ATE513045T1 - Stamm von escherichia coli überproduzierend l- threonine, und verfahren zur herstellung von l- threoninen durch fermentation - Google Patents
Stamm von escherichia coli überproduzierend l- threonine, und verfahren zur herstellung von l- threoninen durch fermentationInfo
- Publication number
- ATE513045T1 ATE513045T1 AT01977282T AT01977282T ATE513045T1 AT E513045 T1 ATE513045 T1 AT E513045T1 AT 01977282 T AT01977282 T AT 01977282T AT 01977282 T AT01977282 T AT 01977282T AT E513045 T1 ATE513045 T1 AT E513045T1
- Authority
- AT
- Austria
- Prior art keywords
- threonines
- fermentation
- strain
- producing
- escherichia coli
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23588400P | 2000-09-28 | 2000-09-28 | |
PCT/US2001/030558 WO2002026993A1 (en) | 2000-09-28 | 2001-09-28 | Escherichia coli strains which over-produce l-threonine and processes for the production of l-threonine by fermentation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE513045T1 true ATE513045T1 (de) | 2011-07-15 |
Family
ID=22887268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01977282T ATE513045T1 (de) | 2000-09-28 | 2001-09-28 | Stamm von escherichia coli überproduzierend l- threonine, und verfahren zur herstellung von l- threoninen durch fermentation |
Country Status (8)
Country | Link |
---|---|
US (4) | US7220571B2 (de) |
EP (1) | EP1322765B1 (de) |
AT (1) | ATE513045T1 (de) |
AU (2) | AU9641501A (de) |
BR (1) | BRPI0114101B1 (de) |
CA (1) | CA2423870C (de) |
MX (1) | MXPA03002683A (de) |
WO (1) | WO2002026993A1 (de) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4380029B2 (ja) * | 2000-07-05 | 2009-12-09 | 味の素株式会社 | 微生物を利用した物質の製造法 |
US6562601B2 (en) | 2000-08-31 | 2003-05-13 | Degussa Ag | Fermentation process for the preparation of L-threonine |
MXPA03000585A (es) * | 2000-08-31 | 2003-06-06 | Degussa | Proceso de fermentacion para la preparacion de l-treonina. |
AU2002345081A1 (en) * | 2001-07-18 | 2003-03-03 | Degussa Ag | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family |
KR100547882B1 (ko) | 2002-02-26 | 2006-02-01 | 삼성전자주식회사 | 안테나 선택 다이버시티를 지원하는 이동통신시스템에서순방향 채널 상태 정보를 송수신하는 방법 및 장치 |
DE10247437A1 (de) * | 2002-10-11 | 2004-04-29 | Consortium für elektrochemische Industrie GmbH | Feedback-resistente Homoserin-Transsuccinylasen |
DE10249642A1 (de) * | 2002-10-24 | 2004-05-13 | Consortium für elektrochemische Industrie GmbH | Feedback-resistente Homoserin-Transsuccinylasen mit modifiziertem C-Terminus |
US7291482B2 (en) * | 2002-12-20 | 2007-11-06 | E.I. Du Pont De Nemours And Company | Mutations affecting plasmid copy number |
RU2273666C2 (ru) * | 2003-02-26 | 2006-04-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Способ получения l-аминокислот методом ферментации смеси глюкозы и пентоз |
WO2005014842A1 (en) * | 2003-08-01 | 2005-02-17 | Degussa Ag | Process for the preparation of l-threonine |
WO2005023999A1 (en) * | 2003-09-06 | 2005-03-17 | Cj Corporation | A method for producing l-threonine |
KR100478468B1 (ko) * | 2003-09-06 | 2005-03-23 | 씨제이 주식회사 | L―쓰레오닌의 제조방법 |
JP4380305B2 (ja) * | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
CN101243177B (zh) * | 2004-01-30 | 2012-12-05 | 味之素株式会社 | 生产l-氨基酸的微生物和生产l-氨基酸的方法 |
