ATE529068T1 - Mehrschichtig beschichteter stent zur kontrollierten freisetzung von wirkstoffen und verfahren zu seiner herstellung - Google Patents

Mehrschichtig beschichteter stent zur kontrollierten freisetzung von wirkstoffen und verfahren zu seiner herstellung

Info

Publication number
ATE529068T1
ATE529068T1 AT06250226T AT06250226T ATE529068T1 AT E529068 T1 ATE529068 T1 AT E529068T1 AT 06250226 T AT06250226 T AT 06250226T AT 06250226 T AT06250226 T AT 06250226T AT E529068 T1 ATE529068 T1 AT E529068T1
Authority
AT
Austria
Prior art keywords
drug
coating layer
stent
layer formed
production
Prior art date
Application number
AT06250226T
Other languages
English (en)
Inventor
Seung Jung Park
Cheol Whan Lee
Kyung Bum Lee
Original Assignee
Kyung Bum Lee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyung Bum Lee filed Critical Kyung Bum Lee
Application granted granted Critical
Publication of ATE529068T1 publication Critical patent/ATE529068T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A61L2300/608—Coatings having two or more layers
    • A61L2300/61—Coatings having two or more layers containing two or more active agents in different layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT06250226T 2005-01-17 2006-01-17 Mehrschichtig beschichteter stent zur kontrollierten freisetzung von wirkstoffen und verfahren zu seiner herstellung ATE529068T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020050004331A KR100511618B1 (ko) 2005-01-17 2005-01-17 약물방출 조절형 다층 코팅 스텐트 및 이의 제조방법

Publications (1)

Publication Number Publication Date
ATE529068T1 true ATE529068T1 (de) 2011-11-15

Family

ID=36119622

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06250226T ATE529068T1 (de) 2005-01-17 2006-01-17 Mehrschichtig beschichteter stent zur kontrollierten freisetzung von wirkstoffen und verfahren zu seiner herstellung

Country Status (6)

Country Link
US (1) US8845716B2 (de)
EP (1) EP1681035B1 (de)
JP (1) JP4897267B2 (de)
KR (1) KR100511618B1 (de)
CN (1) CN1806857B (de)
AT (1) ATE529068T1 (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8784860B2 (en) * 2005-10-27 2014-07-22 Cordis Corporation Local administration of a combination of rapamycin and cilostazol for the treatment of vascular disease
US8460362B2 (en) 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
WO2008011614A2 (en) 2006-07-20 2008-01-24 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
EP3009477B1 (de) 2006-07-20 2024-01-24 Orbusneich Medical Pte. Ltd Bioresorbierbare polymerzusammensetzung für eine medizinische vorrichtung
US8900619B2 (en) * 2006-08-24 2014-12-02 Boston Scientific Scimed, Inc. Medical devices for the release of therapeutic agents
CN100431627C (zh) * 2006-08-18 2008-11-12 天津百畅医疗器械科技有限公司 可缓解缺血再灌注后自由基对细胞损伤的血管支架药物涂层
EP2073754A4 (de) 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioresorbierbare polymerzusammensetzung und hintergrund für eine medizinische vorrichtung
CN101563117B (zh) * 2006-10-20 2014-05-21 奥巴斯尼茨医学公司 具有包被层的可生物吸收的医疗设备
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
WO2008061431A1 (en) * 2006-11-20 2008-05-29 Lepu Medical Technology (Beijing) Co., Ltd. Vessel stent with multi drug-coatings
US20080172124A1 (en) * 2007-01-11 2008-07-17 Robert Lamar Bjork Multiple drug-eluting coronary artery stent for percutaneous coronary artery intervention
US8591931B2 (en) * 2007-02-14 2013-11-26 Shangdong Intech Medical Technology Co., Ltd Coronary stent with asymmetric drug releasing controlled coating
JP5461202B2 (ja) * 2007-03-09 2014-04-02 アイコン メディカル コーポレーション 医療用具用生体吸収性コーティング
US20080241215A1 (en) * 2007-03-28 2008-10-02 Robert Falotico Local vascular delivery of probucol alone or in combination with sirolimus to treat restenosis, vulnerable plaque, aaa and stroke
US20080265056A1 (en) * 2007-04-30 2008-10-30 Ke-Ming Quan Ultrasonic spray apparatus to coat a substrate
AU2008202283B2 (en) 2007-06-01 2011-01-20 Kyong-Min Shin Coating agent for drug releasing stent, preparation method thereof and drug releasing stent coated therewith
KR100904207B1 (ko) 2007-06-01 2009-06-25 (주) 태웅메디칼 스텐트용 약물 방출 코팅제, 그의 제조방법 및 이 코팅제로 코팅된 약물 방출 스텐트
KR100888219B1 (ko) 2007-06-01 2009-03-12 (주) 태웅메디칼 약물 방출 스텐트용 코팅제, 그의 제조방법 및 이 코팅제로코팅된 약물 방출 스텐트
US8048441B2 (en) * 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
KR100883329B1 (ko) * 2007-08-21 2009-02-11 주식회사 에스앤지바이오텍 스텐트용 약물 방출 멤브레인 및 이를 포함하는 내강확장용 약물 방출 스텐트
CN101234217B (zh) * 2008-03-07 2013-12-18 苏州盖依亚生物医药有限公司 一种功能性靶向治疗可降解的生物支架及其用途
EP2471497A4 (de) 2009-08-26 2013-10-09 Otsuka Medical Devices Co Ltd Medizinische vorrichtung zur platzierung in einem lumen und verfahren zu ihrer herstellung
CN102448406B (zh) * 2009-09-30 2014-08-27 泰尔茂株式会社 支架
CN101703813B (zh) * 2009-11-25 2012-11-28 南开大学 利用内源性no供体构建抗凝血性血管支架材料的方法
CA2786673A1 (en) * 2010-01-22 2011-07-28 Concept Medical Research Private Limited Insertable medical devices with a porous bed for delivering nano-carriers to a target site and methods of preparing the same
US10111830B2 (en) 2010-03-16 2018-10-30 Titan Pharmaceuticals, Inc. Heterogeneous implantable devices for drug delivery
EP2380604A1 (de) * 2010-04-19 2011-10-26 InnoRa Gmbh Verbesserte Beschichtungsformulierung zum Einritzen oder Schneiden von Ballonkathetern
KR101166885B1 (ko) * 2010-04-21 2012-07-18 주식회사 엠아이텍 듀얼 코팅 구조의 혈관용 스텐트
KR101146558B1 (ko) * 2010-04-30 2012-05-25 한국과학기술연구원 약물 방출 스텐트 표면의 나노 코팅 방법
US8920867B2 (en) * 2010-10-19 2014-12-30 Covidien Lp Methods of forming self-supporting films for delivery of therapeutic agents
US9861590B2 (en) * 2010-10-19 2018-01-09 Covidien Lp Self-supporting films for delivery of therapeutic agents
KR101262931B1 (ko) 2011-01-13 2013-05-09 전남대학교산학협력단 약물 방출 조절용 다중 코팅 스텐트 및 그의 제조 방법
KR101251362B1 (ko) 2011-04-06 2013-04-05 (주)시지바이오 이중코팅 스텐트의 제조 방법
KR20120135689A (ko) 2011-06-07 2012-12-17 (주) 태웅메디칼 약물 방출 스텐트 코팅제의 제조방법 및 이에 의해 제조된 약물 방출 스텐트 코팅제
KR101270143B1 (ko) 2011-06-16 2013-05-31 한국기계연구원 세포배양 지지체의 제조방법
KR101370607B1 (ko) * 2011-07-27 2014-03-07 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 전기방사를 이용한 비혈관용 약물 방출 스텐트 멤브레인 및 이의 제조방법
US20130303983A1 (en) * 2012-05-09 2013-11-14 Cook Medical Technologies Llc Coated medical devices including a water-insoluble therapeutic agent
KR101455162B1 (ko) * 2012-10-30 2014-10-28 주식회사 제노스 듀얼 코팅 스텐트
CN103705324B (zh) * 2013-12-31 2016-06-29 深圳市先健生物材料技术有限公司 血管涂层支架的制备方法
KR101622820B1 (ko) * 2014-01-21 2016-05-31 서울대학교산학협력단 성장인자와 약물의 이중방출이 가능한 금속 임플란트 및 이의 제조방법
CN104107459A (zh) * 2014-04-22 2014-10-22 吉林大学 具有时序响应功能的可降解高分子涂层支架及制造方法
TWI721956B (zh) 2014-10-28 2021-03-21 日商Jimro股份有限公司 藥劑溶出型支架
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
CN105232182A (zh) * 2015-10-22 2016-01-13 上海交通大学 一种载紫杉醇的乙烯-醋酸乙烯食管支架及其制备方法
CN105250048A (zh) * 2015-11-12 2016-01-20 辽宁垠艺生物科技股份有限公司 冠状动脉覆膜支架
KR101807938B1 (ko) 2016-02-04 2017-12-12 중앙대학교 산학협력단 하이드로젤계 약물 전달 시스템의 제조방법
KR101878853B1 (ko) * 2017-02-16 2018-07-16 한국과학기술연구원 선택적 세포 제어형 생체적합성 임플란트
CN106798953A (zh) * 2017-03-23 2017-06-06 苏州桓晨医疗科技有限公司 一种药物涂层支架干燥方法
EP3738623B1 (de) * 2018-01-09 2023-08-16 Shandong Huaan Biotechnology Co., Ltd. Abbaubarer vaskulärer stent zur vermeidung einer späten restenose
CN109172876B (zh) * 2018-09-21 2021-09-24 杭州巴泰医疗器械有限公司 一种同时带有快速释放药物和缓慢释放药物涂层的药物支架
CN109394399A (zh) * 2018-10-22 2019-03-01 乐畅医疗器械(上海)有限公司 一种药物缓释支架
CN111388155A (zh) * 2018-12-28 2020-07-10 先健科技(深圳)有限公司 植入式支架系统
CN110115649B (zh) * 2019-05-15 2021-05-18 四川兴泰普乐医疗科技有限公司 一种自显影可降解的血管支架
CN110115650B (zh) * 2019-05-15 2021-05-18 四川兴泰普乐医疗科技有限公司 一种自显影静电纺丝支架及其制备方法
EP3998049B1 (de) 2019-07-09 2024-08-21 Otsuka Medical Devices Co., Ltd. Wirkstofffreisetzender stents
US11478371B2 (en) * 2020-04-20 2022-10-25 Exovitra LLC Methods and systems for treatment of aneurysms
CN113041407B (zh) * 2021-03-15 2022-07-29 广州健康元呼吸药物工程技术有限公司 一种多层覆膜载药支架及其制备方法和用途
KR102668814B1 (ko) 2022-08-18 2024-05-29 강금용 3d 프린터를 이용한 생분해성 마그네슘을 포함하는 관상동맥용 스텐트의 제조방법 및 이의 제조방법으로 제조된 스텐트
CN115350338A (zh) * 2022-08-22 2022-11-18 万瑞飞鸿(北京)医疗器材有限公司 一种药物复合涂层、血管支架及其制备方法
CN115501397B (zh) * 2022-09-09 2023-10-20 苏州中天医疗器械科技有限公司 一种药物洗脱支架涂层及其制备方法与应用
CN119318552A (zh) * 2024-12-19 2025-01-17 鼎科医疗技术（苏州）有限公司 一种覆膜支架

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4491648A (en) * 1984-05-29 1985-01-01 Shell Oil Company Polymer blend composition
US5824048A (en) * 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5370682A (en) * 1993-04-26 1994-12-06 Meadox Medicals, Inc. Solid woven tubular prosthesis
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US7550005B2 (en) * 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US6174329B1 (en) * 1996-08-22 2001-01-16 Advanced Cardiovascular Systems, Inc. Protective coating for a stent with intermediate radiopaque coating
JP3865438B2 (ja) * 1996-09-03 2007-01-10 Ｔｄｋ株式会社 光ディスク
US6174330B1 (en) * 1997-08-01 2001-01-16 Schneider (Usa) Inc Bioabsorbable marker having radiopaque constituents
US6258117B1 (en) * 1999-04-15 2001-07-10 Mayo Foundation For Medical Education And Research Multi-section stent
US20070032853A1 (en) * 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US6541678B2 (en) * 1999-09-27 2003-04-01 Brennen Medical, Inc. Immunostimulating coating for surgical devices
DE10103324A1 (de) * 2000-02-15 2001-08-23 Siemens Ag Verfahren zur Isolation eines Hoch-T/sub c-Supraleiters sowie Verwendung des Verfahrens
US20030114918A1 (en) * 2000-04-28 2003-06-19 Garrison Michi E. Stent graft assembly and method
US6805711B2 (en) * 2000-06-02 2004-10-19 3F Therapeutics, Inc. Expandable medical implant and percutaneous delivery
KR100409017B1 (ko) * 2000-06-23 2003-12-06 주식회사 엘지화학 다성분계 복합 분리막 및 그의 제조방법
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US6746773B2 (en) 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
US20020051730A1 (en) 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
JP2003033439A (ja) * 2001-07-24 2003-02-04 Terumo Corp コーティングステントおよびその製造方法
US7011678B2 (en) * 2002-01-31 2006-03-14 Radi Medical Systems Ab Biodegradable stent
AU2003217329A1 (en) * 2002-02-05 2003-09-02 Thoratec Corporation Coated vascular prosthesis and methods of manufacture and use.
US20030153901A1 (en) * 2002-02-08 2003-08-14 Atrium Medical Corporation Drug delivery panel
JP2006507021A (ja) 2002-03-18 2006-03-02 メドトロニック・エイヴイイー・インコーポレーテッド 再狭窄の危険のある解剖学的部位へ抗増殖性組成物を送付するための医療用具
US20040051201A1 (en) * 2002-04-11 2004-03-18 Greenhalgh Skott E. Coated stent and method for coating by treating an electrospun covering with heat or chemicals
US20040230288A1 (en) * 2002-04-17 2004-11-18 Rosenthal Arthur L. Medical devices adapted for controlled in vivo structural change after implantation
AU2003239175A1 (en) * 2002-04-24 2003-11-10 Poly-Med, Inc. Multifaceted endovascular stent coating for preventing restenosis
US7083822B2 (en) * 2002-04-26 2006-08-01 Medtronic Vascular, Inc. Overlapping coated stents
WO2003099169A1 (en) 2002-05-20 2003-12-04 Orbus Medical Technologies Inc. Drug eluting implantable medical device
US7396539B1 (en) * 2002-06-21 2008-07-08 Advanced Cardiovascular Systems, Inc. Stent coatings with engineered drug release rate
DE10237571A1 (de) * 2002-08-13 2004-02-26 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Endovaskuläres Implantat mit aktiver Beschichtung
US20040034407A1 (en) * 2002-08-16 2004-02-19 John Sherry Covered stents with degradable barbs
JP4456322B2 (ja) * 2002-08-29 2010-04-28 川澄化学工業株式会社 ステント
US20040142910A1 (en) * 2002-10-21 2004-07-22 Aegis Biosciences Llc Sulfonated styrene copolymers for medical uses
EP1572029B1 (de) * 2002-11-07 2010-03-24 Abbott Laboratories Verfahren zum anbringen eines medikaments auf eine prothese mittels eines flüssigstrahls
US20060121080A1 (en) * 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
US20040180131A1 (en) * 2003-03-14 2004-09-16 Medtronic Ave. Stent coating method
US7163555B2 (en) * 2003-04-08 2007-01-16 Medtronic Vascular, Inc. Drug-eluting stent for controlled drug delivery
US20050107870A1 (en) * 2003-04-08 2005-05-19 Xingwu Wang Medical device with multiple coating layers
US20050070996A1 (en) * 2003-04-08 2005-03-31 Dinh Thomas Q. Drug-eluting stent for controlled drug delivery
US20040215313A1 (en) 2003-04-22 2004-10-28 Peiwen Cheng Stent with sandwich type coating
DE10325678A1 (de) * 2003-06-02 2004-12-23 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Verbindungssystem zur Verbindung eines Stents mit einem radioopaken Marker sowie Verfahren zur Herstellung einer Verbindung zwischen einem Stent und zwei oder mehreren radioopaken Markern
US20050119723A1 (en) * 2003-11-28 2005-06-02 Medlogics Device Corporation Medical device with porous surface containing bioerodable bioactive composites and related methods
US20060085062A1 (en) * 2003-11-28 2006-04-20 Medlogics Device Corporation Implantable stent with endothelialization factor
DE10361942A1 (de) * 2003-12-24 2005-07-21 Restate Patent Ag Radioopaker Marker für medizinische Implantate
US7243408B2 (en) * 2004-02-09 2007-07-17 Boston Scientific Scimed, Inc. Process method for attaching radio opaque markers to shape memory stent
US7591834B2 (en) * 2004-03-26 2009-09-22 Lawrence Livermore National Security, Llc Shape memory system with integrated actuation using embedded particles
US20050222671A1 (en) * 2004-03-31 2005-10-06 Schaeffer Darin G Partially biodegradable stent
US7541048B2 (en) * 2004-04-06 2009-06-02 Surmodics, Inc. Coating compositions for bioactive agents
US7803182B2 (en) * 2004-05-28 2010-09-28 Cordis Corporation Biodegradable vascular device with buffering agent
US20050288777A1 (en) * 2004-06-29 2005-12-29 Rhee Richard S Thermal conductor for adjustable cardiac valve implant
US20080183285A1 (en) * 2004-06-29 2008-07-31 Micardia Corporation Adjustable cardiac valve implant with selective dimensional adjustment
EP1778761B1 (de) * 2004-08-13 2021-09-29 Reva Medical, Inc. Inhärent strahlenundurchlässige bioresorbierbare polymere für verschiedene verwendungen
US20060147491A1 (en) * 2005-01-05 2006-07-06 Dewitt David M Biodegradable coating compositions including multiple layers
AU2006231652A1 (en) * 2005-04-05 2006-10-12 Elixir Medical Corporation Degradable implantable medical devices
US7357815B2 (en) * 2005-04-21 2008-04-15 Micardia Corporation Dynamically adjustable implants and methods for reshaping tissue
ATE487445T1 (de) * 2005-07-25 2010-11-15 Invatec Spa Endoluminale prothese mit bioresorbierbaren abschnitten
US20070055368A1 (en) * 2005-09-07 2007-03-08 Richard Rhee Slotted annuloplasty ring
US20070156230A1 (en) * 2006-01-04 2007-07-05 Dugan Stephen R Stents with radiopaque markers
DE102006038232A1 (de) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Endoprothese und Verfahren zur Herstellung einer solchen
US20080065200A1 (en) * 2006-09-07 2008-03-13 Trireme Medical, Inc. Bifurcated prostheses having differential drug coatings
US20080102035A1 (en) * 2006-10-30 2008-05-01 Vipul Bhupendra Dave Medical device having discrete regions
DE102007015670A1 (de) * 2007-03-31 2008-10-02 Biotronik Vi Patent Ag Stent mit radial expandierbarem Grundkörper

Also Published As

Publication number Publication date
KR100511618B1 (ko) 2005-08-31
JP2006198390A (ja) 2006-08-03
CN1806857B (zh) 2010-05-05
EP1681035A1 (de) 2006-07-19
EP1681035B1 (de) 2011-10-19
US20060161242A1 (en) 2006-07-20
CN1806857A (zh) 2006-07-26
US8845716B2 (en) 2014-09-30
JP4897267B2 (ja) 2012-03-14

Similar Documents

Publication Publication Date Title
ATE529068T1 (de) Mehrschichtig beschichteter stent zur kontrollierten freisetzung von wirkstoffen und verfahren zu seiner herstellung
CA2570444C (en) Absorbable stent comprising coating for controlling degradation and maintaining ph neutrality
ATE500854T1 (de) Beschichtete medizinische vorrichtungen und verfahren zu ihrer herstellung
US8652506B2 (en) Bio-degradable block co-polymers for controlled release
WO2005069966A3 (en) Vascular grafts with amphiphilic block copolymer coatings
US20070134288A1 (en) Anti-adhesion agents for drug coatings
US20050033414A1 (en) Drug-eluting stent with multi-layer coatings
DE60231231D1 (de) Therapeutische beschichtung für ein intravaskuläres implantat
US20100119578A1 (en) Extracellular matrix modulating coatings for medical devices
ATE389423T1 (de) Beschichtungen für implantierbare vorrichtungen enthaltend blockcopolymeren aus milchsäure und ethylenglykol
Puskas et al. Drug‐eluting stent coatings
JP2004523275A5 (de)
WO2006053007A3 (en) Antimicrobial needle coating for extended infusion
ATE425777T1 (de) Stents mit wirkstofffreisetzungsbeschichtungen
WO2008088456A3 (en) Methods, compositions and devices for treating leasioned sites using bioabsorbable carriers
WO2006020742A3 (en) Medical devices having nanoporous layers and methods for making the same
WO2004000379A8 (en) Stent coatings with sustained drug release rate
WO2006049907A3 (en) Implantable devices comprising biologically absorbable star polymers
ATE464025T1 (de) Herstellungsverfahren für medizinprodukte mit nanoporösen schichten
WO2007058841A1 (en) Coated and imprinted medical devices and methods of making the same
WO2004101018A8 (en) Stent coatings comprising hydrophilic additives
EP1832301A3 (de) Beschichtungen für implantierbare medizinische Vorrichtungen
WO2002062335A3 (en) Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts
CN101549187A (zh) 采用治疗剂液体制剂的局部和/或区域递送装置
WO2006047378A3 (en) Biocompatible and hemocompatible amphiphilic coatings for drug deliver

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties