ATE70271T1 - Verfahren zur herstellung einer thiazepinverbindung. - Google Patents
Verfahren zur herstellung einer thiazepinverbindung.Info
- Publication number
- ATE70271T1 ATE70271T1 AT88301891T AT88301891T ATE70271T1 AT E70271 T1 ATE70271 T1 AT E70271T1 AT 88301891 T AT88301891 T AT 88301891T AT 88301891 T AT88301891 T AT 88301891T AT E70271 T1 ATE70271 T1 AT E70271T1
- Authority
- AT
- Austria
- Prior art keywords
- thiazepin
- compound
- making
- thiazepin compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878705574A GB8705574D0 (en) | 1987-03-10 | 1987-03-10 | Preparation of thiazepine compound |
EP88301891A EP0282236B1 (de) | 1987-03-10 | 1988-03-04 | Verfahren zur Herstellung einer Thiazepin-Verbindung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE70271T1 true ATE70271T1 (de) | 1991-12-15 |
Family
ID=10613643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88301891T ATE70271T1 (de) | 1987-03-10 | 1988-03-04 | Verfahren zur herstellung einer thiazepinverbindung. |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0282236B1 (de) |
JP (1) | JPH0688991B2 (de) |
KR (1) | KR960007088B1 (de) |
AR (1) | AR245707A1 (de) |
AT (1) | ATE70271T1 (de) |
AU (1) | AU595099B2 (de) |
CA (1) | CA1337345C (de) |
DD (1) | DD271703A5 (de) |
DE (1) | DE3866735D1 (de) |
DK (1) | DK175310B1 (de) |
ES (1) | ES2037822T3 (de) |
FI (1) | FI87778C (de) |
GB (2) | GB8705574D0 (de) |
GR (1) | GR3003324T3 (de) |
HU (1) | HU202231B (de) |
IE (1) | IE61122B1 (de) |
IL (1) | IL85564A (de) |
MW (1) | MW388A1 (de) |
MY (1) | MY103221A (de) |
NO (1) | NO174421C (de) |
NZ (1) | NZ223813A (de) |
PH (1) | PH25529A (de) |
PT (1) | PT86934B (de) |
ZA (1) | ZA881350B (de) |
ZW (1) | ZW2188A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03501665A (ja) * | 1987-12-15 | 1991-04-11 | シーメンス、アクチエンゲゼルシヤフト | 高温超伝導体から成る線材又は帯の製造方法とその際用いられるカプセル |
GB9109557D0 (en) * | 1991-05-02 | 1991-06-26 | Wellcome Found | Chemical compounds |
GB9611328D0 (en) * | 1996-05-31 | 1996-08-07 | Zeneca Ltd | Pharmaceutical compositions |
GB9716161D0 (en) | 1997-08-01 | 1997-10-08 | Zeneca Ltd | Process |
GB9922271D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Formulation |
US20030216376A1 (en) * | 2002-03-20 | 2003-11-20 | Revital Lifshitz-Liron | Crystalline forms of quetiapine hemifumarate |
KR100707050B1 (ko) | 2002-11-28 | 2007-04-13 | 에스케이 주식회사 | 10H-디벤조[b,f][1,4]티아제핀-11-온의 제조방법 |
US7071331B2 (en) | 2003-02-22 | 2006-07-04 | Teva Pharmaceutical Industries Ltd. | Synthesis of quetiapine and pharmaceutically acceptable salts thereof |
US7053115B2 (en) | 2003-04-07 | 2006-05-30 | Hetero Drugs Limited | Crystalline form of dorzolamide hydrochloride |
ES2223294B2 (es) * | 2003-08-08 | 2005-10-01 | Vita Cientifica, S.L. | Procedimiento de preparacion de un compuesto farmaceuticamente activo. |
US7858777B2 (en) | 2003-09-23 | 2010-12-28 | Fermion Oy | Preparation method for quetiapine |
PL368245A1 (en) * | 2004-05-28 | 2005-12-12 | CELON PHARMA Sp.z o.o. | Method for manufacture of quetiapine |
KR101038389B1 (ko) | 2004-06-23 | 2011-06-01 | 에스케이바이오팜 주식회사 | 11-(4-[2-(2-히드록시에톡시)에틸]-1-피페라지닐)-디벤조[b,f][1,4]티아제핀의 제조방법 |
WO2006056772A2 (en) * | 2004-11-23 | 2006-06-01 | Pliva Hrvatska D.O.O. | Salts of quetiapine |
GB0425729D0 (en) * | 2004-11-23 | 2004-12-22 | Pliva Res & Dev Ltd | Heterocyclic compounds |
EP1841751A1 (de) | 2005-01-24 | 2007-10-10 | IPCA Laboratories Limited | Grosstechnische herstellung von 11-[4-{2-(2-hydroxyethoxy)ethyl}-1-piperazinyl]dibenzo[b,f]-[1,4]thiazepin |
ES2234447B1 (es) * | 2005-03-07 | 2006-03-01 | Union Quimico-Farmaceutica S.A. | Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina. |
WO2006113425A1 (en) | 2005-04-14 | 2006-10-26 | Teva Pharmaceutical Industries Ltd. | Process for preparing quetiapine fumarate |
WO2006135544A1 (en) * | 2005-06-10 | 2006-12-21 | Cambrex Charles City, Inc. | SYNTHESIS OF 11-(4[-(2-HYDROXYETHOXY)ETHYL]-PIPERAZINYL)-DIBENZO[b,f][1,4]THIAZEPINE AND ITS FUMARATE SALT |
WO2007004234A1 (en) * | 2005-07-04 | 2007-01-11 | Usv Limited | A PROCESS FOR THE PREPARATION OF 2-[2-(4-DIBENZO[b,f] [L,4] THIAZEPIN-11-yl-1- PIPERAZINYL)ETHOXY] ETHANOL FUMARATE |
GB0516603D0 (en) * | 2005-08-12 | 2005-09-21 | Sandoz Ag | Processes for the preparation of organic compounds useful as serotonin receptor antagonists |
EP1948628A1 (de) | 2005-10-28 | 2008-07-30 | Fermion Oy | Aufreinigung von quetiapinhemifumarat durch kristallisation |
US20080287418A1 (en) | 2007-05-16 | 2008-11-20 | Astrazeneca Ab | Extended Release Compositions and Methods for Their Manufacture |
CN101925587B (zh) | 2008-01-31 | 2013-05-01 | 费米有限公司 | 喹硫平的制备方法 |
PT2307389E (pt) | 2008-06-20 | 2013-03-28 | Astrazeneca Ab | Derivados de dibenzotiazepina e sua utilização |
DE202009018024U1 (de) | 2008-08-01 | 2010-12-09 | Krka Tovarna Zdravil, D.D., Novo Mesto | Quetiapin-Zusammensetzung |
EP2153834A3 (de) | 2008-08-07 | 2010-02-24 | Farmaprojects, S.A. | Pharmazeutische Zusammensetzungen mit anhaltender Freisetzung, die Quetiapinsalze umfassen |
CN101676275B (zh) * | 2008-09-17 | 2014-05-07 | 北京德众万全药物技术开发有限公司 | 一种富马酸喹硫平的制备方法 |
WO2010089259A2 (en) | 2009-02-04 | 2010-08-12 | Woerwag R&D Gmbh | Sustained release composition containing quetiapine |
US20120071649A1 (en) | 2009-03-04 | 2012-03-22 | Ranbaxy Laboratories Limited | Process for the preparation of quetiapine fumarate |
WO2011121602A1 (en) | 2010-03-29 | 2011-10-06 | Hikal Limited | Process for preparation of dibenzothiazepinone compounds |
TR201008261A1 (tr) | 2010-10-08 | 2012-04-24 | Sanovel İlaç San. Ve Ti̇c. A.Ş. | Kontrollü salım gerçekleştiren ketiapin formülasyonları |
EP2848244A1 (de) | 2013-09-16 | 2015-03-18 | Yildiz Özsoy Erginer | Tablettenformulierungen mit verzögerter Freisetzung aus Quetiapin |
CN103524455A (zh) * | 2013-10-30 | 2014-01-22 | 苏州敬业医药化工有限公司 | 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法 |
CN104447615A (zh) * | 2014-02-28 | 2015-03-25 | 广东东阳光药业有限公司 | 喹硫平中间体的制备方法 |
CN104016945B (zh) * | 2014-05-27 | 2016-06-29 | 渭南畅通药化科技有限公司 | 一种半富马酸喹硫平的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE792426A (fr) * | 1971-12-09 | 1973-06-07 | Wander Ag Dr A | Nouveaux derives de la dibenzo(b,f)(1,4)thiazepine, leur preparation etleur application comme medicaments |
JPS60155171A (ja) * | 1983-12-10 | 1985-08-15 | Wako Pure Chem Ind Ltd | ポリメトキシベンジルピペラジン誘導体 |
GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
-
1987
- 1987-03-10 GB GB878705574A patent/GB8705574D0/en active Pending
-
1988
- 1988-02-22 GB GB888804063A patent/GB8804063D0/en active Pending
- 1988-02-24 IE IE50788A patent/IE61122B1/en not_active IP Right Cessation
- 1988-02-25 CA CA000559825A patent/CA1337345C/en not_active Expired - Lifetime
- 1988-02-25 ZA ZA881350A patent/ZA881350B/xx unknown
- 1988-02-26 IL IL85564A patent/IL85564A/xx not_active IP Right Cessation
- 1988-02-26 MY MYPI88000197A patent/MY103221A/en unknown
- 1988-02-29 ZW ZW21/88A patent/ZW2188A1/xx unknown
- 1988-02-29 AU AU12378/88A patent/AU595099B2/en not_active Ceased
- 1988-03-01 MW MW3/88A patent/MW388A1/xx unknown
- 1988-03-02 DK DK198801130A patent/DK175310B1/da not_active IP Right Cessation
- 1988-03-04 ES ES198888301891T patent/ES2037822T3/es not_active Expired - Lifetime
- 1988-03-04 DE DE8888301891T patent/DE3866735D1/de not_active Expired - Lifetime
- 1988-03-04 AT AT88301891T patent/ATE70271T1/de not_active IP Right Cessation
- 1988-03-04 EP EP88301891A patent/EP0282236B1/de not_active Expired - Lifetime
- 1988-03-07 HU HU881086A patent/HU202231B/hu unknown
- 1988-03-07 PH PH36600A patent/PH25529A/en unknown
- 1988-03-08 DD DD88313500A patent/DD271703A5/de unknown
- 1988-03-09 NO NO881044A patent/NO174421C/no not_active IP Right Cessation
- 1988-03-09 NZ NZ223813A patent/NZ223813A/en unknown
- 1988-03-09 FI FI881087A patent/FI87778C/fi not_active IP Right Cessation
- 1988-03-09 AR AR88310264A patent/AR245707A1/es active
- 1988-03-09 PT PT86934A patent/PT86934B/pt not_active IP Right Cessation
- 1988-03-10 KR KR1019880002483A patent/KR960007088B1/ko not_active IP Right Cessation
- 1988-03-10 JP JP63055092A patent/JPH0688991B2/ja not_active Expired - Lifetime
-
1991
- 1991-12-12 GR GR91400630T patent/GR3003324T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EELA | Cancelled due to lapse of time |