US20050181488A1 (en) * | 2004-02-12 | 2005-08-18 | Akhverdian Valery Z. | Method for producing L-threonine using bacteria belonging to the genus Escherichia |
US7723097B2 (en) * | 2005-03-11 | 2010-05-25 | Archer-Daniels-Midland Company | Escherichia coli strains that over-produce L-threonine and processes for their production |
WO2007001982A1 (en) * | 2005-06-20 | 2007-01-04 | Archer-Daniels-Midland Company | Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals |
WO2007017710A1 (en) * | 2005-08-11 | 2007-02-15 | Metabolic Explorer | Process for the preparation of aspartate and derived amino acids like lysine, threonine, isoleucine, methionine, homoserine, or valine employing a microorganism with enhanced isocitrate lyase and/or malate synthase expression |
JP2007097956A (ja) * | 2005-10-06 | 2007-04-19 | Toshie Tsuchiya | 生体組織補填材とその製造方法 |
DK2314710T3 (en) * | 2006-01-04 | 2016-06-13 | Metabolic Explorer Sa | A process for the production of methionine by culturing a microorganism modified to enhance the production of cysteine |
JP2009118740A (ja) | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
EP1710317A3 (de) | 2006-07-13 | 2007-02-21 | Degussa AG | Verfahren zur Herstellung von L-Threonin und L-Homoserin |
KR20080010905A (ko) * | 2006-07-28 | 2008-01-31 | 씨제이 주식회사 | L-쓰레오닌 생합성 경로의 속도제한 단계를 담당하는효소의 활성이 강화된 l-쓰레오닌 생산 미생물 및 이를이용한 l-쓰레오닌 생산 방법 |
KR100837842B1 (ko) * | 2006-08-10 | 2008-06-13 | 씨제이제일제당 (주) | 아스파테이트 세미알데히드 디하이드로게나아제 활성이증가된 l-쓰레오닌 생산 미생물 및 이를 이용한l-쓰레오닌 생산 방법 |
JP2010017082A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2010088301A (ja) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸または核酸の製造方法 |
EP1975241A1 (de) | 2007-03-29 | 2008-10-01 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
BRPI0816429A2 (pt) | 2007-09-04 | 2019-09-24 | Ajinomoto Kk | microorganismo, e, método para a produção de um l-aminoácido. |
DE102007044134A1 (de) | 2007-09-15 | 2009-03-19 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
DE102007052270A1 (de) | 2007-11-02 | 2009-05-07 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
EP2060636A1 (de) | 2007-11-14 | 2009-05-20 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
KR20100120663A (ko) | 2008-01-23 | 2010-11-16 | 아지노모토 가부시키가이샤 | L-아미노산의 제조법 |
DE102008002309A1 (de) | 2008-06-09 | 2009-12-10 | Evonik Degussa Gmbh | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
DE102008044768A1 (de) | 2008-08-28 | 2010-03-04 | Evonik Degussa Gmbh | Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
PE20110369A1 (es) | 2008-09-08 | 2011-06-24 | Ajinomoto Kk | Un microorganismo que produce l-aminoacido y un metodo para producir un l-aminoacido |
JP2012029565A (ja) | 2008-11-27 | 2012-02-16 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
EP2267145A1 (de) | 2009-06-24 | 2010-12-29 | Evonik Degussa GmbH | Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae |
BRPI1014661B1 (pt) | 2009-07-29 | 2020-12-15 | Ajinomoto Co., Inc. | Método para produzir um l-aminoácido |
JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
EP2363489A1 (de) | 2010-03-03 | 2011-09-07 | Technische Universität Hamburg-Harburg | Enzym Aspartokinase III mit verringerter L-Lysin Feedback-Inhibierung |
