ATE381561T1 - Verfahren zur herstellung von chiralen propionsäurederivaten - Google Patents

Verfahren zur herstellung von chiralen propionsäurederivaten

Info

Publication number
ATE381561T1
ATE381561T1 AT04765444T AT04765444T ATE381561T1 AT E381561 T1 ATE381561 T1 AT E381561T1 AT 04765444 T AT04765444 T AT 04765444T AT 04765444 T AT04765444 T AT 04765444T AT E381561 T1 ATE381561 T1 AT E381561T1
Authority
AT
Austria
Prior art keywords
sup
propionic acid
acid derivatives
formula
producing chiral
Prior art date
Application number
AT04765444T
Other languages
English (en)
Inventor
Kurt Puentener
Michelangelo Scalone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE381561T1 publication Critical patent/ATE381561T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
AT04765444T 2003-09-29 2004-09-21 Verfahren zur herstellung von chiralen propionsäurederivaten ATE381561T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03021700 2003-09-29

Publications (1)

Publication Number Publication Date
ATE381561T1 true ATE381561T1 (de) 2008-01-15

Family

ID=34354426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04765444T ATE381561T1 (de) 2003-09-29 2004-09-21 Verfahren zur herstellung von chiralen propionsäurederivaten

Country Status (14)

Country Link
US (2) US7262303B2 (de)
EP (1) EP1670792B1 (de)
JP (2) JP4627299B2 (de)
KR (1) KR100854886B1 (de)
CN (1) CN1860115B (de)
AT (1) ATE381561T1 (de)
CA (1) CA2539176C (de)
DE (1) DE602004010830T2 (de)
DK (1) DK1670792T3 (de)
ES (1) ES2297463T3 (de)
IL (1) IL174360A (de)
MX (1) MXPA06003365A (de)
TW (1) TWI333491B (de)
WO (1) WO2005030764A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7262303B2 (en) * 2003-09-29 2007-08-28 Hoffman-La Roche Inc. Process for the production of chiral propionic acid derivatives
CA2648246C (en) * 2006-04-03 2014-02-18 F. Hoffmann-La Roche Ag Process for preparation of enantiomerically enriched cyclic .beta.-aryl or heteroaryl carboxylic acids
EP2093084B1 (de) * 2008-02-23 2011-06-22 GM Global Technology Operations, Inc. Kondensatablaufrohr für Heizungs-, Lüftungs- und/oder Klimaanlage und Verfahren für die Montage eines Kondensatablaufrohrs
JP2012512221A (ja) * 2008-12-16 2012-05-31 エフ.ホフマン−ラ ロシュ アーゲー ピロリジン−3−カルボン酸の製造方法
AU2010206249B2 (en) * 2009-01-23 2015-07-09 F. Hoffmann-La Roche Ag Pharmaceutical composition comprising aleglitazar
US8450496B2 (en) 2009-03-24 2013-05-28 Hoffman-La Roche Inc. Process for the preparation of propionic acid derivatives
SG182259A1 (en) 2009-12-07 2012-08-30 Hoffmann La Roche Process for the preparation of propionic acid derivatives
WO2013181384A1 (en) 2012-05-31 2013-12-05 Ratiopharm Gmbh Solid state forms of aleglitazar sodium
WO2014016369A1 (en) 2012-07-27 2014-01-30 Ratiopharm Gmbh Pharmaceutical formulation comprising aleglitazar and complexing agent
EP2895469B1 (de) * 2012-09-12 2017-10-18 F. Hoffmann-La Roche AG Feste formen von (s)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzo[b]thiophen-7-yl}-propionic sauer und salze davon
AU2022327461A1 (en) * 2021-08-13 2024-02-01 Alebund Pharmaceuticals (Hong Kong) Limited Deuterated compounds
CN114669333B (zh) * 2022-04-25 2023-06-23 中山大学 一种催化α-季碳醛脱羰氢化的催化剂体系和催化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570764B1 (de) * 1992-05-18 2001-07-18 F.Hoffmann-La Roche & Co. Aktiengesellschaft Asymmetrische Hydrierung
US6222039B1 (en) * 1998-07-13 2001-04-24 Hoffman-La Roche Inc. Process for the preparation of chiral lactones
PL351987A1 (en) * 1999-04-28 2003-07-14 Reddys Lab Ltd Dr Substitution bicyclic-heterocyclic compounds, method of obtaining thereof, and use of such compounds to control adiposis and to reduce the level of cholesterol
EP1392295B1 (de) * 2001-05-15 2006-05-31 F. Hoffmann-La Roche AG Carbonsäure-substituierte oxazol-derivate zur verwendung als ppar-alpha und -gamma aktivatoren zur behandlung von diabetes
TWI343915B (en) * 2002-10-07 2011-06-21 Hoffmann La Roche Chirale ppar agonists
US7262303B2 (en) * 2003-09-29 2007-08-28 Hoffman-La Roche Inc. Process for the production of chiral propionic acid derivatives

Also Published As

Publication number Publication date
CA2539176C (en) 2010-01-05
EP1670792B1 (de) 2007-12-19
JP4627299B2 (ja) 2011-02-09
TW200524919A (en) 2005-08-01
ES2297463T3 (es) 2008-05-01
US7262303B2 (en) 2007-08-28
CN1860115B (zh) 2011-09-07
IL174360A0 (en) 2006-08-01
US20070249842A1 (en) 2007-10-25
JP2007506800A (ja) 2007-03-22
US20050070714A1 (en) 2005-03-31
KR100854886B1 (ko) 2008-08-28
CA2539176A1 (en) 2005-04-07
WO2005030764A1 (en) 2005-04-07
JP5279789B2 (ja) 2013-09-04
CN1860115A (zh) 2006-11-08
EP1670792A1 (de) 2006-06-21
DE602004010830T2 (de) 2008-12-24
KR20060056405A (ko) 2006-05-24
MXPA06003365A (es) 2006-06-08
JP2011037886A (ja) 2011-02-24
DE602004010830D1 (de) 2008-01-31
DK1670792T3 (da) 2008-04-21
IL174360A (en) 2011-10-31
TWI333491B (en) 2010-11-21
US7365207B2 (en) 2008-04-29

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