ATE437956T1 - Verfahren zur herstellung von cytidin 5'- diphosphatcholin - Google Patents

Verfahren zur herstellung von cytidin 5'- diphosphatcholin

Info

Publication number
ATE437956T1
ATE437956T1 AT03728046T AT03728046T ATE437956T1 AT E437956 T1 ATE437956 T1 AT E437956T1 AT 03728046 T AT03728046 T AT 03728046T AT 03728046 T AT03728046 T AT 03728046T AT E437956 T1 ATE437956 T1 AT E437956T1
Authority
AT
Austria
Prior art keywords
choline
cdp
diphosphatcholine
aqueous medium
producing
Prior art date
Application number
AT03728046T
Other languages
English (en)
Inventor
Shin-Ichi Hashimoto
Hideki Oda
Original Assignee
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Bio Co Ltd
Application granted granted Critical
Publication of ATE437956T1 publication Critical patent/ATE437956T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03728046T 2002-05-08 2003-05-08 Verfahren zur herstellung von cytidin 5'- diphosphatcholin ATE437956T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002132917 2002-05-08
PCT/JP2003/005764 WO2003095660A1 (en) 2002-05-08 2003-05-08 Process for producing cytidine 5’-diphocphate choline

Publications (1)

Publication Number Publication Date
ATE437956T1 true ATE437956T1 (de) 2009-08-15

Family

ID=29416654

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03728046T ATE437956T1 (de) 2002-05-08 2003-05-08 Verfahren zur herstellung von cytidin 5'- diphosphatcholin

Country Status (10)

Country Link
US (1) US20050164359A1 (de)
EP (1) EP1502956B1 (de)
JP (1) JPWO2003095660A1 (de)
CN (1) CN100513576C (de)
AT (1) ATE437956T1 (de)
AU (1) AU2003234789A1 (de)
DE (1) DE60328595D1 (de)
ES (1) ES2329566T3 (de)
PT (1) PT1502956E (de)
WO (1) WO2003095660A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4520219B2 (ja) * 2004-05-28 2010-08-04 協和発酵バイオ株式会社 5−アミノレブリン酸の製造法
TW200741005A (en) 2005-08-10 2007-11-01 Kyowa Hakko Kogyo Kk A purification method of cytidine diphosphate
JP5112869B2 (ja) * 2005-08-23 2013-01-09 協和発酵バイオ株式会社 シチジンジリン酸コリンの製造法
US8288437B2 (en) * 2008-07-24 2012-10-16 Valent Biosciences Corporation Salts, aqueous liquid compositions containing salts of abscisic acid analogs and methods of their preparation
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
WO2011140516A2 (en) 2010-05-07 2011-11-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
US8916358B2 (en) 2010-08-31 2014-12-23 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
US9469861B2 (en) 2011-09-09 2016-10-18 Greenlight Biosciences, Inc. Cell-free preparation of carbapenems
CA2919383A1 (en) 2013-08-05 2015-02-12 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
CN107614682B (zh) 2015-03-30 2021-11-09 绿光生物科技股份有限公司 核糖核酸的无细胞生成
EP4293104A3 (de) 2016-04-06 2024-04-24 Greenlight Biosciences, Inc. Zellfreie herstellung von ribonukleinsäure
CN109207415B (zh) * 2017-07-07 2022-09-16 苏州华赛生物工程技术有限公司 一种生产胞二磷胆碱的重组微生物及生产胞二磷胆碱的方法
JP2020536570A (ja) 2017-10-11 2020-12-17 グリーンライト バイオサイエンシーズ インコーポレーテッドGreenlight Biosciences,Inc. ヌクレオシド三リン酸およびリボ核酸の生成のための方法および組成物
CN107488603A (zh) * 2017-10-19 2017-12-19 南通秋之友生物科技有限公司 一种过表达磷酸胆碱胞苷转移酶酿酒酵母基因工程菌及构建方法和应用
CN108424859B (zh) * 2017-11-23 2021-09-10 华东理工大学 生产胞磷胆碱的基因工程菌的构建与应用
AU2022344719A1 (en) 2021-09-10 2024-03-28 Kyowa Hakko Bio Co., Ltd. Recombinant microorganism used for producing cdp-choline, and method for producing cdp-choline using said recombinant microorganism
CN116790466B (zh) * 2023-07-19 2023-11-03 山东理工大学 一种工程改造枯草芽孢杆菌发酵生产胞磷胆碱的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4840758B1 (de) 1969-03-24 1973-12-03
JPS58110600A (ja) 1981-12-25 1983-07-01 Kyowa Hakko Kogyo Co Ltd ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド
JPS60221091A (ja) 1983-12-21 1985-11-05 Kyowa Hakko Kogyo Co Ltd 新規プロモ−タ−
JP2564268B2 (ja) 1985-08-28 1996-12-18 協和醗酵工業株式会社 融合抗原ポリペプチド
JPH0710235B2 (ja) * 1987-10-19 1995-02-08 協和醗酵工業株式会社 発酵法によるオロット酸の製造法
JPH0322979A (ja) 1989-06-19 1991-01-31 Kyowa Hakko Kogyo Co Ltd 新規プラスミノーゲン活性化因子
JP3369236B2 (ja) 1992-01-30 2003-01-20 協和醗酵工業株式会社 シチジンジリン酸コリンの製造法
KR0177841B1 (ko) * 1992-01-30 1999-04-01 나까무라 간노스께 시티딘 디인산 콜린의 제조방법
WO1999049073A1 (fr) 1998-03-20 1999-09-30 Yamasa Corporation Procede de production de cytidine 5'-diphosphate choline
JP3822006B2 (ja) 1999-10-08 2006-09-13 ヤマサ醤油株式会社 シチジン5’−ジリン酸コリンの製造法
JP2001238691A (ja) * 2000-02-29 2001-09-04 Kyowa Hakko Kogyo Co Ltd ヌクレオシド5’−三リン酸の製造方法
JP2002045185A (ja) * 2000-08-02 2002-02-12 Kyowa Hakko Kogyo Co Ltd F0F1−ATPaseおよび該酵素をコードするDNA

Also Published As

Publication number Publication date
EP1502956A1 (de) 2005-02-02
US20050164359A1 (en) 2005-07-28
WO2003095660A1 (en) 2003-11-20
CN1653188A (zh) 2005-08-10
AU2003234789A1 (en) 2003-11-11
DE60328595D1 (de) 2009-09-10
PT1502956E (pt) 2009-08-31
EP1502956A4 (de) 2007-08-22
EP1502956B1 (de) 2009-07-29
ES2329566T3 (es) 2009-11-27
CN100513576C (zh) 2009-07-15
JPWO2003095660A1 (ja) 2005-09-15

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