EP2374873A1 (de) | 2010-04-08 | 2011-10-12 | Technische Universität Hamburg-Harburg | Modifizierte Aspartatkinase aus dem Corynebacterium und ihre Verwendung bei der Aminosäureherstellung |
EP2495317A1 (de) | 2011-03-01 | 2012-09-05 | Technische Universität Hamburg-Harburg | Modifizierte Phosphoenolpyruvate-Carboxylase aus Corynebacterium glutamicum und Verwendungen derselben |
EP2868745B1 (de) | 2013-05-13 | 2017-06-21 | Ajinomoto Co., Inc. | Verfahren zur Herstellung einer L-Aminosäure |
JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのl−アミノ酸の製造方法 |
CN106459857B (zh) | 2013-10-02 | 2019-04-19 | 味之素株式会社 | 氨控制装置及氨控制方法 |
EP2886651B1 (de) | 2013-10-21 | 2018-08-22 | Ajinomoto Co., Inc. | Verfahren zur herstellung von l-aminosäure |
BR112016008830B1 (pt) | 2013-10-23 | 2023-02-23 | Ajinomoto Co., Inc | Método para produzir uma substância alvo |
KR20190104342A (ko) | 2016-12-14 | 2019-09-09 | 바게닝겐 유니버시테이트 | 열안정성 cas9 뉴클레아제 |
JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | L-アミノ酸の製造法 |
EP3608409A1 (de) | 2018-08-09 | 2020-02-12 | Evonik Operations GmbH | Verfahren zur herstellung von l-aminosäuren unter verwendung verbesserter stämme aus der familie der enterobacteriaceae |
US11053526B2 (en) | 2018-08-09 | 2021-07-06 | Evonik Operations Gmbh | Process for preparing L amino acids using improved strains of the enterobacteriaceae family |
RU2697219C1 (ru) * | 2018-09-28 | 2019-08-13 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) | Рекомбинантный штамм бактерии Escherichia coli - продуцент L-треонина |
EP3861109A1 (de) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Verfahren zur herstellung einer zielsubstanz durch bakterielle fermentation |
WO2020171227A1 (en) | 2019-02-22 | 2020-08-27 | Ajinomoto Co., Inc. | METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE |
JP2022526181A (ja) | 2019-04-05 | 2022-05-23 | 味の素株式会社 | L-アミノ酸の製造方法 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3375173A (en) | 1964-07-01 | 1968-03-26 | Chugai Pharmaceutical Co Ltd | Fermentation process for the production of l-threonine |
FR1580549A (de) | 1967-07-28 | 1969-09-05 | ||
JPS516752B2 (de) * | 1972-01-25 | 1976-03-02 | ||
JPS53101591A (en) | 1977-02-15 | 1978-09-05 | Ajinomoto Co Inc | Preparation of l-threonine by fermentation |
SU943282A1 (ru) | 1979-07-13 | 1982-07-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Способ получени L-треонина |
JPS55131397A (en) | 1979-04-02 | 1980-10-13 | Ajinomoto Co Inc | Preparation of l-threonine by fermentation |
JPS55156591A (en) | 1979-05-23 | 1980-12-05 | Ajinomoto Co Inc | Method for stabilizing property of bacteria containing plasmid |
JPS56134993A (en) | 1980-03-21 | 1981-10-22 | Tanabe Seiyaku Co Ltd | Preparation of l-threonine by fermentation method |
US5236831A (en) | 1981-12-29 | 1993-08-17 | Kiowa Hakko Kogyo Co., Ltd. | Amino acid synthesis in corynebacteria using E. coli genes |
US4601983A (en) | 1983-06-15 | 1986-07-22 | Ajinomoto Co., Inc. | Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine |
JPH0783714B2 (ja) | 1983-08-29 | 1995-09-13 | 味の素株式会社 | 発酵法によるl―アミノ酸の製造法 |
JPS6062982A (ja) | 1983-09-14 | 1985-04-11 | Ajinomoto Co Inc | 組換えdνa,該組換えdνaを有する細菌及び該細菌を用いるl−スレオニン又はl−イソロイシンの製造法 |
US4764276A (en) | 1984-07-30 | 1988-08-16 | Advanced Separation Technologies Incorporated | Device for continuous contacting of fluids and solids |
JPH0746994B2 (ja) | 1984-10-04 | 1995-05-24 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
US4808317A (en) | 1985-03-19 | 1989-02-28 | Advanced Separation Technologies Incorporated | Process for continuous contacting of fluids and solids |
EP0205849B1 (de) | 1985-05-13 | 1991-12-04 | Toray Industries, Inc. | Verfahren zur Herstellung von L-Threonin durch Fermentation |
US5264353A (en) | 1985-08-23 | 1993-11-23 | Toray Industries, Inc. | Process for producing L-threonine by fermentation |
DE3684383D1 (de) | 1985-08-23 | 1992-04-23 | Toray Industries | Verfahren zur herstellung von l-threonin durch fermentation. |
US5342766A (en) | 1985-08-26 | 1994-08-30 | Toray Industries, Inc. | Process for producing L-threonine by fermentation with P. rettgeri. |
DE3689437T2 (de) | 1985-10-18 | 1994-04-14 | Toray Industries | Plasmid mit breitem Wirtspektrum. |
US5017483A (en) | 1986-02-20 | 1991-05-21 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing L-threonine |
US5164307A (en) | 1987-01-23 | 1992-11-17 | Ajinomoto Co., Inc. | Process for producing L-amino acids by fermentation |
DE3888076T2 (de) | 1987-10-15 | 1994-07-14 | Mitsubishi Petrochemical Co | Verfahren zur Herstellung von L-Threonin. |
JP2600750B2 (ja) | 1988-01-21 | 1997-04-16 | 味の素株式会社 | 発酵法によるl―スレオニンの製造法 |
DE3891417T1 (de) | 1988-10-25 | 1991-01-10 | Vnii Genetiki Selektsii Promy | Stamm der bakterien escherichia coli bkiim b-3996, produziert von l-threonin |
JP2578492B2 (ja) | 1988-11-10 | 1997-02-05 | 協和醗酵工業株式会社 | 発酵法によるl−スレオニンの製造法 |
JPH0477090A (ja) | 1990-07-16 | 1992-03-11 | Sharp Corp | 指令入力装置 |
JP3151073B2 (ja) | 1992-02-25 | 2001-04-03 | 協和醗酵工業株式会社 | 発酵法によるアミノ酸の製造法 |
DE69219775T3 (de) | 1992-10-14 | 2004-08-05 | Ajinomoto Co., Inc. | Neuartiges L-threoninproduzierendes Mikrobakterium und eine Herstellungsmethode für L-Threonin |
US5998178A (en) | 1994-05-30 | 1999-12-07 | Ajinomoto Co., Ltd. | L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation |
CN1124340C (zh) | 1994-08-30 | 2003-10-15 | 味之素株式会社 | L-缬氨酸和l-亮氨酸的生产方法 |
US5939307A (en) | 1996-07-30 | 1999-08-17 | The Archer-Daniels-Midland Company | Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production |
US6984512B1 (en) * | 1999-08-02 | 2006-01-10 | Archer-Daniels-Midland Company | Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production |
-
2001
- 2001-09-26 US US09/962,303 patent/US7220571B2/en not_active Expired - Lifetime
- 2001-09-28 BR BRPI0114101A patent/BRPI0114101B1/pt not_active IP Right Cessation
- 2001-09-28 CA CA2423870A patent/CA2423870C/en not_active Expired - Fee Related
- 2001-09-28 MX MXPA03002683A patent/MXPA03002683A/es active IP Right Grant
- 2001-09-28 AT AT01977282T patent/ATE513045T1/de not_active IP Right Cessation
- 2001-09-28 AU AU9641501A patent/AU9641501A/xx active Pending
- 2001-09-28 WO PCT/US2001/030558 patent/WO2002026993A1/en active Application Filing
- 2001-09-28 EP EP01977282A patent/EP1322765B1/de not_active Expired - Lifetime
