ATE5885T1 - Maytansinoide, ihre herstellung und verwendung. - Google Patents

Maytansinoide, ihre herstellung und verwendung.

Info

Publication number
ATE5885T1
ATE5885T1 AT80103138T AT80103138T ATE5885T1 AT E5885 T1 ATE5885 T1 AT E5885T1 AT 80103138 T AT80103138 T AT 80103138T AT 80103138 T AT80103138 T AT 80103138T AT E5885 T1 ATE5885 T1 AT E5885T1
Authority
AT
Austria
Prior art keywords
4alkyl
maytansinoids
preparation
15alkyl
antimitotic
Prior art date
Application number
AT80103138T
Other languages
English (en)
Inventor
Osamu Miyashita
Hiroshi Hamakoshien-Jutaku 3- Akimoto
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Application granted granted Critical
Publication of ATE5885T1 publication Critical patent/ATE5885T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT80103138T 1979-06-08 1980-06-06 Maytansinoide, ihre herstellung und verwendung. ATE5885T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7281179A JPS55164685A (en) 1979-06-08 1979-06-08 Novel maytansinoid compound and its preparation
EP80103138A EP0021178B1 (de) 1979-06-08 1980-06-06 Maytansinoide, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE5885T1 true ATE5885T1 (de) 1984-02-15

Family

ID=13500153

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80103138T ATE5885T1 (de) 1979-06-08 1980-06-06 Maytansinoide, ihre herstellung und verwendung.

Country Status (6)

Country Link
US (1) US4317821A (de)
EP (1) EP0021178B1 (de)
JP (1) JPS55164685A (de)
AT (1) ATE5885T1 (de)
CA (1) CA1135260A (de)
DE (1) DE3066149D1 (de)

Families Citing this family (289)

* Cited by examiner, † Cited by third party
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