AU1825299A - Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents - Google Patents

Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents

Info

Publication number
AU1825299A
AU1825299A AU18252/99A AU1825299A AU1825299A AU 1825299 A AU1825299 A AU 1825299A AU 18252/99 A AU18252/99 A AU 18252/99A AU 1825299 A AU1825299 A AU 1825299A AU 1825299 A AU1825299 A AU 1825299A
Authority
AU
Australia
Prior art keywords
hydroxyl
amino
bioactive agents
containing bioactive
polymeric prodrugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU18252/99A
Other languages
English (en)
Inventor
Yun H. Choe
Richard B Greenwald
Annapurna Pendri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzon Pharmaceuticals Inc
Original Assignee
Enzon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/183,557 external-priority patent/US6180095B1/en
Application filed by Enzon Inc filed Critical Enzon Inc
Publication of AU1825299A publication Critical patent/AU1825299A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyethers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU18252/99A 1997-12-17 1998-12-14 Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents Abandoned AU1825299A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US99243597A 1997-12-17 1997-12-17
US08992435 1997-12-17
US09183557 1998-10-30
US09/183,557 US6180095B1 (en) 1997-12-17 1998-10-30 Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
PCT/US1998/026565 WO1999030727A1 (en) 1997-12-17 1998-12-14 Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents

Publications (1)

Publication Number Publication Date
AU1825299A true AU1825299A (en) 1999-07-05

Family

ID=26879271

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18252/99A Abandoned AU1825299A (en) 1997-12-17 1998-12-14 Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents

Country Status (6)

Country Link
US (1) US6720306B2 (https=)
EP (1) EP1037649B1 (https=)
JP (1) JP4465109B2 (https=)
AU (1) AU1825299A (https=)
CA (1) CA2312975C (https=)
WO (1) WO1999030727A1 (https=)

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US6720306B2 (en) 2004-04-13
JP4465109B2 (ja) 2010-05-19
WO1999030727A9 (en) 1999-09-23
CA2312975A1 (en) 1999-06-24
CA2312975C (en) 2012-08-21
EP1037649B1 (en) 2009-09-30
JP2002508400A (ja) 2002-03-19
EP1037649A1 (en) 2000-09-27
US20010031873A1 (en) 2001-10-18
WO1999030727A1 (en) 1999-06-24
EP1037649A4 (en) 2004-11-17

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