ATE541564T1 - Schnell zerfallende tablette mit einem säurelabilen wirkstoff - Google Patents

Schnell zerfallende tablette mit einem säurelabilen wirkstoff

Info

Publication number
ATE541564T1
ATE541564T1 AT01999360T AT01999360T ATE541564T1 AT E541564 T1 ATE541564 T1 AT E541564T1 AT 01999360 T AT01999360 T AT 01999360T AT 01999360 T AT01999360 T AT 01999360T AT E541564 T1 ATE541564 T1 AT E541564T1
Authority
AT
Austria
Prior art keywords
active ingredient
tablet
acid
acid label
label active
Prior art date
Application number
AT01999360T
Other languages
German (de)
English (en)
Inventor
Rango Dietrich
Rudolf Linder
Hartmut Ney
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE541564T1 publication Critical patent/ATE541564T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AT01999360T 2000-12-07 2001-12-06 Schnell zerfallende tablette mit einem säurelabilen wirkstoff ATE541564T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00126807 2000-12-07
PCT/EP2001/014340 WO2002045694A1 (en) 2000-12-07 2001-12-06 Rapidly disintegrating tablet comprising an acid-labile active ingredient

Publications (1)

Publication Number Publication Date
ATE541564T1 true ATE541564T1 (de) 2012-02-15

Family

ID=8170591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01999360T ATE541564T1 (de) 2000-12-07 2001-12-06 Schnell zerfallende tablette mit einem säurelabilen wirkstoff

Country Status (15)

Country Link
US (1) US7147869B2 (https=)
EP (1) EP1341528B1 (https=)
JP (1) JP2004514737A (https=)
KR (1) KR20030072555A (https=)
CN (1) CN100335040C (https=)
AT (1) ATE541564T1 (https=)
AU (1) AU2002221939A1 (https=)
BR (1) BR0115986A (https=)
CA (1) CA2430829C (https=)
CY (1) CY1112615T1 (https=)
DK (1) DK1341528T3 (https=)
ES (1) ES2380654T3 (https=)
PT (1) PT1341528E (https=)
SI (1) SI1341528T1 (https=)
WO (1) WO2002045694A1 (https=)

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UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CN100536844C (zh) * 2000-12-07 2009-09-09 尼科梅德有限责任公司 包含酸不稳定活性成分的糊剂形式的药物制剂
BR0211117A (pt) * 2001-07-16 2004-06-22 Astrazeneca Ab Tablete multiparticulado, processo para a manufatura e uso do mesmo, e, método e tratamento de distúrbios gastrointestinais
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
PE20050150A1 (es) 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
CL2004000983A1 (es) 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
US8461187B2 (en) * 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US8057820B2 (en) * 2004-10-08 2011-11-15 Mcneil-Ppc, Inc. Enteric coated aspirin granules comingled with binder
US8758814B2 (en) 2004-10-08 2014-06-24 Mcneil-Ppc, Inc. Chewable enteric coated aspirin tablets
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
FR2885526B1 (fr) * 2005-05-13 2007-07-27 Flamel Technologies Sa Medicament oral a base d'inhibiteur de pompe a protons
CN100431526C (zh) * 2005-11-07 2008-11-12 上海艾力斯医药科技有限公司 一种酸敏感型药物的快速崩解片剂
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8425935B2 (en) * 2005-12-21 2013-04-23 Basf Se Pharmaceutical formulation for producing rapidly disintegrating tablets
CN102083410B (zh) * 2007-06-06 2013-04-17 巴斯夫欧洲公司 用于制备迅速崩解的片剂的药物制剂
KR20160083132A (ko) * 2007-06-06 2016-07-11 바스프 에스이 급속 붕해 정제의 제조를 위한 제약 제제
SG185296A1 (en) * 2007-10-12 2012-11-29 Takeda Pharmaceuticals Usa Inc Methods of treating gastrointestinal disorders independent of the intake of food
DE102010011421A1 (de) * 2009-03-19 2010-09-30 Schaeffler Technologies Gmbh & Co. Kg Schaltbarer Schlepphebel eines Ventiltriebs einer Brennkraftmaschine
WO2010122583A2 (en) 2009-04-24 2010-10-28 Rubicon Research Private Limited Oral pharmaceutical compositions of acid labile substances
US20110097401A1 (en) 2009-06-12 2011-04-28 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
WO2011112771A1 (en) * 2010-03-11 2011-09-15 Rich Vitamins Llc Quick dissolve nutritional powder
EP2441446A1 (en) * 2010-10-14 2012-04-18 Deva Holding Anonim Sirketi Using of superdisintegrants in cetyl myristate and/or cetyl palmitate formulations
EP2589378A1 (en) * 2010-10-14 2013-05-08 Deva Holding Anonim Sirketi Coating of cetyl myristate and/or cetyl palmitate particles
CN103429228B (zh) 2011-01-05 2016-10-26 赫士睿股份有限公司 万古霉素的喷雾干燥
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN120585773B (zh) * 2025-08-06 2025-11-07 广州仁恒医药科技股份有限公司 一种盐酸米诺环素胶囊及其制备方法

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DK2263660T3 (en) * 1998-05-18 2018-01-02 Takeda Pharmaceuticals Co Orally disintegrating tablets.
ATE291418T1 (de) * 1998-07-28 2005-04-15 Takeda Pharmaceutical Leicht zerfallende feste zubereitung
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Also Published As

Publication number Publication date
PT1341528E (pt) 2012-03-20
EP1341528A1 (en) 2003-09-10
US20040110661A1 (en) 2004-06-10
KR20030072555A (ko) 2003-09-15
BR0115986A (pt) 2003-12-23
US7147869B2 (en) 2006-12-12
SI1341528T1 (sl) 2012-05-31
CA2430829A1 (en) 2002-06-13
DK1341528T3 (da) 2012-03-26
CN100335040C (zh) 2007-09-05
CY1112615T1 (el) 2016-02-10
CA2430829C (en) 2010-06-22
HK1062264A1 (zh) 2004-10-29
ES2380654T3 (es) 2012-05-17
CN1479613A (zh) 2004-03-03
AU2002221939A1 (en) 2002-06-18
EP1341528B1 (en) 2012-01-18
WO2002045694A1 (en) 2002-06-13
JP2004514737A (ja) 2004-05-20

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