NO20065097L - Flytende veksthormonformulering - Google Patents

Flytende veksthormonformulering

Info

Publication number
NO20065097L
NO20065097L NO20065097A NO20065097A NO20065097L NO 20065097 L NO20065097 L NO 20065097L NO 20065097 A NO20065097 A NO 20065097A NO 20065097 A NO20065097 A NO 20065097A NO 20065097 L NO20065097 L NO 20065097L
Authority
NO
Norway
Prior art keywords
growth hormone
metal salt
liquid growth
hormone formulation
alkaline earth
Prior art date
Application number
NO20065097A
Other languages
English (en)
Other versions
NO337249B1 (no
Inventor
Karine Luet Kleiber
Tudor Arvinte
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of NO20065097L publication Critical patent/NO20065097L/no
Publication of NO337249B1 publication Critical patent/NO337249B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Foreliggende oppfinnelse gjelder en flytende formulering som omfatter et veksthormon eller en forbindelse som stimulerer frigjøring eller forsterker aktiviteten av endocent hGH, en polyetylenpolypropylenglykol, en citrat/fosfatbuffer, et alkalimetallsalt og et alkalisk jordmetallsalt eller et pseudoalkalisk jordmetallsalt, samt en fremgangsmåte for fremstilling derav.
NO20065097A 2004-04-07 2006-11-06 Flytende veksthormonformulering NO337249B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04101444 2004-04-07
PCT/EP2005/051448 WO2005105148A2 (en) 2004-04-07 2005-03-30 Liquid growth hormone formulation

Publications (2)

Publication Number Publication Date
NO20065097L true NO20065097L (no) 2007-01-02
NO337249B1 NO337249B1 (no) 2016-02-22

Family

ID=34928942

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065097A NO337249B1 (no) 2004-04-07 2006-11-06 Flytende veksthormonformulering

Country Status (24)

Country Link
US (1) US7662393B2 (no)
EP (1) EP1740213B9 (no)
JP (1) JP4991522B2 (no)
KR (1) KR101120879B1 (no)
CN (1) CN100574801C (no)
AT (1) ATE547121T1 (no)
AU (1) AU2005237775B2 (no)
BR (1) BRPI0508798A (no)
CA (1) CA2559918A1 (no)
CY (1) CY1113834T1 (no)
DK (1) DK1740213T3 (no)
EA (1) EA010626B1 (no)
ES (1) ES2383994T3 (no)
HK (1) HK1098708A1 (no)
HR (1) HRP20120235T1 (no)
IL (1) IL178416A (no)
MX (1) MXPA06011029A (no)
NO (1) NO337249B1 (no)
PL (1) PL1740213T3 (no)
PT (1) PT1740213E (no)
RS (1) RS52310B (no)
SI (1) SI1740213T1 (no)
UA (1) UA89781C2 (no)
WO (1) WO2005105148A2 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60016911T2 (de) * 1999-12-03 2005-12-08 Toray Industries, Inc. Biaxial gestreckte polyesterfolie zur formgebung
WO2008122118A1 (en) * 2007-04-04 2008-10-16 Theratechnologies Inc. Pharmaceutical formulations of ghrh molecules
AU2011208625C1 (en) 2010-01-22 2022-08-18 Novo Nordisk Health Care Ag Growth hormones with prolonged in-vivo efficacy
RU2012134974A (ru) 2010-01-22 2014-02-27 Ново Нордиск Хелс Кеа Аг Стабилизированное соединение гормона роста
EP2417982A1 (en) * 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
BR112014001921B1 (pt) 2011-07-25 2022-05-10 Sandoz Ag Formulação aquosa farmaceuticamente aceitável, método para aumentar a estabilidade de uma formulação aquosa farmaceuticamente aceitável e embalagem principal
US8871713B2 (en) * 2013-03-01 2014-10-28 Theratechnologies Inc. Formulations of growth hormone releasing factor (GRF) molecules with improved stability
CN105120887A (zh) 2013-04-05 2015-12-02 诺和诺德保健股份有限公司 生长激素化合物制剂
WO2017159540A1 (ja) * 2016-03-14 2017-09-21 Ｊｃｒファーマ株式会社 血清アルブミン－２０ｋ成長ホルモン融合タンパク質
AU2018314767B2 (en) * 2017-08-08 2024-03-21 Csl Behring Ag Hemopexin formulations
WO2024026224A1 (en) 2022-07-29 2024-02-01 University Of Rochester Methods for improving muscle mass, strength, or function with a combination of testosterone and growth hormone

