ATE421583T1 - Isolierung von nukleinsäuren - Google Patents
Isolierung von nukleinsäurenInfo
- Publication number
- ATE421583T1 ATE421583T1 AT00929666T AT00929666T ATE421583T1 AT E421583 T1 ATE421583 T1 AT E421583T1 AT 00929666 T AT00929666 T AT 00929666T AT 00929666 T AT00929666 T AT 00929666T AT E421583 T1 ATE421583 T1 AT E421583T1
- Authority
- AT
- Austria
- Prior art keywords
- substituent
- sample
- isolation
- nucleic acids
- rna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Turbine Rotor Nozzle Sealing (AREA)
- Window Of Vehicle (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9910154.5A GB9910154D0 (en) | 1999-04-30 | 1999-04-30 | Polynucleotides |
GBGB9910158.6A GB9910158D0 (en) | 1999-04-30 | 1999-04-30 | Isolation of nucleic acid |
GBGB9910157.8A GB9910157D0 (en) | 1999-04-30 | 1999-04-30 | Polynucleotides |
GBGB9910156.0A GB9910156D0 (en) | 1999-04-30 | 1999-04-30 | Polynucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE421583T1 true ATE421583T1 (de) | 2009-02-15 |
Family
ID=27451902
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00929665T ATE347616T1 (de) | 1999-04-30 | 2000-05-02 | Ribonukleinsäurederivate |
AT00929666T ATE421583T1 (de) | 1999-04-30 | 2000-05-02 | Isolierung von nukleinsäuren |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00929665T ATE347616T1 (de) | 1999-04-30 | 2000-05-02 | Ribonukleinsäurederivate |
Country Status (6)
Country | Link |
---|---|
US (4) | US6794140B1 (de) |
EP (2) | EP1177281B1 (de) |
AT (2) | ATE347616T1 (de) |
AU (4) | AU4767300A (de) |
DE (2) | DE60032235T2 (de) |
WO (4) | WO2000066605A2 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1177281B1 (de) | 1999-04-30 | 2009-01-21 | Cyclops Genome Sciences Limited | Isolierung von nukleinsäuren |
US6677120B2 (en) | 2001-03-30 | 2004-01-13 | Isis Pharmaceuticals, Inc. | Building blocks for the solution phase synthesis of oligonucleotides |
CA2474910A1 (en) | 2002-02-01 | 2003-08-07 | Sequitur, Inc. | Oligonucleotide compositions with enhanced efficiency |
US20060009409A1 (en) * | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
US20040072226A1 (en) * | 2002-07-03 | 2004-04-15 | Stojanovic Milan N. | Movement of multi-enzymatic nanoassemblies on recognition landscapes |
US20040005568A1 (en) * | 2002-07-03 | 2004-01-08 | Stojanovic Milan N. | Movement of multi-enzymatic nanoassemblies on recognition landscapes |
GB0217963D0 (en) | 2002-08-02 | 2002-09-11 | Cyclops Genome Sciences Ltd | Purification of nucleic acids |
DE10315581B4 (de) * | 2003-04-05 | 2007-06-28 | Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto | Verfahren zur Qualitätsbestimmung von RNA-Proben |
WO2005012522A1 (en) * | 2003-07-23 | 2005-02-10 | Cyclops Genome Sciences Limited | Clean-up beads |
GB0317199D0 (en) | 2003-07-23 | 2003-08-27 | Cyclops Genome Sciences Ltd | Clean-up beads |
DE10344819B4 (de) * | 2003-09-26 | 2017-06-29 | Sartorius Stedim Biotech Gmbh | Adsorptionsmembranen, Verfahren zur Herstellung derselben und Vorrichtungen, welche die Adsorptionsmembranen umfassen |
CA2586532C (en) | 2004-11-05 | 2014-03-25 | Qiagen North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
US20090075342A1 (en) * | 2005-04-26 | 2009-03-19 | Sharon Cload | Metabolic profile directed aptamer medicinal chemistry |
