ATE96036T1 - Verfahren zum zuechten von bordetella-pertussis, ein pertussis-toxoid und ein pertussis-impfstoff. - Google Patents

Verfahren zum zuechten von bordetella-pertussis, ein pertussis-toxoid und ein pertussis-impfstoff.

Info

Publication number
ATE96036T1
ATE96036T1 AT87306165T AT87306165T ATE96036T1 AT E96036 T1 ATE96036 T1 AT E96036T1 AT 87306165 T AT87306165 T AT 87306165T AT 87306165 T AT87306165 T AT 87306165T AT E96036 T1 ATE96036 T1 AT E96036T1
Authority
AT
Austria
Prior art keywords
pertussis
vaccine
toxoid
disclosed
gelatin
Prior art date
Application number
AT87306165T
Other languages
English (en)
Inventor
Masashi Chazono
Iwao Yoshida
Takeo Konobe
Juichiro Osame
Keisuke Takaku
Original Assignee
Univ Osaka Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka Res Found filed Critical Univ Osaka Res Found
Application granted granted Critical
Publication of ATE96036T1 publication Critical patent/ATE96036T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/22—Processes using, or culture media containing, cellulose or hydrolysates thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT87306165T 1987-04-24 1987-07-13 Verfahren zum zuechten von bordetella-pertussis, ein pertussis-toxoid und ein pertussis-impfstoff. ATE96036T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10236087 1987-04-24
EP87306165A EP0287732B1 (de) 1987-04-24 1987-07-13 Verfahren zum Züchten von Bordetella-Pertussis, ein Pertussis-Toxoid und ein Pertussis-Impfstoff

Publications (1)

Publication Number Publication Date
ATE96036T1 true ATE96036T1 (de) 1993-11-15

Family

ID=14325294

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87306165T ATE96036T1 (de) 1987-04-24 1987-07-13 Verfahren zum zuechten von bordetella-pertussis, ein pertussis-toxoid und ein pertussis-impfstoff.

Country Status (10)

Country Link
US (1) US4849358A (de)
EP (1) EP0287732B1 (de)
KR (1) KR900007644B1 (de)
AT (1) ATE96036T1 (de)
CA (1) CA1337859C (de)
DE (1) DE3787887T2 (de)
DK (1) DK365287A (de)
ES (1) ES2059380T3 (de)
FI (1) FI86959C (de)
NO (1) NO172188C (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2596413B1 (fr) * 1986-03-27 1988-06-10 Merieux Inst Nouveaux milieux de culture de bacteries appartenant au genre bordetella, contenant des derives etherifies de polymeres de d-glucose, et leur application
US5101019A (en) * 1987-05-22 1992-03-31 Takeda Chemical Industries, Ltd. Method for removing pertussis endotoxin, a pertussis toxoid and its production
JP2849632B2 (ja) * 1988-04-08 1999-01-20 社団法人北里研究所 ワクチン製剤
US5000952A (en) * 1988-08-02 1991-03-19 The Board Of Trustees Of The Leland Stanford, Jr. University Polypeptide pertussis toxin vaccine
CA1341123C (en) * 1988-10-27 2000-10-17 David A. Relman Filamentous hemagglutinin of b. pertussis
JP2706792B2 (ja) * 1988-11-29 1998-01-28 財団法人化学及血清療法研究所 百日咳毒素のトキソイド化法
US5578308A (en) * 1990-02-12 1996-11-26 Capiau; Carine Glutaraldehyde and formalin detoxified bordetella toxin vaccine
US5474900A (en) * 1990-03-16 1995-12-12 Sekisui Chemical Co., Ltd. Process for preparing purified syphilis antigen from Treponema palljdum
US5718909A (en) * 1991-02-18 1998-02-17 Medscand Ab Sheet containing carbohydrate derivative for removal of E. coli
CA2075521C (en) * 1992-05-05 1995-11-28 Kuniaki Koyama Stabilized live vaccine
US6051240A (en) * 1994-04-28 2000-04-18 Takeda Chemical Industries, Ltd. Method of separating protective components of Bordetella pertussis
DE19803453A1 (de) * 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB512196A (en) * 1937-08-19 1939-08-30 Lederle Lab Inc Method of preparing pertussis toxin and toxoid
US2359388A (en) * 1941-02-13 1944-10-03 Lederle Lab Inc Method of preparing pertussis toxin and toxoid
DE2461439C3 (de) * 1974-12-24 1980-03-20 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines schützenden Antigens von Bordetella Pertussis sowie jenes enthaltendes Mittel
FR2356429A1 (fr) * 1976-06-28 1978-01-27 Bertoye Renee Procede de preparation d'endo-antigenes de bordetella pertussis et bordetella parapertussis utiles notamment au traitement de la coqueluche
DE2961293D1 (en) * 1978-02-17 1982-01-14 Nat Res Dev Immunogenic cell envelope preparations
US4247452A (en) * 1978-03-01 1981-01-27 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Purification of pertussis haemagglutinins
JPS5647167A (en) * 1979-09-26 1981-04-28 Ricoh Co Ltd Facsimile transmitter
JPS581482B2 (ja) * 1980-06-11 1983-01-11 中松 義郎 無加熱反射ライト
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
US4500639A (en) * 1981-10-15 1985-02-19 Teijin Limited Culturing Bordetella in media containing etherified cyclodextrin
US4474758A (en) * 1981-11-19 1984-10-02 American Cyanamid Company Haemophilus influenzae type b and pertussis outer membrane component combined vaccine
FR2522268A1 (fr) * 1982-02-26 1983-09-02 Green Cross Corp Vaccin anti-ourlien vivant et procede pour le stabiliser
JPS58222032A (ja) * 1982-06-18 1983-12-23 Teijin Ltd 百日咳毒素のサブユニツト蛋白
JPS59110626A (ja) * 1982-12-17 1984-06-26 Kaken Pharmaceut Co Ltd Ｂ−オリゴマ−含有百日咳ワクチンおよびその製造方法
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
JPS59175439A (ja) * 1983-03-23 1984-10-04 Teijin Ltd 繊維状赤血球凝集素の製法
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
US4551429A (en) * 1983-09-15 1985-11-05 American Home Products Corporation Stimulation of antigen production by Bordetella pertussis
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
JPS60226822A (ja) * 1984-04-25 1985-11-12 Chemo Sero Therapeut Res Inst 線維状赤血球凝集素の精製方法
JPS60218326A (ja) * 1984-04-14 1985-11-01 Chemo Sero Therapeut Res Inst 線維状赤血球凝集素の精製方法
AU571078B2 (en) * 1984-04-14 1988-03-31 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Purification of filamentous hemagglutinin
JPS60237027A (ja) * 1984-05-07 1985-11-25 Chemo Sero Therapeut Res Inst 線維状赤血球凝集素の精製方法
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
JPS6176422A (ja) * 1984-09-22 1986-04-18 Chemo Sero Therapeut Res Inst 百日ぜきコンポ−ネントワクチンおよび百日ぜき・ジフテリア・破傷風混合ワクチンの製造方法
GB8512972D0 (en) * 1985-05-22 1985-06-26 Univ Glasgow Vaccine production
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
FR2596413B1 (fr) * 1986-03-27 1988-06-10 Merieux Inst Nouveaux milieux de culture de bacteries appartenant au genre bordetella, contenant des derives etherifies de polymeres de d-glucose, et leur application
US4699786A (en) * 1986-05-09 1987-10-13 American Cyanamid Company Enhanced large scale cultivation of bordetella pertussis cells for vaccine production using lactoglobulin
US4705686A (en) * 1986-05-09 1987-11-10 American Cyanamid Process for the preparation of acellular Bordetalla pertussis vaccine
JP2537042B2 (ja) * 1986-11-27 1996-09-25 社団法人北里研究所 ボルデテラ・ブロンキセプチカ感染症生菌ワクチン用原株の製造法および生菌ワクチン
JPH0628277A (ja) * 1992-07-10 1994-02-04 Nec Software Ltd ファイル転送装置
JP3240711B2 (ja) * 1992-11-11 2001-12-25 ソニー株式会社 Ｙ／ｃ分離フィルタ装置

Also Published As

Publication number Publication date
CA1337859C (en) 1996-01-02
FI873083A0 (fi) 1987-07-13
FI873083A (fi) 1988-10-25
KR880012238A (ko) 1988-11-26
FI86959C (fi) 1992-11-10
EP0287732A1 (de) 1988-10-26
NO872919L (no) 1988-10-25
ES2059380T3 (es) 1994-11-16
EP0287732B1 (de) 1993-10-20
DK365287A (da) 1988-10-25
DE3787887D1 (de) 1993-11-25
DE3787887T2 (de) 1994-02-10
DK365287D0 (da) 1987-07-14
KR900007644B1 (ko) 1990-10-17
NO872919D0 (no) 1987-07-13
NO172188C (no) 1993-06-16
US4849358A (en) 1989-07-18
FI86959B (fi) 1992-07-31
NO172188B (no) 1993-03-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time