ATE407121T1 - Gegen säurebeständige bakterien wirksame antibakterielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten - Google Patents
Gegen säurebeständige bakterien wirksame antibakterielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthaltenInfo
- Publication number
- ATE407121T1 ATE407121T1 AT01904335T AT01904335T ATE407121T1 AT E407121 T1 ATE407121 T1 AT E407121T1 AT 01904335 T AT01904335 T AT 01904335T AT 01904335 T AT01904335 T AT 01904335T AT E407121 T1 ATE407121 T1 AT E407121T1
- Authority
- AT
- Austria
- Prior art keywords
- active ingredient
- carboxylic acids
- antibacterial agents
- effective against
- resistant bacteria
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000038099 | 2000-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE407121T1 true ATE407121T1 (de) | 2008-09-15 |
Family
ID=18561886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01904335T ATE407121T1 (de) | 2000-02-09 | 2001-02-07 | Gegen säurebeständige bakterien wirksame antibakterielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7176313B2 (de) |
| EP (1) | EP1262477B1 (de) |
| KR (1) | KR100817425B1 (de) |
| CN (1) | CN1312131C (de) |
| AT (1) | ATE407121T1 (de) |
| AU (2) | AU2001232238B2 (de) |
| CA (1) | CA2398988C (de) |
| DE (1) | DE60135640D1 (de) |
| DK (1) | DK1262477T3 (de) |
| ES (1) | ES2312411T3 (de) |
| HK (1) | HK1048118B (de) |
| IL (2) | IL151035A0 (de) |
| MX (1) | MXPA02007667A (de) |
| NO (1) | NO325656B1 (de) |
| PT (1) | PT1262477E (de) |
| RU (2) | RU2297420C2 (de) |
| TW (1) | TWI283668B (de) |
| WO (1) | WO2001058876A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002236267A1 (en) * | 2002-03-08 | 2003-09-22 | Daiichi Pharmaceutical Co., Ltd. | Quinolonecarboxylic acid derivative |
| US7459005B2 (en) | 2002-11-22 | 2008-12-02 | Akzo Nobel N.V. | Chemical composition and method |
| DE10314634A1 (de) * | 2003-04-01 | 2004-10-14 | Khs Maschinen- Und Anlagenbau Ag, Patentabteilung | Spülbares Huborgan |
| PT1666477E (pt) | 2003-09-10 | 2013-08-28 | Kyorin Seiyaku Kk | Derivado de 7-(4-substituído-3-ciclopropilaminometil-1- pirrolidinil) quinolonecarboxílico |
| ES2402420T3 (es) * | 2003-09-29 | 2013-05-03 | Daiichi Sankyo Company, Limited | Derivado del ácido 8-cianoquinolonacarboxílico |
| ITMI20032259A1 (it) * | 2003-11-20 | 2005-05-21 | Chemi Spa | Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione |
| TW200640899A (en) * | 2005-01-21 | 2006-12-01 | Daiichi Seiyaku Co | Fluoroalkylpyrrolidine derivative |
| EP1930006A4 (de) * | 2005-09-28 | 2010-10-13 | Daiichi Sankyo Co Ltd | Verfahren zur herstellung einer chinolon-haltigen lyophilisierten zubereitung |
| JP5174365B2 (ja) * | 2007-03-23 | 2013-04-03 | 第一三共株式会社 | キノロン含有凍結乾燥製剤の製造方法 |
| EP2149571A4 (de) * | 2007-05-24 | 2010-09-01 | Kyorin Seiyaku Kk | Mutilin-derivat mit einer ringförmigen, heterozyklischen und aromatischen carboxylsäurestruktur in einem substituenten an position 14 |
| BRPI0914254A2 (pt) | 2008-06-17 | 2015-11-03 | Inst Nat Sante Rech Med | compostos anti-infectivos |
| WO2010131054A1 (en) | 2009-05-15 | 2010-11-18 | Bradford Pharma Limited | Redox drug derivatives |
| KR20130088002A (ko) * | 2010-01-13 | 2013-08-07 | 재단법인 한국파스퇴르연구소 | 항-감염성 피리도(1,2-ａ)피리미딘 |
| CN103381169A (zh) * | 2013-07-04 | 2013-11-06 | 丁圣雨 | Chukrasone A在抗结核菌药物中的应用 |
| KR20230085439A (ko) | 2021-12-07 | 2023-06-14 | 대한민국(국립마산병원장) | 비결핵 항산균 감염 질환의 예방 또는 치료용 조성물 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5872589A (ja) * | 1981-10-28 | 1983-04-30 | Dai Ichi Seiyaku Co Ltd | ピリド〔１，２，３−ｄｅ〕〔１，４〕ベンゾオキサジン誘導体 |
| DE3576335D1 (de) * | 1984-12-14 | 1990-04-12 | Daiichi Seiyaku Co | Chinolincarbonsaeure-derivate. |
| JPS61205258A (ja) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceut Co Ltd | キノロンカルボン酸誘導体及びその製造方法 |
| US4977154A (en) * | 1985-12-12 | 1990-12-11 | Warner-Lambert Company | 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents |
| JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| US4777253A (en) * | 1986-04-25 | 1988-10-11 | Abbott Laboratories | Process for preparation of racemate and optically active ofloxacin and related derivatives |
| EP0319906A3 (de) * | 1987-12-11 | 1990-05-02 | Dainippon Pharmaceutical Co., Ltd. | Chinolinderivate, Verfahren zu ihrer Herstellung und sie enthaltendes antibakterielles Mittel |
| MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
| ATE92633T1 (de) | 1988-05-11 | 1993-08-15 | Abbott Lab | Verfahren zur erhoehung der spezifizitaet in kompetitiven immuntests. |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| AU618823B2 (en) * | 1988-07-20 | 1992-01-09 | Sankyo Company Limited | 4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use |
| JP3026162B2 (ja) * | 1988-08-31 | 2000-03-27 | 第一製薬株式会社 | スピロ化合物 |
| CA1336090C (en) | 1988-08-31 | 1995-06-27 | Isao Hayakawa | Spiro-substituted cyclic amines of quinolone derivatives |
| JPH0324013A (ja) * | 1989-06-21 | 1991-02-01 | Kyowa Hakko Kogyo Co Ltd | 抗腫瘍剤 |
| JPH0381224A (ja) * | 1989-08-22 | 1991-04-05 | Otsuka Pharmaceut Co Ltd | ライ病治療剤 |
| US6075024A (en) * | 1991-11-27 | 2000-06-13 | Sepracor Inc. | Methods for treating infection using optically pure (S)-lomefloxacin |
| NO304832B1 (no) * | 1992-05-27 | 1999-02-22 | Ube Industries | Aminokinolonderivater samt middel mot HIV |
| JPH0649059A (ja) * | 1992-07-23 | 1994-02-22 | Hokuriku Seiyaku Co Ltd | ７−（５−アザスピロ〔２，４〕ヘプタン−５−イル）−８−アルコキシキノリン−３−カルボン酸誘導体 |
| JP3268098B2 (ja) * | 1992-12-25 | 2002-03-25 | 第一製薬株式会社 | 二環性環状アミン誘導体 |
| JPH06271568A (ja) * | 1993-03-22 | 1994-09-27 | Hokuriku Seiyaku Co Ltd | ７−フェニルピペラジニルキノリン−３−カルボン酸誘導体 |
| TW252107B (de) | 1993-08-27 | 1995-07-21 | Hokuriku Pharmacetical Co Ltd | |
| IL151451A0 (en) * | 2000-02-25 | 2003-04-10 | Daiichi Seiyaku Co | Process for producing quinolonecarboxylic acids and intermediates thereof |
| AU2001244671B2 (en) * | 2000-03-31 | 2005-01-27 | Daiichi Pharmaceutical Co., Ltd. | Quinolonecarboxylic acid derivative |
-
2001
- 2001-02-07 EP EP01904335A patent/EP1262477B1/de not_active Expired - Lifetime
- 2001-02-07 PT PT01904335T patent/PT1262477E/pt unknown
- 2001-02-07 MX MXPA02007667A patent/MXPA02007667A/es active IP Right Grant
- 2001-02-07 ES ES01904335T patent/ES2312411T3/es not_active Expired - Lifetime
- 2001-02-07 AU AU2001232238A patent/AU2001232238B2/en not_active Ceased
- 2001-02-07 RU RU2004137055/04A patent/RU2297420C2/ru not_active IP Right Cessation
- 2001-02-07 CN CNB018077331A patent/CN1312131C/zh not_active Expired - Fee Related
- 2001-02-07 US US10/203,199 patent/US7176313B2/en not_active Expired - Fee Related
- 2001-02-07 RU RU2002121245/04A patent/RU2299205C2/ru not_active IP Right Cessation
- 2001-02-07 WO PCT/JP2001/000861 patent/WO2001058876A1/ja active IP Right Grant
- 2001-02-07 DK DK01904335T patent/DK1262477T3/da active
- 2001-02-07 IL IL15103501A patent/IL151035A0/xx unknown
- 2001-02-07 CA CA2398988A patent/CA2398988C/en not_active Expired - Fee Related
- 2001-02-07 AT AT01904335T patent/ATE407121T1/de active
- 2001-02-07 DE DE60135640T patent/DE60135640D1/de not_active Expired - Lifetime
- 2001-02-07 KR KR1020027010292A patent/KR100817425B1/ko not_active IP Right Cessation
- 2001-02-07 AU AU3223801A patent/AU3223801A/xx active Pending
- 2001-02-09 TW TW090102897A patent/TWI283668B/zh not_active IP Right Cessation
-
2002
- 2002-08-01 IL IL151035A patent/IL151035A/en not_active IP Right Cessation
- 2002-08-08 NO NO20023764A patent/NO325656B1/no not_active IP Right Cessation
-
2003
- 2003-01-13 HK HK03100293.1A patent/HK1048118B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TWI283668B (en) | 2007-07-11 |
| CN1422256A (zh) | 2003-06-04 |
| KR20020074517A (ko) | 2002-09-30 |
| US7176313B2 (en) | 2007-02-13 |
| EP1262477A1 (de) | 2002-12-04 |
| US20030119848A1 (en) | 2003-06-26 |
| HK1048118A1 (en) | 2003-03-21 |
| WO2001058876A1 (fr) | 2001-08-16 |
| EP1262477A4 (de) | 2003-07-02 |
| MXPA02007667A (es) | 2003-04-14 |
| EP1262477B1 (de) | 2008-09-03 |
| NO20023764L (no) | 2002-10-09 |
| PT1262477E (pt) | 2008-11-14 |
| RU2002121245A (ru) | 2004-04-10 |
| RU2299205C2 (ru) | 2007-05-20 |
| ES2312411T3 (es) | 2009-03-01 |
| AU2001232238B2 (en) | 2005-03-24 |
| NO325656B1 (no) | 2008-06-30 |
| DK1262477T3 (da) | 2008-12-01 |
| HK1048118B (zh) | 2009-01-09 |
| IL151035A0 (en) | 2003-04-10 |
| KR100817425B1 (ko) | 2008-03-27 |
| AU3223801A (en) | 2001-08-20 |
| IL151035A (en) | 2008-12-29 |
| DE60135640D1 (de) | 2008-10-16 |
| CN1312131C (zh) | 2007-04-25 |
| CA2398988A1 (en) | 2001-08-16 |
| NO20023764D0 (no) | 2002-08-08 |
| RU2297420C2 (ru) | 2007-04-20 |
| CA2398988C (en) | 2010-06-22 |
| RU2004137055A (ru) | 2006-05-27 |
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