WO2006138145A1 (en) | 2005-06-14 | 2006-12-28 | Northwestern University | Nucleic acid functionalized nanoparticles for therapeutic applications |
US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
US8318424B2 (en) * | 2006-06-05 | 2012-11-27 | The University Of North Carolina At Chapel Hill | High-throughput RNA structure analysis |
US9506056B2 (en) * | 2006-06-08 | 2016-11-29 | Northwestern University | Nucleic acid functionalized nanoparticles for therapeutic applications |
JP5512285B2 (ja) * | 2007-02-09 | 2014-06-04 | ノースウェスタン ユニバーシティ | 細胞内標的を検出するための粒子 |
JP2010523078A (ja) * | 2007-03-30 | 2010-07-15 | キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | リボース環を含む修飾ポリヌクレオチド |
US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
CN102014919B (zh) | 2008-03-03 | 2015-02-25 | 托斯克公司 | 减少毒性的甲氨蝶呤佐剂及其使用方法 |
WO2009150156A1 (en) * | 2008-06-13 | 2009-12-17 | Riboxx Gmbh | Method for enzymatic synthesis of chemically modified rna |
AU2009316286B2 (en) | 2008-11-24 | 2016-05-26 | Northwestern University | Polyvalent RNA-nanoparticle compositions |
US20100233270A1 (en) * | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
SG2014011381A (en) | 2009-02-13 | 2014-06-27 | Chem Inc X | Methods of creating and screening dna-encoded libraries |
EP2272976A1 (de) * | 2009-07-06 | 2011-01-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur Differenzierung von Polynucleotid-Strängen |
EP2854056A3 (de) | 2009-09-30 | 2015-06-03 | Natera, Inc. | Verfahren zur nichtinvasiven pränatalen Ploidiezuordnung |
WO2011053940A2 (en) | 2009-10-30 | 2011-05-05 | Northwestern University | Templated nanoconjugates |
EP2333102A1 (de) * | 2009-12-14 | 2011-06-15 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur Identifizierung von RNA-Liganden |
US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
EP2572003A4 (de) | 2010-05-18 | 2016-01-13 | Natera Inc | Verfahren zur nichtinvasiven pränatalen ploidiezuordnung |
US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
EP2388324A1 (de) | 2010-05-20 | 2011-11-23 | Siemens Healthcare Diagnostics Inc. | Kontrollmaterial für Nukleinsäureteste |
FR2968302B1 (fr) | 2010-12-06 | 2012-11-30 | Biomerieux Sa | Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits |
JP6328934B2 (ja) | 2010-12-22 | 2018-05-23 | ナテラ, インコーポレイテッド | 非侵襲性出生前親子鑑定法 |
BR112013020220B1 (pt) | 2011-02-09 | 2020-03-17 | Natera, Inc. | Método para determinar o estado de ploidia de um cromossomo em um feto em gestação |
EP3351631B1 (de) * | 2011-09-07 | 2020-11-04 | X-Chem, Inc. | Verfahren zur markierung dna-codierter bibliotheken |
CN104023749B (zh) | 2011-09-14 | 2019-12-17 | 西北大学 | 能穿过血脑屏障的纳米缀合物 |
US9480966B2 (en) | 2012-04-30 | 2016-11-01 | General Electric Company | Substrates and methods for collection, stabilization and elution of biomolecules |
US9040675B2 (en) | 2012-04-30 | 2015-05-26 | General Electric Company | Formulations for nucleic acid stabilization on solid substrates |
US9044738B2 (en) | 2012-04-30 | 2015-06-02 | General Electric Company | Methods and compositions for extraction and storage of nucleic acids |
US9040679B2 (en) | 2012-04-30 | 2015-05-26 | General Electric Company | Methods and compositions for extraction and storage of nucleic acids |
ES2855137T3 (es) | 2012-07-13 | 2021-09-23 | X Chem Inc | Bibliotecas codificadas por ADN que tienen vínculos de oligonucleótidos codificadores que no se pueden leer por polimerasas |
