ATE502920T1 - Indole und ihre therapeutische verwendung - Google Patents
Indole und ihre therapeutische verwendungInfo
- Publication number
- ATE502920T1 ATE502920T1 AT08862784T AT08862784T ATE502920T1 AT E502920 T1 ATE502920 T1 AT E502920T1 AT 08862784 T AT08862784 T AT 08862784T AT 08862784 T AT08862784 T AT 08862784T AT E502920 T1 ATE502920 T1 AT E502920T1
- Authority
- AT
- Austria
- Prior art keywords
- fluoro
- alkyl
- chloro
- phenyl
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0724429A GB0724429D0 (en) | 2007-12-14 | 2007-12-14 | Compounds |
| GB0806083A GB0806083D0 (en) | 2008-04-03 | 2008-04-03 | Compounds |
| GB0814910A GB0814910D0 (en) | 2008-08-14 | 2008-08-14 | Compounds |
| PCT/GB2008/004107 WO2009077728A1 (en) | 2007-12-14 | 2008-12-12 | Indoles and their therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502920T1 true ATE502920T1 (de) | 2011-04-15 |
Family
ID=40328483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08862784T ATE502920T1 (de) | 2007-12-14 | 2008-12-12 | Indole und ihre therapeutische verwendung |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8394836B2 (de) |
| EP (2) | EP2229358B1 (de) |
| JP (1) | JP5327762B2 (de) |
| CN (1) | CN101970405A (de) |
| AT (1) | ATE502920T1 (de) |
| AU (1) | AU2008337342B2 (de) |
| BR (1) | BRPI0820872A2 (de) |
| CA (1) | CA2707785C (de) |
| CY (2) | CY1111585T1 (de) |
| DE (1) | DE602008005796D1 (de) |
| DK (2) | DK2229358T3 (de) |
| EA (1) | EA017573B1 (de) |
| ES (1) | ES2386340T3 (de) |
| HR (2) | HRP20110414T1 (de) |
| IL (1) | IL206087A (de) |
| MX (1) | MX2010006341A (de) |
| NZ (1) | NZ585888A (de) |
| PL (2) | PL2327693T3 (de) |
| PT (2) | PT2327693E (de) |
| SI (2) | SI2327693T1 (de) |
| WO (1) | WO2009077728A1 (de) |
| ZA (1) | ZA201003872B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0505048D0 (en) | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
| RU2458918C2 (ru) | 2006-07-22 | 2012-08-20 | Оксаген Лимитед | Соединения, обладающие антагонистической активностью по отношению к crth2 |
| US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| EP2250161B1 (de) * | 2008-01-18 | 2013-10-16 | Atopix Therapeutics Limited | Verbindungen mit crth2-antagonisten-wirkung |
| WO2009093029A1 (en) | 2008-01-22 | 2009-07-30 | Oxagen Limited | Compounds having crth2 antagonist activity |
| CN102791689B (zh) | 2010-03-22 | 2014-10-29 | 埃科特莱茵药品有限公司 | 3-（杂芳基-氨基）-1,2,3,4-四氢-9h-咔唑衍生物及其作为前列腺素d2受体调节剂的用途 |
| US20130259830A1 (en) * | 2010-07-12 | 2013-10-03 | Ironwood Pharmaceuticals, Inc. | Crth2 modulators |
| KR101928595B1 (ko) | 2011-04-14 | 2018-12-12 | 이도르시아 파마슈티컬스 리미티드 | 7-(헤테로아릴-아미노)-6,7,8,9-테트라히드로피리도［1,2-ａ］인돌 아세트산 유도체 및 프로스타글란딘 ｄ2 수용체 조절자로서의 이의 용도 |
| US9233098B2 (en) * | 2011-11-17 | 2016-01-12 | Kbp Biosciences Co., Ltd. | Nitrogen-containing fused ring compounds as CRTH2 antagonists |
| EA026456B1 (ru) * | 2011-12-16 | 2017-04-28 | Атопикс Терапьютикс Лимитед | Фармацевтическая композиция на основе антагониста crth2 и ингибитора протонного насоса для лечения эозинофильного эзофагита |
| WO2014066568A1 (en) | 2012-10-24 | 2014-05-01 | Winthrop-University Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
| GB201322273D0 (en) * | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
| HUE039614T2 (hu) | 2014-03-17 | 2019-01-28 | Idorsia Pharmaceuticals Ltd | Azaindol-ecetsav-származékok és prosztaglandin D2 receptor modulátorokként történõ alkalmazásuk |
| GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
| JPWO2015190316A1 (ja) * | 2014-06-09 | 2017-04-20 | 住友化学株式会社 | ピリジン化合物の製造方法 |
| ES2867757T3 (es) | 2015-09-15 | 2021-10-20 | Idorsia Pharmaceuticals Ltd | Formas cristalinas |
| EP3399968B8 (de) | 2016-01-07 | 2021-12-01 | Xuanzhu Biopharmaceutical Co., Ltd. | Selektive inhibitoren von klinisch wichtigen mutanten der egfr-tyrosin-kinase |
| WO2017119732A1 (en) | 2016-01-08 | 2017-07-13 | Samsung Electronics Co., Ltd. | Electronic device and operating method thereof |
| JP7112957B2 (ja) | 2016-03-09 | 2022-08-04 | ベイジン パーカンズ オンコロジー カンパニー リミテッド | 腫瘍細胞懸濁培養及び関連方法 |
| RU2756270C2 (ru) * | 2016-07-21 | 2021-09-29 | Чиа Тай Тянцин Фармасьютикал Груп Ко., Лтд. | Производное индола, используемое в качестве ингибитора CRTH2 |
| CA3075688A1 (en) | 2017-09-13 | 2019-03-21 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
| CN109096186B (zh) * | 2018-09-29 | 2020-08-04 | 中南大学 | 一种2-芳磺酰基喹啉衍生物的合成方法 |
| EP4070113A4 (de) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | Beurteilung von präeklampsie unter verwendung von tests für freien und dissoziierten plazentalen wachstumsfaktor |
| CN113425714B (zh) * | 2021-08-04 | 2022-04-26 | 华南师范大学 | 吲哚乙酸在制备防治慢性阻塞性肺病药物中的应用 |
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| JP2001163899A (ja) | 1999-12-09 | 2001-06-19 | Natl Inst Of Sericultural & Entomological Science | 機能性絹フィブロインの製造方法とその利用 |
| GB0028383D0 (en) | 2000-11-21 | 2001-01-03 | Novartis Ag | Organic compounds |
| EP1241176A1 (de) | 2001-03-16 | 2002-09-18 | Pfizer Products Inc. | Purinderivate zur Behandlung von Ischämie |
| EP1424325A4 (de) | 2001-09-07 | 2005-12-21 | Ono Pharmaceutical Co | Indolderivate, verfahren zu deren herstellung und arzneimittel, die diese als wirkstoff enthalten |
| WO2003053930A1 (en) | 2001-12-20 | 2003-07-03 | Bayer Healthcare Ag | 1,4-dihydro-1,4-diphenylpyridine derivatives |
| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
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| AU2003231513A1 (en) | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Pgd2 receptor antagonist |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
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| EP1413306A1 (de) | 2002-10-21 | 2004-04-28 | Warner-Lambert Company LLC | Tetrahydrochinolin-Derivate als CRTH2 Antagonisten |
| AU2003269327A1 (en) | 2002-10-21 | 2004-05-04 | Warner-Lambert Company Llc | Tetrahydroquinoline derivatives as crth2 antagonists |
| US7321001B2 (en) | 2002-12-20 | 2008-01-22 | Amgen Inc. | Asthma and allergic inflammation modulators |
| EP1435356A1 (de) | 2003-01-06 | 2004-07-07 | Warner-Lambert Company LLC | Chinolinderivate als CRTH2-Antagonisten |
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| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301009D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
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| SE0302232D0 (sv) | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| SE0302487D0 (sv) | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | Novel compounds |
| WO2005040112A1 (en) | 2003-10-14 | 2005-05-06 | Oxagen Limited | Compounds with pgd2 antagonist activity |
| JP2007508363A (ja) | 2003-10-14 | 2007-04-05 | オキサジェン リミテッド | Ｃｒｔｈ２アンタゴニスト活性を有する化合物 |
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| GB2407318A (en) | 2003-10-23 | 2005-04-27 | Oxagen Ltd | Substituted Indol-3-yl acetic acid derivatives |
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| ES2345662T3 (es) | 2004-03-11 | 2010-09-29 | Actelion Pharmaceuticals Ltd. | Derivados de acido indol-1-il-acetico. |
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| WO2005102612A2 (en) | 2004-04-20 | 2005-11-03 | Acco Brands Usa Llc | Stapler |
| GB0409921D0 (en) | 2004-05-04 | 2004-06-09 | Novartis Ag | Organic compounds |
| EP1758579A1 (de) | 2004-05-29 | 2007-03-07 | 7TM Pharma A/S | Crth2-rezeptor-liganden für medizinische anwendungen |
| EA200700712A1 (ru) | 2004-09-21 | 2008-02-28 | Эсерсис, Инк. | Производные индолуксусной кислоты, способ получения таких производных (варианты), фармацевтическая композиция, набор на их основе, способ ингибирования связывания эндогенных лигандов и способ лечения заболеваний и расстройств, восприимчивых к ингибированию связывания эндогенных лигандов с рецептором crth-2 |
| UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
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| GB0502258D0 (en) | 2005-02-03 | 2005-03-09 | Argenta Discovery Ltd | Compounds and their use |
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| GB0505048D0 (en) | 2005-03-11 | 2005-04-20 | Oxagen Ltd | Compounds with PGD antagonist activity |
| GB0510584D0 (en) | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| GB0510585D0 (en) | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
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| GB0521275D0 (en) | 2005-10-19 | 2005-11-30 | Argenta Discovery Ltd | 3-Aminoindole compounds |
| WO2007062678A1 (en) | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
| GB0524428D0 (en) | 2005-11-30 | 2006-01-11 | 7Tm Pharma As | Medicinal use of receptor ligands |
| GB0525141D0 (en) | 2005-12-09 | 2006-01-18 | Novartis Ag | Organic compounds |
| CN102558021A (zh) * | 2006-05-26 | 2012-07-11 | 阿斯利康(瑞典)有限公司 | 联芳基或芳基-杂芳基取代的吲哚类化合物 |
| GB0611695D0 (en) | 2006-06-13 | 2006-07-26 | Novartis Ag | Organic compounds |
| RU2458918C2 (ru) * | 2006-07-22 | 2012-08-20 | Оксаген Лимитед | Соединения, обладающие антагонистической активностью по отношению к crth2 |
| JP2010513429A (ja) | 2006-12-21 | 2010-04-30 | アージェンタ ディスカバリー リミテッド | Ｃｒｔｈ２アンタゴニスト |
| EA200970875A1 (ru) | 2007-03-21 | 2010-04-30 | Арджента Орал Терапьютикс Лимитед | Производные индолизинуксусной кислоты в качестве антагонистов crth2 |
| WO2008119917A1 (en) | 2007-03-29 | 2008-10-09 | Argenta Discovery Limited | Quinoline derivatives as crth2 receptor ligands |
| DK2139881T3 (da) | 2007-04-04 | 2012-01-30 | Pulmagen Therapeutics Asthma Ltd | Quinoliner og deres terapeutiske anvendelse |
| GB0722203D0 (en) * | 2007-11-13 | 2007-12-19 | Oxagen Ltd | Use of CRTH2 antagonist compounds |
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2008
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- 2008-12-12 PT PT10193389T patent/PT2327693E/pt unknown
- 2008-12-12 AT AT08862784T patent/ATE502920T1/de active
- 2008-12-12 MX MX2010006341A patent/MX2010006341A/es active IP Right Grant
- 2008-12-12 EP EP08862784A patent/EP2229358B1/de not_active Not-in-force
- 2008-12-12 SI SI200830693T patent/SI2327693T1/sl unknown
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- 2008-12-12 PT PT08862784T patent/PT2229358E/pt unknown
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- 2008-12-12 NZ NZ585888A patent/NZ585888A/en not_active IP Right Cessation
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- 2008-12-12 AU AU2008337342A patent/AU2008337342B2/en not_active Ceased
- 2008-12-12 CN CN2008801267027A patent/CN101970405A/zh active Pending
- 2008-12-12 EA EA201070731A patent/EA017573B1/ru not_active IP Right Cessation
- 2008-12-12 SI SI200830260T patent/SI2229358T1/sl unknown
- 2008-12-12 BR BRPI0820872-7A patent/BRPI0820872A2/pt not_active Application Discontinuation
- 2008-12-12 PL PL10193389T patent/PL2327693T3/pl unknown
- 2008-12-12 DK DK08862784.9T patent/DK2229358T3/da active
- 2008-12-12 ES ES10193389T patent/ES2386340T3/es active Active
- 2008-12-12 EP EP10193389A patent/EP2327693B9/de not_active Not-in-force
- 2008-12-12 DK DK10193389.3T patent/DK2327693T3/da active
- 2008-12-12 PL PL08862784T patent/PL2229358T3/pl unknown
- 2008-12-12 WO PCT/GB2008/004107 patent/WO2009077728A1/en active Application Filing
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2010
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2011
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2012
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2013
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