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3325223A1 (de) 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
JPS60123426A (ja) * 1983-12-07 1985-07-02 Eisai Co Ltd 経鼻投与用セクレチン製剤
AU575153B2 (en) * 1984-04-09 1988-07-21 Du Pont Merck Pharmaceutical Company, The Pharmaceutical compositions and method for treatment for prophylaxis of cardiac disorders
AU6073386A (en) 1985-07-30 1987-02-05 International Minerals & Chemical Corporation Stabilization of growth promoting hormones
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
SE9201073D0 (sv) 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
NZ255158A (en) * 1992-07-31 1997-09-22 Genentech Inc Human growth hormone; stable pharmaceutically acceptable aqueous formulation and means for preparing and storing it
JPH0892125A (ja) * 1994-09-21 1996-04-09 Nippon Chem Res Kk 水性医薬組成物
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
US20020077461A1 (en) * 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
US6759393B1 (en) * 1999-04-12 2004-07-06 Pfizer Inc. Growth hormone and growth hormone releasing hormone compositions
ATE386501T1 (de) * 1999-07-12 2008-03-15 Sandoz Ag Formulierungen von wachstumshormonen
AU8111301A (en) * 2000-08-07 2002-02-18 Inhale Therapeutic Syst Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
WO2003041685A1 (en) * 2001-11-14 2003-05-22 Alza Corporation Injectable depot composition
MXPA05000413A (es) * 2002-07-09 2005-07-22 Sandoz Ag Formulaciones liquidas con una alta concentracion de hormona de crecimiento humana (hgh) que comprenden 1,2-propilenglicol.
JP4949828B2 (ja) * 2003-03-18 2012-06-13 アレス トレーディング ソシエテ アノニム 溶液中での成長ホルモンの安定化

Also Published As

Publication number Publication date
US20080038292A1 (en) 2008-02-14
EA200601874A1 (ru) 2007-02-27
BRPI0508798A (pt) 2007-09-04
MXPA06011029A (es) 2007-01-25
CN1946427A (zh) 2007-04-11
IL178416A (en) 2012-12-31
CY1113834T1 (el) 2016-07-27
NO337249B1 (no) 2016-02-22
PT1740213E (pt) 2012-03-21
EA010626B1 (ru) 2008-10-30
WO2005105148A8 (en) 2005-12-08
UA89781C2 (uk) 2010-03-10
EP1740213B9 (en) 2012-06-13
JP2007532515A (ja) 2007-11-15
EP1740213A2 (en) 2007-01-10
KR101120879B1 (ko) 2012-02-27
AU2005237775B2 (en) 2010-03-04
ES2383994T3 (es) 2012-06-28
HK1098708A1 (en) 2007-07-27
RS52310B (en) 2012-12-31
IL178416A0 (en) 2007-02-11
WO2005105148A2 (en) 2005-11-10
DK1740213T3 (da) 2012-04-10
JP4991522B2 (ja) 2012-08-01
CN100574801C (zh) 2009-12-30
SI1740213T1 (sl) 2012-04-30
US7662393B2 (en) 2010-02-16
HRP20120235T1 (hr) 2012-04-30
ATE547121T1 (de) 2012-03-15
PL1740213T3 (pl) 2012-08-31
KR20070005628A (ko) 2007-01-10
EP1740213B1 (en) 2012-02-29
CA2559918A1 (en) 2005-11-10
WO2005105148A3 (en) 2006-07-20
AU2005237775A1 (en) 2005-11-10

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