DK653287D0 - Marcrolidforbindelser og fremgangsmaade til fremstilling deraf samt deres anvendelse - Google Patents

Marcrolidforbindelser og fremgangsmaade til fremstilling deraf samt deres anvendelse

Info

Publication number
DK653287D0
DK653287D0 DK653287A DK653287A DK653287D0 DK 653287 D0 DK653287 D0 DK 653287D0 DK 653287 A DK653287 A DK 653287A DK 653287 A DK653287 A DK 653287A DK 653287 D0 DK653287 D0 DK 653287D0
Authority
DK
Denmark
Prior art keywords
marcrolid
procedures
compounds
producing
marcrolid compounds
Prior art date
Application number
DK653287A
Other languages
English (en)
Other versions
DK168488B1 (da
DK653287A (da
Inventor
Takao Okazaki
Shuji Takahashi
Seigo Iwado
Keiji Tanaka
Toshiaki Yanai
Hisaki Kajino
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK653287D0 publication Critical patent/DK653287D0/da
Publication of DK653287A publication Critical patent/DK653287A/da
Application granted granted Critical
Publication of DK168488B1 publication Critical patent/DK168488B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/898—Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Insects & Arthropods (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK653287A 1986-12-11 1987-12-11 Fremgangsmåde til fremstilling af en parasiticid macrolidforbindelse DK168488B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29545286 1986-12-11
JP61295452 1986-12-11

Publications (3)

Publication Number Publication Date
DK653287D0 true DK653287D0 (da) 1987-12-11
DK653287A DK653287A (da) 1988-06-12
DK168488B1 DK168488B1 (da) 1994-04-05

Family

ID=17820769

Family Applications (2)

Application Number Title Priority Date Filing Date
DK653287A DK168488B1 (da) 1986-12-11 1987-12-11 Fremgangsmåde til fremstilling af en parasiticid macrolidforbindelse
DK090393A DK168994B1 (da) 1986-12-11 1993-08-04 Fremgangsmåde til fremstilling af en parasiticid macrolidforbindelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK090393A DK168994B1 (da) 1986-12-11 1993-08-04 Fremgangsmåde til fremstilling af en parasiticid macrolidforbindelse

Country Status (23)

Country Link
US (1) US5008191A (da)
EP (1) EP0274871B1 (da)
KR (1) KR960013079B1 (da)
CN (2) CN1020114C (da)
AR (1) AR243528A1 (da)
AT (1) ATE73805T1 (da)
AU (1) AU605218B2 (da)
BR (1) BR8706745A (da)
CA (1) CA1338050C (da)
DE (1) DE3777604D1 (da)
DK (2) DK168488B1 (da)
EG (1) EG18720A (da)
ES (1) ES2033325T3 (da)
GR (1) GR3004882T3 (da)
HU (1) HU198723B (da)
IL (1) IL84801A (da)
NZ (1) NZ222884A (da)
OA (1) OA08698A (da)
PH (1) PH26780A (da)
PT (1) PT86350B (da)
RU (1) RU1836426C (da)
SU (1) SU1604159A3 (da)
ZA (1) ZA879279B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2587241B2 (ja) * 1986-07-24 1997-03-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
US5212322A (en) * 1986-12-11 1993-05-18 Sankyo Company, Limited Macrolide compounds, their preparation and their use
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
EP0298423A3 (en) * 1987-07-07 1989-10-25 Kumiai Chemical Industry Co., Ltd. Antibiotic ksb-1939 compounds and production process thereof as well as pesticidal agents containing same
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
IT1255135B (it) * 1992-05-05 1995-10-20 Principio attivo a base di avermectine, ceppo e procedimento per la sua preparazione e composizione veterinaria che lo contiene.
US5364623A (en) * 1993-04-30 1994-11-15 Bristol-Myers Squibb Company Antibiotic produced by Bacillus subtilis ATCC 55422 capable of inhibiting bacteria
US5362863A (en) * 1993-09-29 1994-11-08 Merck & Co., Inc. Process for the preparation of 4"-amino avermectin compounds
AU4925100A (en) * 1999-05-26 2000-12-18 Novartis Ag 4-substituted milbemycin derivatives
JP4373080B2 (ja) * 2002-12-24 2009-11-25 三井化学アグロ株式会社 ミルベマイシン類の精製法
EP2886640A1 (en) 2013-12-18 2015-06-24 Riga Technical University Process for isolation of milbemycins A3 and A4
CN103833811A (zh) * 2014-03-25 2014-06-04 武汉大学 一种阿维菌素衍生物及其制备方法
CN106148216B (zh) * 2015-03-27 2019-06-04 浙江海正药业股份有限公司 一种链霉菌及其生产米尔贝霉素a3的方法
CN106148215B (zh) 2015-03-27 2019-06-14 浙江海正药业股份有限公司 一种链霉菌及其生产米尔贝霉素a4的方法
CN104860961B (zh) * 2015-04-10 2017-08-04 新宇药业股份有限公司 一种制备5‑氧（对‑硝基苯甲酰）‑尼莫克汀的方法
CN109516996B (zh) * 2018-11-26 2021-12-17 山东农业大学 一种大环内酯类衍生物、其合成及应用
CN117568205A (zh) * 2023-10-12 2024-02-20 湖北宏中药业股份有限公司 一株米尔贝霉素高产菌株及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984564A (en) * 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US4429042A (en) * 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
US4415669A (en) * 1981-12-07 1983-11-15 Merck & Co., Inc. Substance and process for its production
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
NZ215917A (en) * 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
GB8606123D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
JP2587241B2 (ja) * 1986-07-24 1997-03-05 ビ−チヤム・グル−プ・ピ−エルシ− 新規化合物、その製法及びそれを含む医薬組成物
AR243528A1 (es) * 1986-12-11 1993-08-31 Sankyo Co Procedimiento para preparar compuestos de macrolida y un procedimiento para producir con los mismos una composicion parasiticida.
ES2053797T3 (es) * 1987-02-04 1994-08-01 Ciba Geigy Ag Procedimiento microbiano para la obtencion de derivados de milbemicina.
EP0298423A3 (en) * 1987-07-07 1989-10-25 Kumiai Chemical Industry Co., Ltd. Antibiotic ksb-1939 compounds and production process thereof as well as pesticidal agents containing same
JPH01197488A (ja) * 1988-02-02 1989-08-09 Kumiai Chem Ind Co Ltd 生理活性物質ｋｓｂ−１９３９化合物及びその製造法
JPS6429378A (en) * 1987-07-23 1989-01-31 Kumiai Chemical Industry Co Physiologically active substance and production thereof
JPH01272587A (ja) * 1987-10-09 1989-10-31 Microbial Chem Res Found マクロライド抗生物質ｍｉ１９８物質及びその製造法、並びに線形動物又は節足動物の殺滅剤

Also Published As

Publication number Publication date
ZA879279B (en) 1989-08-30
AR243528A1 (es) 1993-08-31
CN1064866A (zh) 1992-09-30
CN1020114C (zh) 1993-03-17
OA08698A (en) 1989-03-31
CN1028530C (zh) 1995-05-24
DK90393D0 (da) 1993-08-04
EP0274871A1 (en) 1988-07-20
HU198723B (en) 1989-11-28
IL84801A0 (en) 1988-06-30
ATE73805T1 (de) 1992-04-15
PT86350A (en) 1988-01-01
HUT45982A (en) 1988-09-28
BR8706745A (pt) 1988-07-19
DK168488B1 (da) 1994-04-05
RU1836426C (ru) 1993-08-23
DK90393A (da) 1993-08-04
ES2033325T3 (es) 1993-03-16
CA1338050C (en) 1996-02-13
SU1604159A3 (ru) 1990-10-30
NZ222884A (en) 1992-02-25
EP0274871B1 (en) 1992-03-18
EG18720A (en) 1993-12-30
AU605218B2 (en) 1991-01-10
IL84801A (en) 1992-02-16
PT86350B (pt) 1990-11-07
US5008191A (en) 1991-04-16
KR880007740A (ko) 1988-08-29
DK168994B1 (da) 1994-07-25
CN87108339A (zh) 1988-07-13
KR960013079B1 (ko) 1996-09-30
DE3777604D1 (de) 1992-04-23
DK653287A (da) 1988-06-12
GR3004882T3 (da) 1993-04-28
PH26780A (en) 1992-10-13
AU8247987A (en) 1988-06-23

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