- 2001-09-28 AU AU2001296415A patent/AU2001296415B2/en not_active Ceased
-
2007
- 2007-04-13 US US11/786,818 patent/US7767431B2/en not_active Expired - Fee Related
-
2008
- 2008-03-19 US US12/051,064 patent/US7687253B2/en not_active Expired - Fee Related
-
2010
- 2010-06-28 US US12/824,743 patent/US8101386B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
MXPA03002683A (es) | 2003-09-10 |
US20100267095A1 (en) | 2010-10-21 |
US7687253B2 (en) | 2010-03-30 |
AU9641501A (en) | 2002-04-08 |
CA2423870C (en) | 2014-06-03 |
BR0114101A (pt) | 2006-11-14 |
US7220571B2 (en) | 2007-05-22 |
US20080166788A1 (en) | 2008-07-10 |
WO2002026993A1 (en) | 2002-04-04 |
BRPI0114101B1 (pt) | 2015-09-15 |
AU2001296415B2 (en) | 2007-01-04 |
US20020106800A1 (en) | 2002-08-08 |
CA2423870A1 (en) | 2002-04-04 |
US8101386B2 (en) | 2012-01-24 |
EP1322765A1 (de) | 2003-07-02 |
EP1322765B1 (de) | 2011-06-15 |
US7767431B2 (en) | 2010-08-03 |
US20070254337A1 (en) | 2007-11-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE513045T1 (de) | Stamm von escherichia coli überproduzierend l- threonine, und verfahren zur herstellung von l- threoninen durch fermentation | |
ID19402A (id) | Strain baru dari eschirichia coli, metoda pembuatan dan penggunaan daripadanya dalam proses fermentasi untuk produksi l-threonine | |
DE60235810D1 (de) | Verfahren zur herstellung von l-aminosäuren durch enterobacteriaceae-stämme mit verstärkter expression des fba-gens | |
ATE441714T1 (de) | Verfahren zur herstellung von l-aminosäuren durch enterobakteriaceae-stämmen mit verstärkter exprimierung des rsea-gens | |
DK1382684T3 (da) | Fremgangsmåde til fermentativ fremstilling af aminosyrer og aminosyrederivater af phosphorglycerat - familien | |
AU2002251060A1 (en) | Process for the production of l-amino acids using strains of the family enterobacteriaceae that contain an attenuated dgsa gene | |
PL1608764T3 (pl) | Sposób wytwarzania L-aminokwasów przy zastosowaniu szczepów rodziny Enterobacteriaceae z nadekspresją genu GALP, kodującego symporter galaktoza proton | |
ATE431847T1 (de) | Varianten der 3-phosphoglyceratdehydrogenase mit reduzierter hemmung durch l-serin und dafür codierende gene | |
DE60225353D1 (de) | Verfahren zur Herstellung von L-Aminosäuren mit Hilfe von Stämmen der Familie Enterobacteriaceae, die ein verstärktes fadR-Gen enthalten. | |
DE602004029135D1 (de) | Mikrobielles Verfahren zur Herstellung von Arginin | |
ATE518962T1 (de) | Verfahren zur herstellung von d-serin | |
ATE549405T1 (de) | Bakterienmutanten zur l-lysinherstellung | |
ATE536411T1 (de) | Verfahren zur herstellung von nichtaromatischen l-aminosäuren durch stämme aus der famile der enterobacteriaceae | |
WO2007046943A3 (en) | Method of producing biotin | |
DE60321865D1 (de) | Verfahren zur fermentativen Herstellung von L-Aminosäuren durch Enterobakteriaceae-Stämmen mit verstärkter Exprimierung des rseB-Gens | |
ATE428794T1 (de) | Verfahren zur herstellung von l-aminosäuren unter verwendung von stämmen der familie enterobacteriaceae | |
DE60140373D1 (de) | Fermentationsverfahren zur herstellung von l-aminosäuren unter verwendung von stämmen aus der familie der enterobacteriaceae |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |