.png)
AU (4) AU2001240020B9 (US07700735-20100420-C00007.png)
CA (1) CA2401652A1 (US07700735-20100420-C00007.png)
CY (1) CY1113298T1 (US07700735-20100420-C00007.png)
DK (1) DK1259547T3 (US07700735-20100420-C00007.png)
ES (1) ES2390761T3 (US07700735-20100420-C00007.png)
PT (1) PT1259547E (US07700735-20100420-C00007.png)
WO (1) WO2001064751A2 (US07700735-20100420-C00007.png)

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AU2010219289A1 (en) 2010-09-30
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WO2001064751A3 (en) 2001-12-20
PT1259547E (pt) 2012-10-15
US8153133B2 (en) 2012-04-10
DK1259547T3 (da) 2012-10-15
US7700735B2 (en) 2010-04-20
JP2003525061A (ja) 2003-08-26
EP2341075A1 (en) 2011-07-06
EP1259547A2 (en) 2002-11-27
AU4002001A (en) 2001-09-12
CA2401652A1 (en) 2001-09-07
AU2007202040A1 (en) 2007-05-24
AU2001240020B2 (en) 2007-02-08
AU2007202040B2 (en) 2010-06-10
CY1113298T1 (el) 2016-04-13
AU2010219289B2 (en) 2012-05-10
EP2341074A1 (en) 2011-07-06
EP1259547B1 (en) 2012-07-11
JP2010162025A (ja) 2010-07-29
ES2390761T3 (es) 2012-11-16

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