ATE547121T1 - Flüssigformulierung für wachstumshormone - Google Patents

Flüssigformulierung für wachstumshormone

Info

Publication number
ATE547121T1
ATE547121T1 AT05774044T AT05774044T ATE547121T1 AT E547121 T1 ATE547121 T1 AT E547121T1 AT 05774044 T AT05774044 T AT 05774044T AT 05774044 T AT05774044 T AT 05774044T AT E547121 T1 ATE547121 T1 AT E547121T1
Authority
AT
Austria
Prior art keywords
growth hormone
liquid formulation
metal salt
alkaline earth
earth metal
Prior art date
Application number
AT05774044T
Other languages
English (en)
Inventor
Tudor Arvinte
Kleiber Karine Luet
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of ATE547121T1 publication Critical patent/ATE547121T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
AT05774044T 2004-04-07 2005-03-30 Flüssigformulierung für wachstumshormone ATE547121T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04101444 2004-04-07
PCT/EP2005/051448 WO2005105148A2 (en) 2004-04-07 2005-03-30 Liquid growth hormone formulation

Publications (1)

Publication Number Publication Date
ATE547121T1 true ATE547121T1 (de) 2012-03-15

Family

ID=34928942

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05774044T ATE547121T1 (de) 2004-04-07 2005-03-30 Flüssigformulierung für wachstumshormone

Country Status (24)

Country Link
US (1) US7662393B2 (de)
EP (1) EP1740213B9 (de)
JP (1) JP4991522B2 (de)
KR (1) KR101120879B1 (de)
CN (1) CN100574801C (de)
AT (1) ATE547121T1 (de)
AU (1) AU2005237775B2 (de)
BR (1) BRPI0508798A (de)
CA (1) CA2559918A1 (de)
CY (1) CY1113834T1 (de)
DK (1) DK1740213T3 (de)
EA (1) EA010626B1 (de)
ES (1) ES2383994T3 (de)
HK (1) HK1098708A1 (de)
HR (1) HRP20120235T1 (de)
IL (1) IL178416A (de)
MX (1) MXPA06011029A (de)
NO (1) NO337249B1 (de)
PL (1) PL1740213T3 (de)
PT (1) PT1740213E (de)
RS (1) RS52310B (de)
SI (1) SI1740213T1 (de)
UA (1) UA89781C2 (de)
WO (1) WO2005105148A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1174457B1 (de) * 1999-12-03 2004-12-22 Toray Industries, Inc. Biaxial gestreckte polyesterfolie zur formgebung
KR20090130044A (ko) * 2007-04-04 2009-12-17 쎄러테크놀로지스 인코포레이티드 Ｇｈｒｈ 분자의 약제 제형
AU2011208620B2 (en) 2010-01-22 2015-04-16 Novo Nordisk Health Care Ag Stable growth hormone compounds
BR112012018116B1 (pt) 2010-01-22 2022-06-21 Novo Nordisk Health Care Ag Conjugados de hormônio do crescimento com eficácia in vivo prolongada
EP2417982A1 (de) * 2010-07-30 2012-02-15 Ferring B.V. Stabilisierung von Gonadotropinen
BR112014001921B1 (pt) * 2011-07-25 2022-05-10 Sandoz Ag Formulação aquosa farmaceuticamente aceitável, método para aumentar a estabilidade de uma formulação aquosa farmaceuticamente aceitável e embalagem principal
US8871713B2 (en) * 2013-03-01 2014-10-28 Theratechnologies Inc. Formulations of growth hormone releasing factor (GRF) molecules with improved stability
WO2014166836A1 (en) 2013-04-05 2014-10-16 Novo Nordisk A/S Growth hormone compound formulation
JP2017165713A (ja) * 2016-03-14 2017-09-21 Ｊｃｒファーマ株式会社 血清アルブミン−２０ｋ成長ホルモン融合タンパク質
US20200237652A1 (en) * 2017-08-08 2020-07-30 Csl Behring Ag Hemopexin formulations
WO2024026224A1 (en) 2022-07-29 2024-02-01 University Of Rochester Methods for improving muscle mass, strength, or function with a combination of testosterone and growth hormone

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3325223A1 (de) 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
JPS60123426A (ja) * 1983-12-07 1985-07-02 Eisai Co Ltd 経鼻投与用セクレチン製剤
JPH0720861B2 (ja) * 1984-04-09 1995-03-08 ザ デュポン マーク ファーマソウテイカル カンパニー 心臓障害の処置または予防用の医薬組成物および方法
IL79552A0 (en) * 1985-07-30 1986-10-31 Int Minerals & Chem Corp Stabilization of growth promoting hormones
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
EP0652766B2 (de) 1992-07-31 2008-03-19 Genentech, Inc. Wässrige arzneizusammensetzung, welche das menschliche wachstumshormon enthält
JPH0892125A (ja) * 1994-09-21 1996-04-09 Nippon Chem Res Kk 水性医薬組成物
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
US20020077461A1 (en) * 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
US6759393B1 (en) * 1999-04-12 2004-07-06 Pfizer Inc. Growth hormone and growth hormone releasing hormone compositions
CN1360506A (zh) * 1999-07-12 2002-07-24 格兰迪斯生物技术有限公司 生长激素配方
CA2418960A1 (en) * 2000-08-07 2002-02-14 Inhale Therapeutic Systems, Inc. Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
BR0206469A (pt) * 2001-11-14 2004-01-13 Alza Corp Composição injetável para depósito
CN1665540A (zh) * 2002-07-09 2005-09-07 桑多斯股份公司 含1,2－丙二醇的高浓度人生长激素液体制剂
US20060252682A1 (en) * 2003-03-18 2006-11-09 Ares Trading S.A. Liquid growth hormone formulation and process of preparation thereof

Also Published As

Publication number Publication date
AU2005237775B2 (en) 2010-03-04
CN1946427A (zh) 2007-04-11
NO20065097L (no) 2007-01-02
CN100574801C (zh) 2009-12-30
RS52310B (en) 2012-12-31
JP4991522B2 (ja) 2012-08-01
PT1740213E (pt) 2012-03-21
EP1740213A2 (de) 2007-01-10
DK1740213T3 (da) 2012-04-10
ES2383994T3 (es) 2012-06-28
CY1113834T1 (el) 2016-07-27
MXPA06011029A (es) 2007-01-25
PL1740213T3 (pl) 2012-08-31
EA010626B1 (ru) 2008-10-30
WO2005105148A8 (en) 2005-12-08
IL178416A (en) 2012-12-31
US7662393B2 (en) 2010-02-16
WO2005105148A2 (en) 2005-11-10
HRP20120235T1 (hr) 2012-04-30
EP1740213B1 (de) 2012-02-29
KR101120879B1 (ko) 2012-02-27
AU2005237775A1 (en) 2005-11-10
KR20070005628A (ko) 2007-01-10
WO2005105148A3 (en) 2006-07-20
EA200601874A1 (ru) 2007-02-27
BRPI0508798A (pt) 2007-09-04
SI1740213T1 (sl) 2012-04-30
JP2007532515A (ja) 2007-11-15
EP1740213B9 (de) 2012-06-13
US20080038292A1 (en) 2008-02-14
HK1098708A1 (en) 2007-07-27
UA89781C2 (uk) 2010-03-10
NO337249B1 (no) 2016-02-22
CA2559918A1 (en) 2005-11-10
IL178416A0 (en) 2007-02-11

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