FR2994184B1 (fr) | 2012-08-02 | 2017-12-08 | Biomerieux Sa | Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits |
WO2014093688A1 (en) * | 2012-12-12 | 2014-06-19 | 1Massachusetts Institute Of Technology | Compositions and methods for functional nucleic acid delivery |
US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
US10240188B2 (en) | 2013-10-07 | 2019-03-26 | The University Of North Carolina At Chapel Hill | Detection of chemical modifications in nucleic acids |
EP3134541B1 (de) | 2014-04-21 | 2020-08-19 | Natera, Inc. | Nachweis von ploidien in chromosomalen segmenten in krebs |
WO2015164773A1 (en) | 2014-04-25 | 2015-10-29 | Shire Human Genetic Therapies, Inc. | Methods for purification of messenger rna |
CN107405540A (zh) * | 2014-10-24 | 2017-11-28 | 雅培分子公司 | 小核酸的富集 |
CN107106493A (zh) | 2014-11-21 | 2017-08-29 | 西北大学 | 球形核酸纳米颗粒缀合物的序列特异性细胞摄取 |
DK3294885T3 (da) | 2015-05-08 | 2020-08-10 | Curevac Real Estate Gmbh | Fremgangsmåde til at fremstille rna |
WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
WO2016193206A1 (en) | 2015-05-29 | 2016-12-08 | Curevac Ag | A method for producing and purifying rna, comprising at least one step of tangential flow filtration |
BR112017026193B1 (pt) | 2015-06-05 | 2021-09-14 | W.R. Grace & Co-Conn | Adsorventes, método de produção dos adsorventes e uso dos adsorventes |
EP4035762B1 (de) | 2015-09-09 | 2023-11-01 | Drawbridge Health, Inc. | Vorrichtungen zur probeentnahme, stabilisierung und konservierung |
US10214739B2 (en) * | 2015-10-30 | 2019-02-26 | Axagarius Gmbh & Co. Kg | RNA binding solution |
WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
JP7094949B2 (ja) | 2016-11-07 | 2022-07-04 | ナノスール エルエルシー | 転写後化学修飾二重鎖rna |
US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
CN110234277B (zh) | 2017-01-10 | 2022-07-05 | 集联健康有限公司 | 用于样品收集的装置、系统和方法 |
US10894976B2 (en) * | 2017-02-21 | 2021-01-19 | Natera, Inc. | Compositions, methods, and kits for isolating nucleic acids |
US11053608B2 (en) * | 2017-06-16 | 2021-07-06 | Boris Farber | Combinatorial derivatives of RNA oligonucleotides |
IL297543A (en) | 2017-11-30 | 2022-12-01 | Arrakis Therapeutics Inc | Nucleic acid-binding photoprobes and their uses |
WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
FR3078977B1 (fr) * | 2018-03-16 | 2023-03-17 | Biomerieux Sa | Procede d'extraction d'acides nucleiques |
WO2019200228A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
US11525159B2 (en) | 2018-07-03 | 2022-12-13 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
CA3228823A1 (en) * | 2021-08-31 | 2023-03-09 | Darren H. Wakefield | High molecular weight modified dsrna compositions |
WO2023101963A2 (en) * | 2021-11-30 | 2023-06-08 | Northwestern University | Compositions for inhibiting dipeptide repeat protein-ribosomal rna interaction and uses thereof |
WO2024167836A1 (en) * | 2023-02-06 | 2024-08-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and modifications for reducing innate immune responses to rna |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4588718A (en) * | 1984-03-28 | 1986-05-13 | The Upjohn Company | Carboxy containing ester prodrugs of corticosteroids |
US5681726A (en) * | 1988-09-19 | 1997-10-28 | Stratagene | Method of double stranded DNA synthesis |
US5859221A (en) * | 1990-01-11 | 1999-01-12 | Isis Pharmaceuticals, Inc. | 2'-modified oligonucleotides |
US5872232A (en) * | 1990-01-11 | 1999-02-16 | Isis Pharmaceuticals Inc. | 2'-O-modified oligonucleotides |
US5660985A (en) * | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
US5707796A (en) | 1990-06-11 | 1998-01-13 | Nexstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
DE69133511T2 (de) * | 1990-08-13 | 2006-09-28 | Isis Pharmaceuticals, Inc., Carlsbad | Zuckermodifizierte oligonukleotide zum erkennen und steuern der genexpression |
US5426180A (en) * | 1991-03-27 | 1995-06-20 | Research Corporation Technologies, Inc. | Methods of making single-stranded circular oligonucleotides |
US6235887B1 (en) * | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
CA2156394A1 (en) | 1993-02-24 | 1994-09-01 | Jui H. Wang | Compositions and methods of application of reactive antiviral polymers |
CA2174339A1 (en) * | 1993-10-27 | 1995-05-04 | Lech W. Dudycz | 2'-amido and 2'-peptido modified oligonucleotides |
US5700642A (en) * | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
CA2261892A1 (en) * | 1996-07-24 | 1998-01-29 | Michelle M. Hanna | Base-protected nucleotide analogs with protected thiol groups |
US5849902A (en) * | 1996-09-26 | 1998-12-15 | Oligos Etc. Inc. | Three component chimeric antisense oligonucleotides |
EP2292771A3 (de) * | 1997-09-19 | 2011-07-27 | Life Technologies Corporation | Sense mRNA Therapie |
DE19801153A1 (de) * | 1998-01-14 | 1999-07-15 | Jenne Andreas | Verfahren zur Selektion von Ribozymen, die Ribonucleinsäuren in trans an 2'-OH-Gruppen kovalent modifizieren können und durch dieses Verfahren erhältliche Ribozyme |
AU751480B2 (en) * | 1998-04-29 | 2002-08-15 | Ribozyme Pharmaceuticals, Inc. | Nucleoside triphosphates and their incorporation into ribozymes |
ATE251181T1 (de) | 1998-07-28 | 2003-10-15 | Micromet Ag | Heterominikörper |
EP1177281B1 (de) * | 1999-04-30 | 2009-01-21 | Cyclops Genome Sciences Limited | Isolierung von nukleinsäuren |
US6720144B1 (en) * | 2001-06-21 | 2004-04-13 | Quest Diagnostics | Detection of clonal T-cell receptor-γ gene rearrangement by PCR/temporal temperature gradient gel electrophoresis (TTGE) |
GB0217963D0 (en) | 2002-08-02 | 2002-09-11 | Cyclops Genome Sciences Ltd | Purification of nucleic acids |
WO2005012522A1 (en) | 2003-07-23 | 2005-02-10 | Cyclops Genome Sciences Limited | Clean-up beads |
-
2000
- 2000-05-02 EP EP00929666A patent/EP1177281B1/de not_active Expired - Lifetime
- 2000-05-02 AT AT00929665T patent/ATE347616T1/de not_active IP Right Cessation
- 2000-05-02 AU AU47673/00A patent/AU4767300A/en not_active Abandoned
- 2000-05-02 AT AT00929666T patent/ATE421583T1/de not_active IP Right Cessation
- 2000-05-02 US US10/031,636 patent/US6794140B1/en not_active Expired - Fee Related
- 2000-05-02 AU AU45880/00A patent/AU4588000A/en not_active Abandoned
- 2000-05-02 WO PCT/GB2000/001687 patent/WO2000066605A2/en active Application Filing
- 2000-05-02 EP EP00929665A patent/EP1196631B1/de not_active Expired - Lifetime
- 2000-05-02 WO PCT/GB2000/001683 patent/WO2001094626A1/en active IP Right Grant
- 2000-05-02 DE DE60032235T patent/DE60032235T2/de not_active Expired - Lifetime
- 2000-05-02 WO PCT/GB2000/001684 patent/WO2000075302A2/en active Application Filing
- 2000-05-02 AU AU47674/00A patent/AU4767400A/en not_active Abandoned
- 2000-05-02 WO PCT/GB2000/001670 patent/WO2000075306A2/en active Application Filing
- 2000-05-02 DE DE60041442T patent/DE60041442D1/de not_active Expired - Fee Related
- 2000-05-02 AU AU45890/00A patent/AU4589000A/en not_active Abandoned
-
2001
- 2001-10-26 US US10/011,495 patent/US6867290B2/en not_active Expired - Fee Related
-
2004
- 2004-04-08 US US10/820,423 patent/US7244568B2/en not_active Expired - Fee Related
-
2005
- 2005-02-14 US US11/057,808 patent/US20050272679A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1177281A2 (de) | 2002-02-06 |
US7244568B2 (en) | 2007-07-17 |
EP1196631B1 (de) | 2006-12-06 |
AU4767300A (en) | 2001-12-17 |
AU4589000A (en) | 2000-11-17 |
ATE347616T1 (de) | 2006-12-15 |
WO2001094626A1 (en) | 2001-12-13 |
AU4767400A (en) | 2000-12-28 |
WO2000075302A2 (en) | 2000-12-14 |
EP1196631A1 (de) | 2002-04-17 |
US20050074753A1 (en) | 2005-04-07 |
EP1177281B1 (de) | 2009-01-21 |
AU4588000A (en) | 2000-12-28 |
DE60032235D1 (de) | 2007-01-18 |
WO2000066605A2 (en) | 2000-11-09 |
US20030039985A1 (en) | 2003-02-27 |
WO2000075306A2 (en) | 2000-12-14 |
US6867290B2 (en) | 2005-03-15 |
US6794140B1 (en) | 2004-09-21 |
US20050272679A1 (en) | 2005-12-08 |
WO2000075302A3 (en) | 2001-04-26 |
WO2000066605A3 (en) | 2001-04-26 |
DE60041442D1 (de) | 2009-03-12 |
DE60032235T2 (de) | 2007-11-15 |
WO2000075306A3 (en) | 2001-05-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE421583T1 (de) | Isolierung von nukleinsäuren | |
KR920701478A (ko) | 핵산서열의 증폭방법 | |
EP1068356B8 (de) | Adressierbare protein arrays | |
ES2195171T3 (es) | Sistema de transposicion in vitro usando transposasa tn5 modificada. | |
KR100204360B1 (en) | A method for identifying a polynucleotide molecule having a selected nucleic acid sequence from a library of random or semi-random polynucleotide molecules | |
ATE426045T1 (de) | Prozess zur synthetisierung von nukleinsaure | |
SE8800864D0 (sv) | Method of assaying of nucleic acids, a reagent combination and kit therefore | |
ATE144290T1 (de) | Amplifikationsverfahren | |
DK0923598T3 (da) | Fremstilling og anvendelse af normaliserede DNA-biblioteker | |
CA2230967A1 (en) | Improved nucleic acid assays | |
DE69731939D1 (de) | Isolierung von einzelsträngigen nukleinsäuren | |
FI883722A0 (fi) | Alfa-amiderande enzymkompositioner och foerfaranden foer deras framstaellning och anvaendning. | |
WO2000053804A3 (en) | Genetic screening | |
DE50213370D1 (de) | Mikrofluidisches extraktionsverfahren | |
EP0293079A3 (de) | Chlamydia-Vakzin | |
SE8602416D0 (sv) | Gen for ligninnedbrytning och anvendning derav | |
ATE366302T1 (de) | Ein polynucleotidmotor, ein motorsystem, seine herstellung und verwendungen | |
PL146824B1 (en) | Method of obtaining 4-sulfanilamido-2,6-dimetoxypyrimidine | |
WO1997037040A3 (en) | Isolation and/or amplification of hepatitis c virus (hcv) nucleic acids from samples suspected to contain hcv | |
ES2090312T3 (es) | Segmentos de adn y microorganismos transformados que comprenden el gen de la delta-1-deshidrogenasa, y sus aplicaciones. | |
JPS5589274A (en) | Coriloxin and its preparation | |
MX9708943A (es) | Genes de polifenol oxidasa de la lengua y platano. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |