ATE73805T1 - Makrolid-verbindungen, ihre herstellung und ihre verwendung. - Google Patents
Makrolid-verbindungen, ihre herstellung und ihre verwendung.Info
- Publication number
- ATE73805T1 ATE73805T1 AT87310933T AT87310933T ATE73805T1 AT E73805 T1 ATE73805 T1 AT E73805T1 AT 87310933 T AT87310933 T AT 87310933T AT 87310933 T AT87310933 T AT 87310933T AT E73805 T1 ATE73805 T1 AT E73805T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- macrolide compounds
- macrolide
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/898—Streptomyces hygroscopicus
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61295452 | 1986-12-11 | ||
| EP87310933A EP0274871B1 (de) | 1986-12-11 | 1987-12-11 | Makrolid-Verbindungen, ihre Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE73805T1 true ATE73805T1 (de) | 1992-04-15 |
Family
ID=17820769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87310933T ATE73805T1 (de) | 1986-12-11 | 1987-12-11 | Makrolid-verbindungen, ihre herstellung und ihre verwendung. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5008191A (de) |
| EP (1) | EP0274871B1 (de) |
| KR (1) | KR960013079B1 (de) |
| CN (2) | CN1020114C (de) |
| AR (1) | AR243528A1 (de) |
| AT (1) | ATE73805T1 (de) |
| AU (1) | AU605218B2 (de) |
| BR (1) | BR8706745A (de) |
| CA (1) | CA1338050C (de) |
| DE (1) | DE3777604D1 (de) |
| DK (2) | DK168488B1 (de) |
| EG (1) | EG18720A (de) |
| ES (1) | ES2033325T3 (de) |
| GR (1) | GR3004882T3 (de) |
| HU (1) | HU198723B (de) |
| IL (1) | IL84801A (de) |
| NZ (1) | NZ222884A (de) |
| OA (1) | OA08698A (de) |
| PH (1) | PH26780A (de) |
| PT (1) | PT86350B (de) |
| RU (1) | RU1836426C (de) |
| SU (1) | SU1604159A3 (de) |
| ZA (1) | ZA879279B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2587241B2 (ja) * | 1986-07-24 | 1997-03-05 | ビ−チヤム・グル−プ・ピ−エルシ− | 新規化合物、その製法及びそれを含む医薬組成物 |
| US5212322A (en) * | 1986-12-11 | 1993-05-18 | Sankyo Company, Limited | Macrolide compounds, their preparation and their use |
| AR243528A1 (es) * | 1986-12-11 | 1993-08-31 | Sankyo Co | Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida. |
| EP0298423A3 (de) * | 1987-07-07 | 1989-10-25 | Kumiai Chemical Industry Co., Ltd. | KSB-1939-Antibiotikum-Derivate und Verfahren zu ihrer Herstellung sowie diese enthaltenden pestiziden Zusammensetzungen |
| NZ233680A (en) * | 1989-05-17 | 1995-02-24 | Beecham Group Plc | Avermectins and milbemycins and compositions thereof |
| IT1255135B (it) * | 1992-05-05 | 1995-10-20 | Principio attivo a base di avermectine, ceppo e procedimento per la sua preparazione e composizione veterinaria che lo contiene. | |
| US5364623A (en) * | 1993-04-30 | 1994-11-15 | Bristol-Myers Squibb Company | Antibiotic produced by Bacillus subtilis ATCC 55422 capable of inhibiting bacteria |
| US5362863A (en) * | 1993-09-29 | 1994-11-08 | Merck & Co., Inc. | Process for the preparation of 4"-amino avermectin compounds |
| MXPA01012085A (es) * | 1999-05-26 | 2002-06-04 | Novartis Ag | Derivados de milbemicina 4-sustituidos. |
| JP4373080B2 (ja) * | 2002-12-24 | 2009-11-25 | 三井化学アグロ株式会社 | ミルベマイシン類の精製法 |
| EP2886640A1 (de) | 2013-12-18 | 2015-06-24 | Riga Technical University | Trennverfahren für Milbemycin A3 und A4 |
| CN103833811A (zh) * | 2014-03-25 | 2014-06-04 | 武汉大学 | 一种阿维菌素衍生物及其制备方法 |
| CN106148215B (zh) | 2015-03-27 | 2019-06-14 | 浙江海正药业股份有限公司 | 一种链霉菌及其生产米尔贝霉素a4的方法 |
| CN106148216B (zh) * | 2015-03-27 | 2019-06-04 | 浙江海正药业股份有限公司 | 一种链霉菌及其生产米尔贝霉素a3的方法 |
| CN104860961B (zh) * | 2015-04-10 | 2017-08-04 | 新宇药业股份有限公司 | 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法 |
| CN109516996B (zh) * | 2018-11-26 | 2021-12-17 | 山东农业大学 | 一种大环内酯类衍生物、其合成及应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984564A (en) * | 1972-06-08 | 1976-10-05 | Sankyo Company Limited | Antibiotic substances B-41, their production and their use as insecticides and acaricides |
| US4429042A (en) * | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
| US4378353A (en) * | 1981-02-17 | 1983-03-29 | Merck & Co., Inc. | Novel C-076 compounds |
| US4412991A (en) * | 1981-08-28 | 1983-11-01 | Merck & Co., Inc. | 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use |
| NZ201681A (en) * | 1981-09-03 | 1985-11-08 | Merck & Co Inc | Avermectin derivatives and parasiticidal compositions |
| US4415669A (en) * | 1981-12-07 | 1983-11-15 | Merck & Co., Inc. | Substance and process for its production |
| US4582852A (en) * | 1983-11-02 | 1986-04-15 | Ciba-Geigy Corporation | 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites |
| US4547491A (en) * | 1984-07-18 | 1985-10-15 | Merck & Co., Inc. | C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use |
| HUT39739A (en) * | 1984-12-04 | 1986-10-29 | Ciba Geigy Ag | Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof |
| NZ215917A (en) * | 1985-05-02 | 1989-10-27 | Merck & Co Inc | 22-oh milbemycin derivatives and parasiticidal compositions |
| GB8606116D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
| GB8606120D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
| GB8606123D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
| JP2587241B2 (ja) * | 1986-07-24 | 1997-03-05 | ビ−チヤム・グル−プ・ピ−エルシ− | 新規化合物、その製法及びそれを含む医薬組成物 |
| AR243528A1 (es) * | 1986-12-11 | 1993-08-31 | Sankyo Co | Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida. |
| DE3889676D1 (de) * | 1987-02-04 | 1994-06-30 | Ciba Geigy | Mikrobielles Verfahren zur Herstellung von Milbemycin-Derivaten. |
| EP0298423A3 (de) * | 1987-07-07 | 1989-10-25 | Kumiai Chemical Industry Co., Ltd. | KSB-1939-Antibiotikum-Derivate und Verfahren zu ihrer Herstellung sowie diese enthaltenden pestiziden Zusammensetzungen |
| JPH01197488A (ja) * | 1988-02-02 | 1989-08-09 | Kumiai Chem Ind Co Ltd | 生理活性物質ｋｓｂ−１９３９化合物及びその製造法 |
| JPS6429378A (en) * | 1987-07-23 | 1989-01-31 | Kumiai Chemical Industry Co | Physiologically active substance and production thereof |
| JPH01272587A (ja) * | 1987-10-09 | 1989-10-31 | Microbial Chem Res Found | マクロライド抗生物質ｍｉ１９８物質及びその製造法、並びに線形動物又は節足動物の殺滅剤 |
-
1987
- 1987-11-04 AR AR87309553A patent/AR243528A1/es active
- 1987-12-10 RU SU4203955A patent/RU1836426C/ru active
- 1987-12-10 EG EG71687A patent/EG18720A/xx active
- 1987-12-10 US US07/131,413 patent/US5008191A/en not_active Expired - Lifetime
- 1987-12-10 ZA ZA879279A patent/ZA879279B/xx unknown
- 1987-12-11 IL IL84801A patent/IL84801A/xx not_active IP Right Cessation
- 1987-12-11 BR BR8706745A patent/BR8706745A/pt not_active IP Right Cessation
- 1987-12-11 PT PT86350A patent/PT86350B/pt unknown
- 1987-12-11 DE DE8787310933T patent/DE3777604D1/de not_active Expired - Fee Related
- 1987-12-11 AT AT87310933T patent/ATE73805T1/de not_active IP Right Cessation
- 1987-12-11 OA OA59240A patent/OA08698A/xx unknown
- 1987-12-11 NZ NZ222884A patent/NZ222884A/en unknown
- 1987-12-11 CN CN87108339A patent/CN1020114C/zh not_active Expired - Fee Related
- 1987-12-11 EP EP87310933A patent/EP0274871B1/de not_active Expired - Lifetime
- 1987-12-11 KR KR1019870014199A patent/KR960013079B1/ko not_active IP Right Cessation
- 1987-12-11 HU HU875602A patent/HU198723B/hu not_active IP Right Cessation
- 1987-12-11 AU AU82479/87A patent/AU605218B2/en not_active Ceased
- 1987-12-11 ES ES198787310933T patent/ES2033325T3/es not_active Expired - Lifetime
- 1987-12-11 PH PH36205A patent/PH26780A/en unknown
- 1987-12-11 CA CA000554084A patent/CA1338050C/en not_active Expired - Fee Related
- 1987-12-11 DK DK653287A patent/DK168488B1/da not_active IP Right Cessation
-
1989
- 1989-01-23 SU SU4613316A patent/SU1604159A3/ru active
-
1992
- 1992-03-27 CN CN92102223A patent/CN1028530C/zh not_active Expired - Fee Related
- 1992-06-11 GR GR920401225T patent/GR3004882T3/el unknown
-
1993
- 1993-08-04 DK DK090393A patent/DK168994B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3777604D1 (de) | 1992-04-23 |
| CN1064866A (zh) | 1992-09-30 |
| ES2033325T3 (es) | 1993-03-16 |
| DK168488B1 (da) | 1994-04-05 |
| DK168994B1 (da) | 1994-07-25 |
| DK90393D0 (da) | 1993-08-04 |
| KR880007740A (ko) | 1988-08-29 |
| EP0274871B1 (de) | 1992-03-18 |
| IL84801A (en) | 1992-02-16 |
| KR960013079B1 (ko) | 1996-09-30 |
| RU1836426C (ru) | 1993-08-23 |
| HU198723B (en) | 1989-11-28 |
| HUT45982A (en) | 1988-09-28 |
| CN1020114C (zh) | 1993-03-17 |
| NZ222884A (en) | 1992-02-25 |
| DK653287A (da) | 1988-06-12 |
| SU1604159A3 (ru) | 1990-10-30 |
| PH26780A (en) | 1992-10-13 |
| CN1028530C (zh) | 1995-05-24 |
| DK90393A (da) | 1993-08-04 |
| AR243528A1 (es) | 1993-08-31 |
| DK653287D0 (da) | 1987-12-11 |
| PT86350B (pt) | 1990-11-07 |
| EP0274871A1 (de) | 1988-07-20 |
| PT86350A (en) | 1988-01-01 |
| AU8247987A (en) | 1988-06-23 |
| IL84801A0 (en) | 1988-06-30 |
| ZA879279B (en) | 1989-08-30 |
| EG18720A (en) | 1993-12-30 |
| US5008191A (en) | 1991-04-16 |
| CA1338050C (en) | 1996-02-13 |
| AU605218B2 (en) | 1991-01-10 |
| GR3004882T3 (de) | 1993-04-28 |
| OA08698A (en) | 1989-03-31 |
| CN87108339A (zh) | 1988-07-13 |
| BR8706745A (pt) | 1988-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |