ATE430165T1 - Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten - Google Patents

Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten

Info

Publication number
ATE430165T1
ATE430165T1 AT01965941T AT01965941T ATE430165T1 AT E430165 T1 ATE430165 T1 AT E430165T1 AT 01965941 T AT01965941 T AT 01965941T AT 01965941 T AT01965941 T AT 01965941T AT E430165 T1 ATE430165 T1 AT E430165T1
Authority
AT
Austria
Prior art keywords
peptides
integrin binding
treatment methods
binding motif
sequences
Prior art date
Application number
AT01965941T
Other languages
German (de)
English (en)
Inventor
Yoshinari Kumagai
Russell Blacher
Toshiyuki Yoneda
Original Assignee
Acologix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acologix Inc filed Critical Acologix Inc
Application granted granted Critical
Publication of ATE430165T1 publication Critical patent/ATE430165T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4728—Calcium binding proteins, e.g. calmodulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Cell Biology (AREA)
  • Birds (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
AT01965941T 2000-08-16 2001-08-14 Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten ATE430165T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64103400A 2000-08-16 2000-08-16
US09/812,485 US6911425B2 (en) 2000-08-16 2001-03-19 Integrin binding motif containing peptides and methods of treating skeletal diseases
PCT/US2001/025542 WO2002014360A1 (en) 2000-08-16 2001-08-14 Integrin binding motif containing peptides and methods of treating skeletal diseases

Publications (1)

Publication Number Publication Date
ATE430165T1 true ATE430165T1 (de) 2009-05-15

Family

ID=27093672

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01965941T ATE430165T1 (de) 2000-08-16 2001-08-14 Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten

Country Status (11)

Country Link
US (5) US6911425B2 (enExample)
EP (1) EP1309616B1 (enExample)
JP (3) JP4318246B2 (enExample)
CN (1) CN100488980C (enExample)
AT (1) ATE430165T1 (enExample)
AU (2) AU2001286491B2 (enExample)
CA (1) CA2418716A1 (enExample)
DE (1) DE60138552D1 (enExample)
ES (1) ES2324153T3 (enExample)
MX (1) MXPA03001394A (enExample)
WO (1) WO2002014360A1 (enExample)

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DE69935220T2 (de) * 1998-05-18 2007-11-15 University College London Von menschlichem tumor stammendes polypeptidhormon phosphatonin
DK1313440T3 (da) * 2000-08-16 2008-11-03 Acologix Inc Dentalprodukter indeholdende knoglevækstforögende peptider
US6911425B2 (en) 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases
CN1889922B (zh) * 2003-12-01 2010-11-24 阿尔拉食品公司 骨桥蛋白在牙用制剂中的用途
US20060193916A1 (en) * 2005-01-07 2006-08-31 Acologix, Inc. Formulations of peptides for periodontal and dental treatments
WO2007011610A2 (en) 2005-07-18 2007-01-25 Acologix, Inc. Protein formulation for promoting hard tissue formation
CN100366302C (zh) * 2006-09-14 2008-02-06 清华大学 一种用于骨修复的矿化多肽材料及其制备方法
AU2008209473B2 (en) * 2007-01-22 2012-10-25 Orthotrophix, Inc. A peptide composition and a method of promoting cartilage formation
JP5519121B2 (ja) * 2008-06-02 2014-06-11 学校法人東日本学園 新規ｒｇｄ含有ペプチドおよび象牙質再生剤、骨再生剤、歯周組織再生剤
JP2013528618A (ja) * 2010-06-01 2013-07-11 ベル−エアー フレグランシズ インコーポレーテッド 口臭制御方法及び製品
RU2503458C1 (ru) * 2012-08-27 2014-01-10 Сергей Васильевич Чуйкин Способ местного лечения и профилактики основных стоматологических заболеваний у детей с хронической почечной недостаточностью с применением жевательного фитосубстрата
JP6692676B2 (ja) * 2016-04-12 2020-05-13 学校法人東日本学園 ネフロネクチンを含むう蝕治療剤
CN106943311A (zh) * 2017-04-07 2017-07-14 缪来耿 一种用于预防和或治疗牙周炎的牙膏及其制备方法
HUE067390T2 (hu) 2017-06-14 2024-10-28 Orthotrophix Inc TPX-100 peptid a térdízületi fájdalom enyhítésére
US11963996B2 (en) 2018-10-24 2024-04-23 Orthotrophix, Inc. Method of treating knee pain
CN109762069B (zh) * 2018-11-05 2022-01-14 广州领晟医疗科技有限公司 一种融合蛋白、其药物组合物及用途
JP2022502356A (ja) 2018-12-04 2022-01-11 オルソトロフィックス インコーポレイテッド 変形性関節症の治療に使用するための製剤
CN111265652B (zh) * 2020-02-27 2023-06-27 广州领晟医疗科技有限公司 多肽在制备治疗缺血性脑血管疾病的药物中的应用
CN111358935B (zh) * 2020-02-27 2023-06-27 广州领晟医疗科技有限公司 多肽在制备抗肿瘤和/或抑制肿瘤转移药物中的用途及药物
CN111249446B (zh) * 2020-02-27 2023-06-27 广州领晟医疗科技有限公司 多肽及其盐的新用途
CN111569046B (zh) * 2020-04-14 2023-06-27 广州领晟医疗科技有限公司 多肽在制备治疗胰腺炎药物中的用途及含有其的药物
US11793857B2 (en) 2020-10-01 2023-10-24 Orthotrophix, Inc. Hard tissue therapeutics

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DK1313440T3 (da) * 2000-08-16 2008-11-03 Acologix Inc Dentalprodukter indeholdende knoglevækstforögende peptider
US6911425B2 (en) * 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases

Also Published As

Publication number Publication date
JP2011032286A (ja) 2011-02-17
AU2001286491B2 (en) 2006-04-27
CN100488980C (zh) 2009-05-20
US20020197267A1 (en) 2002-12-26
US20090042791A1 (en) 2009-02-12
DE60138552D1 (de) 2009-06-10
MXPA03001394A (es) 2004-12-13
CN1458935A (zh) 2003-11-26
CA2418716A1 (en) 2002-02-21
JP4318246B2 (ja) 2009-08-19
US20090062201A1 (en) 2009-03-05
JP2007302673A (ja) 2007-11-22
AU8649101A (en) 2002-02-25
US20050163728A1 (en) 2005-07-28
US20070014742A1 (en) 2007-01-18
US7160862B2 (en) 2007-01-09
EP1309616A1 (en) 2003-05-14
WO2002014360A1 (en) 2002-02-21
EP1309616B1 (en) 2009-04-29
US6911425B2 (en) 2005-06-28
JP2004506654A (ja) 2004-03-04
EP1309616A4 (en) 2004-12-08
ES2324153T3 (es) 2009-07-31

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