ATE13429T1 - Neue benzofuran-derivate, ihre herstellung und verwendung. - Google Patents

Neue benzofuran-derivate, ihre herstellung und verwendung.

Info

Publication number
ATE13429T1
ATE13429T1 AT82101418T AT82101418T ATE13429T1 AT E13429 T1 ATE13429 T1 AT E13429T1 AT 82101418 T AT82101418 T AT 82101418T AT 82101418 T AT82101418 T AT 82101418T AT E13429 T1 ATE13429 T1 AT E13429T1
Authority
AT
Austria
Prior art keywords
preparation
benzofuran derivatives
new benzofuran
hydrogen
new
Prior art date
Application number
AT82101418T
Other languages
English (en)
Inventor
Eberhard Dr Schroeder
Manfred Lehmann
Clemens Dr Rufer
Irmgard Dr Boettcher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of ATE13429T1 publication Critical patent/ATE13429T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/38—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
AT82101418T 1981-03-11 1982-02-25 Neue benzofuran-derivate, ihre herstellung und verwendung. ATE13429T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813110009 DE3110009A1 (de) 1981-03-11 1981-03-11 Neue benzofuran-derivate, ihre herstellung und verwendung
EP82101418A EP0059884B1 (de) 1981-03-11 1982-02-25 Neue Benzofuran-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE13429T1 true ATE13429T1 (de) 1985-06-15

Family

ID=6127358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82101418T ATE13429T1 (de) 1981-03-11 1982-02-25 Neue benzofuran-derivate, ihre herstellung und verwendung.

Country Status (5)

Country Link
US (1) US4411910A (de)
EP (1) EP0059884B1 (de)
JP (1) JPS57203079A (de)
AT (1) ATE13429T1 (de)
DE (2) DE3110009A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8705871A1 (es) * 1984-12-29 1987-05-16 Kaken Pharma Co Ltd Un procedimiento para preparar un derivado de benzofurano
JP2514945B2 (ja) * 1987-02-05 1996-07-10 三井石油化学工業株式会社 芳香族アミン誘導体
US4911754A (en) * 1987-07-16 1990-03-27 American Cyanamid Company Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
US5409944A (en) * 1993-03-12 1995-04-25 Merck Frosst Canada, Inc. Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
US5968958A (en) * 1995-01-31 1999-10-19 Merck Frosst Canada, Inc. 5-Methanesulfonamido-3H-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2
ES2138902B1 (es) * 1997-05-19 2000-09-16 Salvat Lab Sa "5-ariltio-6-sulfonamido-3(2h)-benzofuranonas como inhibidores de la cox-2".
US7192939B2 (en) * 2002-01-30 2007-03-20 Montana State University Pestalotiopsis microsporia isolates and compounds derived therefrom
WO2008089459A1 (en) * 2007-01-19 2008-07-24 Ardea Biosciences, Inc. Inhibitors of mek
CN102807515A (zh) * 2012-09-04 2012-12-05 江苏昊华精细化工有限公司 3-甲磺酰胺基-4-苯氧基-6-（n-甲酰）胺基乙酰基苯酚的合成方法
KR102263900B1 (ko) * 2016-03-16 2021-06-14 골든 오메가 노르웨이 에이에스 오메가-3 지방산 유도체를 포함하는 분말 및 정제 및 이의 제조 방법
CN106986797B (zh) * 2017-04-24 2018-09-28 常州佳德医药科技有限公司 N-(2-(4-乙酰苯氧基)-5-甲氧基苯基)甲磺酰胺及其制备方法
CN113968838B (zh) 2020-07-25 2024-04-02 华创合成制药股份有限公司 一种硫代苯并吡喃类化合物及其在类风湿性关节炎治疗中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794081A (fr) * 1972-01-27 1973-05-16 Cortial Nouveaux produits de reaction entre une amine primaire et un aldehyde
FR2183536B1 (de) * 1972-05-09 1975-06-20 Bottu
FR2415461A1 (fr) * 1978-01-27 1979-08-24 Poupelin Jean Pierre Nouveaux medicaments a action anti-inflammatoire, antipyretique et antalgique comprenant des derives de 1-hydroxy-3 phtalide comme constituants actifs et leur procede de preparation
US4367238A (en) * 1980-01-28 1983-01-04 Fujisawa Pharmaceutical Company, Ltd. Phenyl-alkanoic acid derivative and preparation thereof

Also Published As

Publication number Publication date
EP0059884B1 (de) 1985-05-22
US4411910A (en) 1983-10-25
JPS57203079A (en) 1982-12-13
JPH038350B2 (de) 1991-02-05
DE3263710D1 (en) 1985-06-27
DE3110009A1 (de) 1982-09-30
EP0059884A1 (de) 1982-09-15

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