ATE445704T1 - Expressionsvektor für tierische zellen - Google Patents
Expressionsvektor für tierische zellenInfo
- Publication number
- ATE445704T1 ATE445704T1 AT01957013T AT01957013T ATE445704T1 AT E445704 T1 ATE445704 T1 AT E445704T1 AT 01957013 T AT01957013 T AT 01957013T AT 01957013 T AT01957013 T AT 01957013T AT E445704 T1 ATE445704 T1 AT E445704T1
- Authority
- AT
- Austria
- Prior art keywords
- vector
- expression vector
- present
- animal cells
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4717—Plasma globulins, lactoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2000-0043996A KR100408844B1 (ko) | 2000-07-29 | 2000-07-29 | 동물세포 발현벡터 |
PCT/KR2001/001285 WO2002014525A2 (en) | 2000-07-29 | 2001-07-27 | Expression vector using for animal cell |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE445704T1 true ATE445704T1 (de) | 2009-10-15 |
Family
ID=19680759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01957013T ATE445704T1 (de) | 2000-07-29 | 2001-07-27 | Expressionsvektor für tierische zellen |
Country Status (10)
Country | Link |
---|---|
US (1) | US7422874B2 (de) |
EP (1) | EP1392835B1 (de) |
JP (1) | JP4138479B2 (de) |
KR (1) | KR100408844B1 (de) |
CN (1) | CN1262663C (de) |
AT (1) | ATE445704T1 (de) |
AU (1) | AU2001278797A1 (de) |
DE (1) | DE60140218D1 (de) |
ES (1) | ES2333774T3 (de) |
WO (1) | WO2002014525A2 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG141239A1 (en) * | 2001-01-26 | 2008-04-28 | Selexis Sa | Matrix attachment regions and methods for use thereof |
NZ571508A (en) | 2002-05-24 | 2010-05-28 | Schering Corp | Neutralizing human anti-IGFR antibody |
WO2004027072A2 (en) * | 2002-09-20 | 2004-04-01 | Novo Nordisk A/S | Method for making recombinant proteins |
US6933136B2 (en) | 2002-09-20 | 2005-08-23 | Novo Nordisk A/S | Method for making recombinant proteins |
KR100755931B1 (ko) * | 2003-06-11 | 2007-09-06 | (주)두비엘 | 고분자형 만노스 결합형 렉틴의 대량 생산방법 및 상기방법으로 제조된 만노스 결합형 렉틴 재조합 단백질의제제화 |
US7135338B2 (en) * | 2003-06-11 | 2006-11-14 | Dobeel Corporation | Methods for overexpression of high molecular weight form of mannose binding lectin (MBL) and a specific formulation for active treatment for systemic infection with microorganism |
KR101229989B1 (ko) | 2003-10-24 | 2013-02-06 | 셀렉시스 에스. 에이. | Mar 서열의 복합 트랜스펙션 방법에 의한 포유동물 세포에서의 고효율 유전자 전달 및 발현 |
US7326567B2 (en) | 2003-11-12 | 2008-02-05 | Schering Corporation | Plasmid system for multigene expression |
AR046639A1 (es) | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
BRPI0419151A (pt) * | 2004-10-28 | 2007-12-11 | Dobeel Co Ltd | método para a produção em massa de lectina ligante de manose multimérica |
DE602006014942D1 (de) * | 2005-03-04 | 2010-07-29 | Celltrion Inc | Expressionsvektor für tierische zelle mit wenigstens einer kopie von mar-dna-sequenzen am 3'-ende des transkriptionsterminationsbereichs eines gens sowie verfahren zur expression eines fremdgens unter verwendung des vektors |
KR100779761B1 (ko) * | 2005-10-28 | 2007-11-30 | 대한민국 | 인슐린 억제 및 사람 ide 유전자로 형질전환된 동물 및그 제조방법 |
KR100836745B1 (ko) * | 2007-01-31 | 2008-06-10 | (주)두비엘 | Hbv 백신 및 그의 제조 방법 |
WO2008153366A2 (en) | 2007-06-15 | 2008-12-18 | Mogam Biotechnology Research Institute | Method for manufacturing active recombinant blood coagulation factor ix |
CN101348786B (zh) * | 2007-07-20 | 2011-05-11 | 谭孟群 | 一种人β珠蛋白基因及其重组腺相关病毒载体 |
EP2304027A1 (de) * | 2008-06-10 | 2011-04-06 | ISIS Innovation Limited | Proteinexpression |
KR101054362B1 (ko) | 2008-07-03 | 2011-08-05 | 재단법인 목암생명공학연구소 | 재조합 단백질의 푸코스 함량을 감소시키는 방법 |
US8137933B2 (en) | 2008-11-12 | 2012-03-20 | Schering Corporation | Mammalian expression vector pUHAB |
EP2412810B1 (de) * | 2009-03-27 | 2015-07-08 | Hiroshima University | Verfahren zur amplifikation und hochgradigen expression eines zielgens in säugerzellen und kit zur durchführung dieses verfahrens |
JP2013505013A (ja) * | 2009-09-18 | 2013-02-14 | セレクシス エス.エー. | 強化導入遺伝子発現およびプロセッシングの産物および方法 |
US20130034875A1 (en) * | 2009-10-01 | 2013-02-07 | Toto Ltd. | Dna construct, and process for production of recombinant cho cell using same |
MX2012003816A (es) * | 2009-10-01 | 2012-07-04 | Toto Ltd | Construccion de adn y procedimiento para la generacion de celulas cho recombinantes usando la misma. |
JP5888616B2 (ja) | 2010-10-08 | 2016-03-22 | カディラ・ヘルスケア・リミテッド | 組換えタンパク質の高レベル発現用の発現ベクター |
WO2012134215A2 (ko) * | 2011-03-30 | 2012-10-04 | (주)팬젠 | 동물세포 발현벡터 |
US10175183B2 (en) | 2011-03-31 | 2019-01-08 | Kunimine Industries Co., Ltd. | Agent for searching for protein crystallization conditions and method of searching for protein crystallization conditions |
KR101420274B1 (ko) * | 2011-06-13 | 2014-07-21 | 주식회사 종근당 | Csp-b 5'sar 인자를 포함하는 동물세포 발현 벡터 및 이를 이용한 재조합 단백질의 제조방법 |
ES2806146T3 (es) | 2011-09-22 | 2021-02-16 | Amgen Inc | Proteínas de unión al antígeno CD27L |
MX355624B (es) * | 2011-12-22 | 2018-04-25 | Hoffmann La Roche | Combinaciones de elementos de vector de expresion, metodos novedosos de generacion de celulas de produccion y su uso para la produccion recombinante de polipeptidos. |
ES2791758T3 (es) | 2011-12-22 | 2020-11-05 | Hoffmann La Roche | Organización de vectores de expresión, procedimientos de generación de células de producción novedosos y su uso para la producción recombinante de polipéptidos |
AR091069A1 (es) | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
US9580486B2 (en) | 2013-03-14 | 2017-02-28 | Amgen Inc. | Interleukin-2 muteins for the expansion of T-regulatory cells |
WO2014144817A2 (en) | 2013-03-15 | 2014-09-18 | Amgen Inc. | Inhibitory polypeptides specific to wnt inhibitors |
CN103194455B (zh) * | 2013-04-08 | 2014-10-15 | 山东省农业科学院畜牧兽医研究所 | 高效表达的猪粒细胞巨噬细胞集落刺激因子基因及其表达蛋白的用途 |
CN110511279B (zh) | 2013-05-30 | 2024-03-29 | 基尼克萨制药有限公司 | 制瘤素m受体抗原结合蛋白 |
JP6668241B2 (ja) | 2013-09-05 | 2020-03-18 | アムジエン・インコーポレーテツド | 予測可能で、一貫性のある、且つ再現可能な糖型特性を示すFc含有分子 |
EP3041935A1 (de) | 2013-09-05 | 2016-07-13 | Sage Therapeutics, Inc. | Antisense-induzierter exon2-einschluss in saurer alpha-glucosidase |
KR101591823B1 (ko) | 2013-12-27 | 2016-02-04 | 재단법인 목암생명공학연구소 | 증가된 유전자 발현능을 갖는 발현벡터 |
EA201792250A1 (ru) | 2015-04-10 | 2018-05-31 | Эмджен Инк. | Мутеины интерлейкина-2 для роста регуляторных т-клеток |
CA2980189A1 (en) | 2015-04-24 | 2016-10-27 | Genentech, Inc. | Multispecific antigen-binding proteins |
CN108138147B (zh) | 2015-09-22 | 2022-11-01 | 豪夫迈·罗氏有限公司 | 含Fc蛋白的表达 |
KR20180069839A (ko) | 2015-10-08 | 2018-06-25 | 자임워크스 인코포레이티드 | 카파 및 람다 경사슬을 포함하는 항원-결합 폴리펩티드 구조체 및 이의 용도 |
BR112018007356A2 (pt) | 2015-11-02 | 2018-10-23 | Genentech Inc | métodos de produção de formas fucosiladas e não fucosiladas de uma proteína |
WO2017184529A1 (en) | 2016-04-18 | 2017-10-26 | Sarepta Therapeutics, Inc. | Antisense oligomers and methods of using the same for treating diseases associated with the acid alpha-glucosidase gene |
JP7422480B2 (ja) | 2016-05-04 | 2024-01-26 | アムジエン・インコーポレーテツド | 制御性t細胞の増殖のためのインターロイキン-2変異タンパク質 |
WO2018150345A1 (en) * | 2017-02-16 | 2018-08-23 | De Vita Bio Life Sciences | An expression vector |
AU2018292438A1 (en) | 2017-06-30 | 2019-12-12 | Zymeworks Bc Inc. | Stabilized chimeric fabs |
CN110343718A (zh) * | 2018-04-03 | 2019-10-18 | 新乡医学院 | 一种高效稳定的细胞表达载体、表达系统及其制备方法、应用 |
AU2020328038A1 (en) | 2019-08-13 | 2022-03-31 | Amgen Inc. | Interleukin-2 muteins for the expansion of T-regulatory cells |
KR20220114595A (ko) | 2019-12-17 | 2022-08-17 | 암젠 인크 | 치료에서의 사용을 위한 이중 인터류킨-2/tnf 수용체 효현제 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4956288A (en) * | 1988-04-22 | 1990-09-11 | Biogen, Inc. | Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA |
US5108901A (en) * | 1988-09-02 | 1992-04-28 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
CA2147006C (en) | 1992-10-05 | 2004-11-30 | William F. Thompson | Method for increasing expression and reducing expression variability of foreign genes in plant cells |
WO1994023041A2 (en) * | 1993-04-02 | 1994-10-13 | Ribogene, Inc. | Method for selective inactivation of viral replication |
US5773695A (en) | 1996-01-26 | 1998-06-30 | North Carolina State University | Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells |
IL127215A0 (en) | 1996-06-06 | 1999-09-22 | Novartis Ag | Vectors comprising sar elements |
NZ333323A (en) | 1996-06-11 | 2000-02-28 | Pioneer Hi Bred Int | A synthetic plant core promoter |
US6245974B1 (en) | 1997-08-06 | 2001-06-12 | North Carolina State University | Matrix attachment regions |
KR100313559B1 (ko) | 1998-07-22 | 2002-03-08 | 허영섭 | 수용성 TGFβ 수용체를 발현하는 재조합 세포주 및 전기세포주를 이용한 암치료 방법 |
EP1117815A1 (de) * | 1998-09-29 | 2001-07-25 | Pioneer Hi-Bred International Inc. | Mar/sar elemente, die ein durch rsyn7 reguliertes konstrukt flankieren |
SG141239A1 (en) * | 2001-01-26 | 2008-04-28 | Selexis Sa | Matrix attachment regions and methods for use thereof |
-
2000
- 2000-07-29 KR KR10-2000-0043996A patent/KR100408844B1/ko active IP Right Review Request
-
2001
- 2001-07-27 US US10/343,303 patent/US7422874B2/en not_active Expired - Lifetime
- 2001-07-27 EP EP01957013A patent/EP1392835B1/de not_active Expired - Lifetime
- 2001-07-27 WO PCT/KR2001/001285 patent/WO2002014525A2/en active Application Filing
- 2001-07-27 ES ES01957013T patent/ES2333774T3/es not_active Expired - Lifetime
- 2001-07-27 CN CNB018135579A patent/CN1262663C/zh not_active Expired - Lifetime
- 2001-07-27 JP JP2002519651A patent/JP4138479B2/ja not_active Expired - Lifetime
- 2001-07-27 AT AT01957013T patent/ATE445704T1/de not_active IP Right Cessation
- 2001-07-27 DE DE60140218T patent/DE60140218D1/de not_active Expired - Lifetime
- 2001-07-27 AU AU2001278797A patent/AU2001278797A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP4138479B2 (ja) | 2008-08-27 |
DE60140218D1 (de) | 2009-11-26 |
US20040038394A1 (en) | 2004-02-26 |
WO2002014525A2 (en) | 2002-02-21 |
ES2333774T3 (es) | 2010-03-01 |
KR20020010327A (ko) | 2002-02-04 |
EP1392835A2 (de) | 2004-03-03 |
JP2004506428A (ja) | 2004-03-04 |
US7422874B2 (en) | 2008-09-09 |
EP1392835A4 (de) | 2006-04-19 |
CN1444657A (zh) | 2003-09-24 |
AU2001278797A1 (en) | 2002-02-25 |
CN1262663C (zh) | 2006-07-05 |
EP1392835B1 (de) | 2009-10-14 |
KR100408844B1 (ko) | 2003-12-06 |
WO2002014525A3 (en) | 2003-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |